UAB-HudsonAlpha Genomic Medicine Training Program

UAB-HudsonAlpha 基因组医学培训计划

• 批准号: 10403651
• 负责人: Gregory Stefan Barsh
• 金额: $ 31.68万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-06-01 至 2026-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10403651
• 关键词: Genomic medicine; Training Programs

Project Summary The UAB-HudsonAlpha Genomic Medicine Training Program was established four years ago to train leaders in the integration of genetics and genomics into medical practice. We have recruited fellows with an MD, PhD, or PharmD degree who participate in customized educational training and pursue mentored research at UAB or HudsonAlpha. The educational plan is based on a set of competencies that equip the trainee with the knowledge and skill set to be an independent genomic medicine researcher. Each trainee also completes a genomic medicine practicum that provides exposure to clinics and clinical laboratories, an educational outreach project, an opportunity to explore entrepreneurship career opportunities, and training in the responsible conduct of research and rigor and reproducibility in research. The trainees carry out mentored research under the auspices of one of 60 program faculty, as part of an individualized development plan. Conferences at UAB and HudsonAlpha include research seminars, genome sequencing case review conferences, a molecular tumor board, and a monthly genomic medicine meeting, which provide a foundation and common platform for all trainees. All trainees attend the annual NHGRI training conference and present either posters or platform presentations and present their work at a Work in Progress seminar at UAB. Trainee progress is monitored in biannual written reports and meetings with each trainee and mentor together with the program co-directors. Several innovations have been instituted since the inception of the program four years ago. These include the monthly genomic medicine conference and the entrepreneurship practicum; the latter leverages the strong relationship of HudsonAlpha with biotechnology companies hosted on the HudsonAlpha campus. In order to increase our ability to recruit MDs, we have forged relationships with the UAB Department of Surgery and Department of Medicine, both of which have programs that enable residents to pursue two or more years of research during the course of their training. We have also added an introductory lecture series on the basics of genomic medicine to ensure that all trainees are equipped with basic skills in genomic medicine, including, for example, data management and sharing. The required education in Rigor and Reproducibility in Research is also a new addition. We have strengthened our outreach efforts to enhance the recruitment of minorities to the program. This includes leveraging relationships we have forged with Historically Black Colleges and Universities in Alabama through our R25 DAP program “Summer Undergraduate Experience in Genomic Medicine (SURE-GM)” and with the Muscogee (Creek) Nation. Finally, we have adapted a program evaluation approach initially developed for SURE-GM to provide formal evaluation of our T32 Genomic Medicine Training Program.

项目摘要 UAB-HudsonAlpha基因组医学培训项目成立于四年前， 将遗传学和基因组学整合到医疗实践中的领导者。我们招募了一些研究员， MD，PhD或PharmD学位，参加定制的教育培训并接受指导 在UAB或HudsonAlpha进行研究。该教育计划是基于一套能力，装备 培训生的知识和技能，是一个独立的基因组医学研究人员。每个学员 还完成了基因组医学实习，提供接触诊所和临床实验室， 一个教育推广项目，一个探索创业职业机会的机会， 在负责任的研究行为以及研究的严谨性和可重复性方面进行培训。学员 在60个项目教师之一的主持下进行指导研究，作为个性化研究的一部分。 发展规划UAB和HudsonAlpha的会议包括研究研讨会，基因组 测序病例审查会议，分子肿瘤委员会，以及每月的基因组医学 会议为所有学员提供了一个基础和共同的平台。所有学员都参加了 NHGRI培训会议，并提出海报或平台介绍，并介绍他们的工作 在UAB的一个工作进展研讨会上。在一年两次的书面报告中监测受训人员的进展情况， 与每个学员和导师以及项目共同负责人会面。若干创新 自四年前该计划成立以来，就一直在制定。其中包括每月 基因组医学会议和创业实习;后者利用强大的 HudsonAlpha与HudsonAlpha校园内托管的生物技术公司的关系。在 为了提高我们招募MD的能力，我们与UAB部门建立了关系， 外科和内科，这两个部门都有计划，使居民能够追求两个 或在培训过程中进行多年的研究。我们还增加了一个介绍性讲座 关于基因组医学基础知识的系列课程，以确保所有学员都具备以下基本技能： 基因组医学，包括例如数据管理和共享。所需的教育 研究中的严谨性和再现性也是一个新的补充。我们加强了外联工作， 加强对少数民族的招募。这包括利用我们拥有的关系 通过我们的R25 DAP计划与亚拉巴马的历史黑人学院和大学共同打造 “夏季本科生在基因组医学的经验（SURE-GM）”和与Muscogee（溪） 民族最后，我们采用了最初为SURE-GM开发的项目评估方法， 提供我们的T32基因组医学培训计划的正式评估。