Administrative supplement for Early Drug Development Opportunity Program (EDDOP)

早期药物开发机会计划 (EDDOP) 的行政补充

基本信息

  • 批准号:
    10677500
  • 负责人:
  • 金额:
    $ 7.5万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2022
  • 资助国家:
    美国
  • 起止时间:
    2022-09-01 至 2024-11-30
  • 项目状态:
    已结题

项目摘要

ABSTRACT This proposal addresses Dartmouth Cancer Center’s (DCC) ability to conduct and participate in cancer early phase clinical trials through the Experimental Therapeutics Clinical Trials Network (ETCTN) of the National Cancer Institute (NCI). It serves as a comprehensive response to the NCI’s P30 Cancer Center Support Grant Administrative Supplement, to NCI-designated Cancer Centers previously participating in Create Access to Targeted Cancer Therapy for Underserved Populations (CATCH-UP), to promote continued collaboration with CTEP’s ETCTN under funding opportunity PA-20-272. DCC’s objectives as an NCI-designated comprehensive cancer center are aligned with ETCTN’s goals to conduct early phase clinical treatment trials across a broad range of cancers and diverse patient populations, with an emphasis on rare diseases. DCC was approved through peer review for the NCI Cancer Center’s Early Phase Clinical Research component of NCI Center Grants. Dartmouth is a Lead Academic Participating Site in the NCI National Clinical Trials Network. We currently are not affiliated with any ETCTN UM1 grantees that are funded to conduct studies of NCI-IND agents with a phase 1, and more recently also with phase 2, emphasis. Our proposal utilizes a pre-existing and functioning cadre of established inter- and multidisciplinary investigators at DCC, The Geisel School of Medicine at Dartmouth (Geisel), Dartmouth Health (DH), and the Thayer School of Engineering at Dartmouth, which share common clinical, basic science and clinical translational research interests in cancer treatment and imaging. We have core laboratories and an infrastructure that supports the conduct of a wide spectrum of correlative science studies typically associated with early phase trials and basic research in cancer biology, immunology, and imaging. As an academic NCI-designated comprehensive cancer center, we are well-positioned to provide scientific leadership in developing and conducting innovative early phase studies of anti-cancer agents held under CTEP’s IND, as well as substantial numbers of patients eligible for accrual to clinical trials conducted across the entire ETCTN.
摘要

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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Steven D Leach其他文献

Steven D Leach的其他文献

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{{ truncateString('Steven D Leach', 18)}}的其他基金

Developing ATAC-array as a novel epigenetic biomarker to guide personalized therapy in pancreatic cancer
开发 ATAC 阵列作为新型表观遗传生物标志物来指导胰腺癌的个性化治疗
  • 批准号:
    10512502
  • 财政年份:
    2022
  • 资助金额:
    $ 7.5万
  • 项目类别:
P30 Administrative Supplement to Cancer Center Support Grant to Strengthen NCI-Supported Community Outreach Capacity through Community Health Educators of the National Outreach Network.
P30 癌症中心支持补助金的行政补充,旨在通过国家外展网络的社区健康教育者加强 NCI 支持的社区外展能力。
  • 批准号:
    10370916
  • 财政年份:
    2021
  • 资助金额:
    $ 7.5万
  • 项目类别:
Community-led Action Research in Oncology: Pandemic-appropriate Radiotherapy Innovations Evaluated for LMICs
社区主导的肿瘤学行动研究:针对中低收入国家评估适合流行病的放射治疗创新
  • 批准号:
    10380931
  • 财政年份:
    2021
  • 资助金额:
    $ 7.5万
  • 项目类别:
Comprehensive genetic dissection of druggable KRAS targets
可药物 KRAS 靶点的全面基因剖析
  • 批准号:
    9476973
  • 财政年份:
    2016
  • 资助金额:
    $ 7.5万
  • 项目类别:
Comprehensive genetic dissection of druggable KRAS targets
可药物 KRAS 靶点的全面基因剖析
  • 批准号:
    9922888
  • 财政年份:
    2016
  • 资助金额:
    $ 7.5万
  • 项目类别:
Comprehensive genetic dissection of druggable KRAS targets
可药物 KRAS 靶点的全面基因剖析
  • 批准号:
    9080884
  • 财政年份:
    2016
  • 资助金额:
    $ 7.5万
  • 项目类别:
Functional Evaluation of Human Pancreatic Cancer Genes in a Zebrafish System
斑马鱼系统中人类胰腺癌基因的功能评估
  • 批准号:
    8464656
  • 财政年份:
    2013
  • 资助金额:
    $ 7.5万
  • 项目类别:
High resolution and single cell analyses of PanIN initiation and progression
PanIN 起始和进展的高分辨率单细胞分析
  • 批准号:
    8248212
  • 财政年份:
    2011
  • 资助金额:
    $ 7.5万
  • 项目类别:
High resolution and single cell analyses of PanIN initiation and progression
PanIN 起始和进展的高分辨率单细胞分析
  • 批准号:
    8095001
  • 财政年份:
    2011
  • 资助金额:
    $ 7.5万
  • 项目类别:
Confocal imaging resources for the JHU Zebrafish Center
JHU 斑马鱼中心的共焦成像资源
  • 批准号:
    7794133
  • 财政年份:
    2010
  • 资助金额:
    $ 7.5万
  • 项目类别:

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