Community-led Action Research in Oncology: Pandemic-appropriate Radiotherapy Innovations Evaluated for LMICs

社区主导的肿瘤学行动研究：针对中低收入国家评估适合流行病的放射治疗创新

• 批准号: 10380931
• 负责人: Steven D Leach
• 金额: $ 17.18万
• 依托单位: DARTMOUTH COLLEGE
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-01 至 2021-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10380931
• 关键词: 2019-nCoV; Action Research; Address; Back; COVID-19; COVID-19 pandemic; Cancer Center; Cancer Control; Caribbean region; Cities; Clinic; Clinical; Communities; Community Healthcare; Comprehensive Cancer Center; Consensus; Country; Data Collection; Development; Disease; Ensure; Evaluation; Future; Goals; Health; Healthcare; Honduras; Hygiene; Infection prevention; International; Knowledge; Latin America; Latin American; Maintenance; Malignant Neoplasms; Manuals; Medical Oncologist; Medical Oncology; Medical Societies; Mentors; Methods; Morbidity - disease rate; New Hampshire; Norris Cotton Cancer Center; Oncology; Participant; Patients; Phase; Physicians; Preparation; Procedures; Process; Quality of Care; Radiation Oncology; Radiation therapy; Reporting; Research; Research Technics; Resources; Risk; Route; Safety; Schedule; Scientist; Series; Source; Teleconferences; Testing; United States National Institutes of Health; Virus; base; cancer care; cancer therapy; care outcomes; community based participatory research; community center; cost; design; evidence base; experience; infection risk; innovation; insight; interest; low and middle-income countries; mortality; multidisciplinary; multimodality; operation; pandemic disease; public health emergency; research study; response; safety and feasibility; safety testing; ventilation

ABSTRACT Community-led Action Research in Oncology – Pandemic-appropriate Radiotherapy Innovations Evaluated for LMICs (CLARO PARTE for LMICs) This application is being submitted in response to the Notice of Special Interest (NOSI) identified as NOT-CA- 21-033. This participatory action research (PAR) study will assess radiotherapy (RT) innovations in partnership with oncology professionals in Latin America and the Caribbean (LAC). We will leverage global experience and relationships of the Community-led Action Research in Oncology (CLARO) global oncology research team at Norris Cotton Cancer Center (NCCC) and involve RT professionals throughout LAC in evaluating “frugal innovations,” which were developed during the COVID-19 pandemic and are defined as the creation of unexpected solution that are simpler and disruptive alternatives to provide adequate healthcare within reach of everyone (Tran et al. 2016). Our overall goal is to identify frugal innovations and evaluate them for safety, efficiency, quality, feasibility, acceptability, and potential potency, to assess adaptability for use in future pandemics, or other public health emergencies. Phase 1 involves convening LAC RT professionals in a Project ECHOTM (Extension for Community Healthcare Outcomes) tele-mentoring partnership to share frugal innovations devised by their clinics during the COVID-19 pandemic. The Latin-American and Caribbean Society for Medical Oncology (SLACOM) will facilitate a panel of RT professionals joining the teleconferences. In Phase 2, physicians and scientists experienced in radiation oncology and innovation will evaluate innovations for effects on virus control, maintenance of clinical operations, and continuance of quality care by a multidisciplinary team applying international standards. The innovations that meet standards will advance to Phase 3, returning to the panel of LAC RT professionals where participants will engage in a Delphi consensus- building process to assess feasibility, acceptability within their setting, and potential potency. Relying on highly participatory and iterative processes, which are the hallmarks of Participatory Action Research (PAR), we will move from data collection and reflection to action and improvement, leveraging relationships between NCCC’s CLARO and SLACOM. Ultimately, we will develop a manual of scalable frugal RT innovations suitable for LMICs in a pandemic. Innovations will be organized topically: routing, hygiene, ventilation, PPE, and scheduling, etc. and further organized in matrixes by high/low impact and high/low cost.

摘要 社区主导的肿瘤学行动研究-适合大流行的放射治疗创新 针对中低收入国家进行了评价（针对中低收入国家的评估部分） 本申请是为了响应被标识为NOT-CA的特别利益通知（NOSI）而提交的- 21-033.这项参与性行动研究（PAR）研究将评估放射治疗（RT）的合作创新 与拉丁美洲和加勒比地区（LAC）的肿瘤学专业人士合作。我们将利用全球经验， 社区领导的肿瘤学行动研究（Community led Action Research in Oncology，简称CAMO）全球肿瘤学研究团队的关系， Norris Cotton癌症中心（NCCC），并让整个LAC的RT专业人员参与评估“节俭” 创新，”这是在COVID-19大流行期间开发的，被定义为创造 意想不到的解决方案，是更简单和破坏性的替代方案， 所有人（Tran et al. 2016）。我们的总体目标是识别节约创新并评估其安全性， 效率、质量、可行性、可接受性和潜在效力，以评估未来使用的适应性 流行病或其他突发公共卫生事件。第1阶段涉及在项目中召集LAC RT专业人员 ECHOTM（社区医疗保健成果扩展）远程指导合作伙伴关系， 他们的诊所在COVID-19大流行期间设计的创新。拉丁美洲和加勒比 医学肿瘤学会（SLACOM）将促进一个RT专业人员小组参加电话会议。 在第2阶段，在放射肿瘤学和创新方面经验丰富的医生和科学家将评估 创新对病毒控制的影响，维持临床操作，并通过 采用国际标准的多学科团队。符合标准的创新将推进到 第3阶段，返回LAC RT专业人员小组，参与者将参与德尔菲共识- 建立过程，以评估可行性，在其设置的可接受性，和潜在的潜力。高度依赖 参与和迭代过程，这是示范行动研究（PAR）的标志，我们将 从数据收集和反思转向行动和改进，利用NCCC之间的关系 陆军和海军司令部。最终，我们将开发一个可扩展的节俭RT创新手册， LMIC在大流行中。创新将按主题组织：路由，卫生，通风，PPE， 调度等，并进一步按照高/低影响和高/低成本组织成矩阵。