UAB-HudsonAlpha Genomic Medicine Training Program

项目概要 UAB-HudsonAlpha 基因组医学培训计划成立于四年前，旨在培训 将遗传学和基因组学融入医疗实践的领导者。我们已经招募了研究员 参加定制教育培训并接受指导的医学博士、博士或药学博士学位 在 UAB 或 HudsonAlpha 进行研究。教育计划基于一套使学生具备能力的能力 具有成为独立基因组医学研究员的知识和技能的实习生。每位练习生 还完成了基因组医学实习，提供了接触诊所和临床实验室的机会， 教育推广项目、探索创业职业机会的机会，以及 负责任的研究行为以及研究的严谨性和可重复性方面的培训。学员们 作为个性化研究的一部分，在 60 名项目教师之一的主持下开展指导性研究 发展计划。 UAB 和 HudsonAlpha 的会议包括研究研讨会、基因组 测序病例审查会议、分子肿瘤委员会和每月一次的基因组医学 会议，为所有学员提供基础和共同平台。所有学员参加年度培训 NHGRI 培训会议并展示海报或平台演示并展示他们的工作 在 UAB 举办的“正在进行的工作”研讨会上。通过每半年一次的书面报告来监测学员的进展情况 与每位学员和导师以及项目联合主任举行会议。多项创新 自四年前该计划启动以来一直在实施。其中包括每月 基因组医学会议和创业实习；后者利用了强大的力量 HudsonAlpha 与 HudsonAlpha 园区内的生物技术公司的关系。在 为了提高我们招募医学博士的能力，我们与 UAB 部门建立了合作关系 外科和医学系，这两个部门都有让居民能够追求两种学位的项目 或在培训过程中进行多年的研究。我们还添加了入门讲座 基因组医学基础知识系列，以确保所有学员都具备基因组医学的基本技能 基因组医学，包括数据管理和共享等。所需的教育程度 研究的严谨性和可重复性也是一个新的补充。我们加强了外展工作 加强招募少数族裔参与该计划。这包括利用我们拥有的关系 通过我们的 R25 DAP 计划与阿拉巴马州历史悠久的黑人学院和大学合作 “基因组医学暑期本科生体验 (SURE-GM)” 和 Muscogee (Creek) 民族。最后，我们采用了最初为 SURE-GM 开发的项目评估方法 对我们的 T32 基因组医学培训计划进行正式评估。

Project Summary The UAB-HudsonAlpha Genomic Medicine Training Program was established four years ago to train leaders in the integration of genetics and genomics into medical practice. We have recruited fellows with an MD, PhD, or PharmD degree who participate in customized educational training and pursue mentored research at UAB or HudsonAlpha. The educational plan is based on a set of competencies that equip the trainee with the knowledge and skill set to be an independent genomic medicine researcher. Each trainee also completes a genomic medicine practicum that provides exposure to clinics and clinical laboratories, an educational outreach project, an opportunity to explore entrepreneurship career opportunities, and training in the responsible conduct of research and rigor and reproducibility in research. The trainees carry out mentored research under the auspices of one of 60 program faculty, as part of an individualized development plan. Conferences at UAB and HudsonAlpha include research seminars, genome sequencing case review conferences, a molecular tumor board, and a monthly genomic medicine meeting, which provide a foundation and common platform for all trainees. All trainees attend the annual NHGRI training conference and present either posters or platform presentations and present their work at a Work in Progress seminar at UAB. Trainee progress is monitored in biannual written reports and meetings with each trainee and mentor together with the program co-directors. Several innovations have been instituted since the inception of the program four years ago. These include the monthly genomic medicine conference and the entrepreneurship practicum; the latter leverages the strong relationship of HudsonAlpha with biotechnology companies hosted on the HudsonAlpha campus. In order to increase our ability to recruit MDs, we have forged relationships with the UAB Department of Surgery and Department of Medicine, both of which have programs that enable residents to pursue two or more years of research during the course of their training. We have also added an introductory lecture series on the basics of genomic medicine to ensure that all trainees are equipped with basic skills in genomic medicine, including, for example, data management and sharing. The required education in Rigor and Reproducibility in Research is also a new addition. We have strengthened our outreach efforts to enhance the recruitment of minorities to the program. This includes leveraging relationships we have forged with Historically Black Colleges and Universities in Alabama through our R25 DAP program “Summer Undergraduate Experience in Genomic Medicine (SURE-GM)” and with the Muscogee (Creek) Nation. Finally, we have adapted a program evaluation approach initially developed for SURE-GM to provide formal evaluation of our T32 Genomic Medicine Training Program.