Cancer Adoptive Cell Therapy (Can-ACT) Network Coordinating Center at Mayo Clinic
Cancer Adoptive Cell Therapy (Can-ACT) Network Coordinating Center at Mayo Clinic
批准号:
10730805
负责人:
Yan W. Asmann
金额:
$48.03万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2023
资助国家:
美国
项目状态:
未结题
起止时间:
2023-09-01 至 2028-08-31
关键词:
Administrative CoordinationAdministrative SupplementAdoptive Cell TransfersAdultAnimal ModelAreaBioinformaticsBiologicalBiological Specimen BanksBiometryCancer CenterCell TherapyCellsChildhoodClinicClinicalClinical ResearchClinical TrialsCollaborationsCollectionCommunicationCommunitiesDataData CollectionData Management ResourcesData ScienceData SecurityDevelopmentElementsFoundationsFundingHumanIndividualIndustryInfrastructureInstitutionLeadershipLearningMalignant NeoplasmsMulticenter TrialsOncologyPatientsPoliciesPositioning AttributeProcessReagentResearchResearch PersonnelResourcesSolid NeoplasmSpecimenStandardizationStructureTestingTherapeuticTherapeutic AgentsTranslational ResearchWorkanticancer researchbiobankclinical translationdata harmonizationdata managementdata sharingdata submissiondesignearly phase clinical trialelectronic dataexperienceinnovationinterestmanufacturemeetingsmembernovel therapeuticsoperationpre-clinicalpre-clinical researchpreclinical developmentpreclinical studyprogramsresearch studysynergismtreatment responseweb siteworking group
中文摘要
项目摘要/摘要-网络协调中心
英文摘要
PROJECT SUMMARY/ABSTRACT – NETWORK COORDINATING CENTER
The Network Coordinating Center (NCC) will facilitate and be responsible for network-wide coordination and
harmonization of scientific and clinical needs of the funded UG3/UH3 centers comprising the Cancer Adoptive
Cellular Therapeutics (Can-ACT) Network. The Network Coordinating Center at Mayo Clinic (NCC-MC) will
serve as the administrative hub and coordinating center for all network-related trials and projects. This will
include multiple aspects of the functioning of this network, including the administrative and scientific
coordination of the Can-ACT Network. The administrative coordination will include (a) providing leadership and
facilitating interactions across the network, (b) providing administrative infrastructure to support the activities of
the Can-ACT Network, and (c) the coordination of the restricted collaborative funds and administrative
supplements for the network. Scientific coordination of this network will include several different critical
components, including (a) identifying and establishing strategies for facilitating reagent and specimen sharing,
(b) identification and harmonization of process development and manufacturing steps for cell product
management and utilization for the functioning of the network between centers and the ICN Core, (c)
biostatistical support and collaboration for preclinical and clinical research studies and centralized data
management and shared data governance, and (d) bioinformatics and data science support and collaboration.
The infrastructure, expertise, and experience of the individuals at Mayo Clinic with national coordination of
translational and clinical research is extensive, making this group well-positioned to function as an outstanding
coordinating center for the Can-ACT Network. The leadership of this proposed coordinating center brings with
them complementary and deep experience and background across these key aims, and they have worked
extensively with multi-institutional trials, consortia, and networks as well as cooperative groups in research
leadership, trial coordination and implementation, data structures, and importantly development of SOPs and
guidance for newly formed collaborative research networks across multiple institutions. Beyond the experience
and expertise, the NCC-MC also leverages institutional infrastructure and resources to adapt and evolve as the
Can-ACT Network develops and grows through the expected and necessary collaborations across all
UG3/UH3 centers and project leaders.
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会议论文
Bioinformatics, Biostatistics, and Data Management Core
-
批准号:10407942
-
项目类别:
-
资助金额:$55.43万
-
财政年份:2021
-
负责人:Yan W. Asmann
-
依托单位:
Bioinformatics, Biostatistics, and Data Management Core
-
批准号:10667458
-
项目类别:
-
资助金额:$55.11万
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财政年份:2021
-
负责人:Yan W. Asmann
-
依托单位:
Building the Foundation of Epigenomics Roadmaps
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批准号:9131859
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项目类别:
-
资助金额:$10.0万
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财政年份:2014
-
负责人:Yan W. Asmann
-
依托单位:
Building the Foundation of Epigenomics Roadmaps
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批准号:8812480
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项目类别:
-
资助金额:$31.3万
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财政年份:2014
-
负责人:Yan W. Asmann
-
依托单位:
海外基金