UAB-HudsonAlpha Genomic Medicine Training Program

UAB-HudsonAlpha 基因组医学培训计划

• 批准号: 10403651
• 负责人: Gregory Stefan Barsh
• 金额: $ 31.68万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-06-01 至 2026-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10403651
• 关键词: Genomic medicine; Training Programs

Project Summary The UAB-HudsonAlpha Genomic Medicine Training Program was established four years ago to train leaders in the integration of genetics and genomics into medical practice. We have recruited fellows with an MD, PhD, or PharmD degree who participate in customized educational training and pursue mentored research at UAB or HudsonAlpha. The educational plan is based on a set of competencies that equip the trainee with the knowledge and skill set to be an independent genomic medicine researcher. Each trainee also completes a genomic medicine practicum that provides exposure to clinics and clinical laboratories, an educational outreach project, an opportunity to explore entrepreneurship career opportunities, and training in the responsible conduct of research and rigor and reproducibility in research. The trainees carry out mentored research under the auspices of one of 60 program faculty, as part of an individualized development plan. Conferences at UAB and HudsonAlpha include research seminars, genome sequencing case review conferences, a molecular tumor board, and a monthly genomic medicine meeting, which provide a foundation and common platform for all trainees. All trainees attend the annual NHGRI training conference and present either posters or platform presentations and present their work at a Work in Progress seminar at UAB. Trainee progress is monitored in biannual written reports and meetings with each trainee and mentor together with the program co-directors. Several innovations have been instituted since the inception of the program four years ago. These include the monthly genomic medicine conference and the entrepreneurship practicum; the latter leverages the strong relationship of HudsonAlpha with biotechnology companies hosted on the HudsonAlpha campus. In order to increase our ability to recruit MDs, we have forged relationships with the UAB Department of Surgery and Department of Medicine, both of which have programs that enable residents to pursue two or more years of research during the course of their training. We have also added an introductory lecture series on the basics of genomic medicine to ensure that all trainees are equipped with basic skills in genomic medicine, including, for example, data management and sharing. The required education in Rigor and Reproducibility in Research is also a new addition. We have strengthened our outreach efforts to enhance the recruitment of minorities to the program. This includes leveraging relationships we have forged with Historically Black Colleges and Universities in Alabama through our R25 DAP program “Summer Undergraduate Experience in Genomic Medicine (SURE-GM)” and with the Muscogee (Creek) Nation. Finally, we have adapted a program evaluation approach initially developed for SURE-GM to provide formal evaluation of our T32 Genomic Medicine Training Program.

项目摘要 UAB-HudsonAlpha基因组医学培训计划于四年前建立，旨在培训 将遗传学和基因组学整合到医疗实践中的领导者。我们已经招募了一些研究员 参加定制教育培训并接受指导的医学博士、博士或药学博士学位 在UAB或HudsonAlpha进行研究。教育计划基于一系列能力，这些能力为 具备成为独立基因组医学研究人员的知识和技能的受训人员。每位实习生 还完成了一项基因医学实践，提供了接触诊所和临床实验室的机会， 一个教育推广项目，一个探索创业职业机会的机会，以及 负责任地进行研究以及研究的严密性和重复性方面的培训。实习生 在60名项目教员的主持下进行指导研究，作为个性化项目的一部分 发展规划。UAB和HudsonAlpha的会议包括研究研讨会、基因组 测序案例审查会议，分子肿瘤委员会，和每月基因组药物 会议，为所有学员提供了一个基础和共同的平台。所有受训人员都参加年度 NHGRI培训会议并发布海报或平台演示文稿并展示其工作 在UAB的一个正在进行的工作研讨会上。实习生的进度以一年两次的书面报告和 与每一位实习生和导师一起与项目联席主任会面。几项创新 自四年前该计划开始实施以来就已经建立了。其中包括月刊 基因组医学会议和创业实践；后者利用强者 HudsonAlpha与HudsonAlpha园区托管的生物技术公司的关系。在……里面 为了提高我们招募MD的能力，我们与UAB部门建立了关系 外科和医学部，这两个都有计划，使居民能够追求 或在他们的培训过程中进行更多年的研究。我们还增加了一堂入门课 基因医学基础系列，以确保所有受训人员都具备基本技能 基因组医学，例如，包括数据管理和共享。所要求的教育 研究的严谨性和可重复性也是一个新的补充。我们加强了外展工作。 加强招募少数族裔加入该计划。这包括利用我们拥有的关系 通过我们的R25 DAP计划与阿拉巴马州历史上的黑人学院和大学建立联系 《基因组医学(Sure-GM)暑期本科生体验》和《Muscogee(Creek)》 国家。最后，我们采用了最初开发的项目评估方法--通用汽车 提供对我们的T32基因组医学培训计划的正式评估。