Kidney Undergraduate Research Experience (KURE)

摘要 肾脏疾病研究中训练有素的生物医学研究人员的数量正在不断减少。是 我们必须启动创新计划，以重振下一代肾脏研究人员。 创新和创造性的研究人员需要向前迈进，在我们的高度理解 肾脏疾病中观察到的复杂病理生理学。今天肾脏疾病的增长率高于 除了肾脏替代疗法之外，几乎没有其他治疗选择。我们几乎没有 接受过肾病研究培训的科学家和/或临床科学家。本R25提案的总体目标 是在UAB建立一个专注于肾脏的暑期本科研究经验 疾病研究与新的战略，使学生参与和授权终身研究人员。 肾脏本科生研究经验（KURE）计划的新策略将包括 重点培养本科生，以促进批判性思维，沟通， 动手肾脏研究技能以及参与肾脏疾病的病理生理学-所有 战略的重点是学生获得与基础和转化肾脏研究的认同。 KURE计划将使我们的学者了解科学思维和交流的严谨性和深度 这些技能将使他们在整个职业生涯中为医学进步做出贡献。新的战略是 需要让学生参与并赋予他们终身从事肾脏疾病研究的权利。KURE计划 将有助于扩大目前致力于肾脏研究的科学家和医生科学家队伍， 缩小在美国，以及扩大和进一步提高文化学术研究的肾脏 UAB学术医疗中心的疾病。这将通过他们参与肾脏来实现 相声工作坊（KCTW）系列，将开始参与为期1天的团队科学，网络， 通信务虚会以及对肾脏生理学的批判性思维的发展， 病理生理学，以跟随肾病学家和肾病患者的经验结束。 此外，KURE学者将参加我们的持续职业导师计划，该计划将利用近同行 导师在夏季期间亲自互动，以及通过KURE Facebook，LinkedIn 网络，和“通讯”在循环。

ABSTRACT The numbers of highly trained biomedical investigators in kidney disease research is ever dwindling. It is imperative that we initiate innovative schemes to reinvigorate the next generation of renal researchers. Innovative and creative research investigators are required to move forward in our understanding of the highly complex pathophysiology observed in kidney disease. Kidney disease is increasing today at higher rates than ever before with few treatment options other than renal replacement therapy. We have very few basic scientists and/or clinician scientists trained in kidney disease research. The overall goal of this R25 proposal is to estblish a focused summer undergraduate research experience at UAB exclusively on kidney disease research with novel strategies to engage and empower students to be life-long researchers. The novel strategy of the Kidney Undergraduate Research Experience (KURE) program will incorporate focused training of undergraduate students to foster development of critical thinking, communication, and hands on kidney research skills as well as engagement in the pathophysiology of kidney disease—all strategies are centered on the student gaining an identification with basic and translational kidney research. The KURE program will expose our scholars to the rigor and depth of scientific thinking and communication skills that will prepare them to contribute to medical advances throughout their careers. Novel strategies are needed to engage and empower students for life-long careers in kidney disease research. The KURE program will help to expand the scientist and physician-scientist workforce dedicated to renal research that is currently shrinking in the US, as well as broaden and further enhance the culture of academic investigation of kidney disease at the UAB academic medical center. This will be accomplished by their participation in the Kidney Cross-Talk Workshop (KCTW) series that will start with participation in a 1-day team science, networking, and communications retreat as well as the development of critical thinking about kidney physiology and pathophysiology ending with shadowing experiences with nephrologists and patients with kidney disease. Further, KURE scholars will be enrolled in our Continuing Career Mentorship program that will utilize near peer mentorship to interact in-person during the summer as well as through the KURE Facebook, LinkedIn networking, and the “newsletter” In the Loop.