2022 Bacterial Cell Surfaces GRC/GRS

2022 细菌细胞表面GRC/GRS

• 批准号: 10374358
• 负责人: Michael Stephen Trent
• 金额: $ 0.5万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-06-14 至 2023-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10374358
• 关键词: Animals; Anti-Bacterial Agents; Area; Atmosphere; Award; Bacteria; Bacterial Drug Resistance; Bacterial Physiology; Basic Science; Benign; Biochemistry; Biological Models; Biological Process; Biology; Biophysics; Career Choice; Cell division; Cell surface; Cells; Cellular biology; Climate; Columbidae; Communities; Development; Disease; Ensure; Experimental Models; Feedback; Fertilization; Fostering; Generations; Genetic; Health; Hour; Human; Image; Knowledge; Medical; Mental Health; Microbe; Mission; Modeling; Molecular; Molecular Genetics; Morphogenesis; Multi-Drug Resistance; Participant; Pathogenesis; Pharmacotherapy; Plants; Postdoctoral Fellow; Process; Research; Research Personnel; Resort; Science; Scientist; Seeds; Stress Response Signaling; Surface; Travel; United States National Institutes of Health; Vaccine Therapy; Work; antimicrobial; bacterial community; biophysical techniques; career; cell envelope; design; diversity and inclusion; educational atmosphere; gender diversity; graduate student; host-microbe interactions; improved; innovation; insight; interest; meetings; microbial community; microbiome; microbiota; microorganism; minority trainee; multi-drug resistant pathogen; new technology; novel diagnostics; novel therapeutics; novel vaccines; pathogen; pathogenic bacteria; peer; posters; programs; resistant strain; skills; structural biology; success; symposium; vaccine development

ABSTRACT This proposal seeks support for the 24th Gordon Research Conference (GRC) on Bacterial Cell Surfaces, the only meeting that connects cutting-edge research on cell envelope biology to the medically important downstream consequences of the bacterial cell surface. The 2022 meeting will be held June 26-July 1, 2022 at Mount Snow Resort, West Dover, VT and will have an associated Gordon Research Seminar (GRS). The meeting will cover topics that are of great interest to the biomedical community, especially in the current climate of the increased threat of multi-drug resistant pathogens, the need for novel vaccines, and the influence of the microbiome on human health. This GRC presents a diverse program in topics, model systems, and approaches combining biochemistry, molecular genetics, structural biology, cell biology, biophysics, imaging and modeling. There will be 9 sessions encompassing: (1) Exploring the Bacterial Cell Envelope; (2) Modifying the Bacterial Surface; (3) Cell Division and Morphogenesis; (4) Stress Responses and Signaling Across the Cell Envelope; (5) Mechanisms of Surface Recognition; (6) Transport through the Envelope; (7) Type VI and Type VII Secretion; (8) How the Surface Influences Bacterial Communities; and (9) Biophysical Methods to Improve Antimicrobial Therapies. The conference will focus on the latest, largely unpublished, and most exciting research on the assembly and function of the bacterial cell surface. We have selected a group of leading scientists, including a number of rising stars, and have closely considered seniority, gender, and diversity. To enhance the 2022 meeting, we have included roundtable discussions for junior scientists to engage with leaders of the field, the GRC Power Hour to examine issues of inclusion and diversity, and additional travel awards to support minority trainees. Additionally, we have further integrated the highly successful GRS for postdocs and graduate students with the GRC. Participants of the GRS will select 2 talks from the GRS for presentation at the GRC and the GRS co-chairs will present a summary of their meeting at the GRC opening. The traditional format of GRC meetings, with programmed discussion sessions and opportunities for informal gatherings in the afternoons and evenings, conveys a collegial atmosphere where interactions between attendees of all career stages are easily attained. The topics of this multifaceted conference are of practical interest to the biomedical community, and the mission of the NIH as it provides a platform for nucleating approaches to antibacterial strategies, vaccine development, and study of host-microbe interactions.

摘要 这项建议寻求支持第24届戈登研究会议（GRC）的细菌细胞表面， 这是唯一一次将细胞包膜生物学的前沿研究与医学上重要的 细菌细胞表面的下游后果。2022年会议将于2022年6月26日至7月1日在 雪山度假村，西多佛，佛蒙特州，并将有一个相关的戈登研究研讨会（GRS）。的 会议将涵盖生物医学界非常感兴趣的主题，特别是在当前的环境下 多重耐药病原体的威胁增加，对新型疫苗的需求，以及 微生物对人类健康的影响这个GRC提出了一个主题，模型系统和方法的多样化计划 结合生物化学、分子遗传学、结构生物学、细胞生物学、生物物理学、成像和建模。 将有9个会议，包括：（1）探索细菌细胞包膜;（2）修改细菌 表面;（3）细胞分裂和形态发生;（4）应激反应和跨细胞膜的信号传导; (5)表面识别机制;（6）通过包膜转运;（7）VI型和VII型分泌; (8)表面如何影响细菌群落;以及（9）改善抗微生物性的生物物理方法 治疗会议将重点关注最新的，大部分未发表的，最令人兴奋的研究， 细菌细胞表面的组装和功能。我们挑选了一批顶尖科学家，包括一位 许多后起之秀，并密切考虑资历，性别和多样性。为了增强2022年 会议，我们已经包括圆桌讨论，为年轻的科学家与该领域的领导者， GRC Power Hour将研究包容性和多样性问题，以及支持少数族裔的额外旅行奖励 实习生此外，我们还为博士后和研究生进一步整合了非常成功的GRS 在GRC。参加者将从研究组中选出两个讲座，分别在研究组及研究组进行 联合主席将在GRC开幕式上提交会议摘要。GRC会议的传统形式， 安排了讨论会，下午和晚上有机会举行非正式聚会， 传达了一种学院式的氛围，在这种氛围中，各个职业阶段的参与者之间的互动很容易实现。 这个多方面的会议的主题是实际利益的生物医学界，和使命 因为它为抗菌策略，疫苗开发， 和宿主-微生物相互作用的研究。