Kidney Undergraduate Research Experience (KURE)

摘要 在肾脏疾病研究中，训练有素的生物医学研究人员的数量正在不断减少。它是 当务之急是，我们必须启动创新计划，重振下一代肾脏研究人员。 创新和创造性的研究人员需要在我们的高度理解中前进 肾脏疾病中观察到的复杂的病理生理学。今天，肾脏疾病的增加速度比 除了肾脏替代疗法之外，几乎没有其他治疗选择。我们只有很少的基本 受过肾脏疾病研究培训的科学家和/或临床科学家。此R25提案的总体目标是 是在UAB建立专门针对肾脏的夏季本科生研究体验 以新颖的策略进行疾病研究，使学生能够成为终身研究人员。 肾脏本科生研究体验(KURE)计划的新战略将包括 对本科生进行重点培训，以促进批判性思维、沟通和 亲身实践肾脏研究技能以及参与肾脏疾病的病理生理学-所有这些 策略的中心是学生对基础和转化性肾脏研究的认同感。 KURE计划将使我们的学者接触到科学思维和交流的严谨和深度 这些技能将使他们做好准备，在其职业生涯中为医学进步做出贡献。新的战略是 需要让学生参与并增强他们在肾脏疾病研究中的终身职业生涯。KURE计划 将有助于扩大致力于肾脏研究的科学家和医生-科学家队伍，目前 在美国的萎缩，以及拓宽和进一步加强肾脏学术研究的文化 UAB学术医疗中心的疾病。这将通过他们对肾脏的参与来实现 相声研讨会(KCTW)系列，将从参加为期1天的团队科学、网络和 交流退却以及对肾脏生理和病理的批判性思维的发展 病理生理学以肾病学家和肾脏疾病患者的阴影经历结束。 此外，KURE学者将参加我们的持续职业指导计划，该计划将利用近同行 在夏季和通过KURE Facebook、LinkedIn进行面对面互动的导师 网络和《循环中的时事通讯》。

ABSTRACT The numbers of highly trained biomedical investigators in kidney disease research is ever dwindling. It is imperative that we initiate innovative schemes to reinvigorate the next generation of renal researchers. Innovative and creative research investigators are required to move forward in our understanding of the highly complex pathophysiology observed in kidney disease. Kidney disease is increasing today at higher rates than ever before with few treatment options other than renal replacement therapy. We have very few basic scientists and/or clinician scientists trained in kidney disease research. The overall goal of this R25 proposal is to estblish a focused summer undergraduate research experience at UAB exclusively on kidney disease research with novel strategies to engage and empower students to be life-long researchers. The novel strategy of the Kidney Undergraduate Research Experience (KURE) program will incorporate focused training of undergraduate students to foster development of critical thinking, communication, and hands on kidney research skills as well as engagement in the pathophysiology of kidney disease—all strategies are centered on the student gaining an identification with basic and translational kidney research. The KURE program will expose our scholars to the rigor and depth of scientific thinking and communication skills that will prepare them to contribute to medical advances throughout their careers. Novel strategies are needed to engage and empower students for life-long careers in kidney disease research. The KURE program will help to expand the scientist and physician-scientist workforce dedicated to renal research that is currently shrinking in the US, as well as broaden and further enhance the culture of academic investigation of kidney disease at the UAB academic medical center. This will be accomplished by their participation in the Kidney Cross-Talk Workshop (KCTW) series that will start with participation in a 1-day team science, networking, and communications retreat as well as the development of critical thinking about kidney physiology and pathophysiology ending with shadowing experiences with nephrologists and patients with kidney disease. Further, KURE scholars will be enrolled in our Continuing Career Mentorship program that will utilize near peer mentorship to interact in-person during the summer as well as through the KURE Facebook, LinkedIn networking, and the “newsletter” In the Loop.