Older Adult Social Participation, Gender, and Cognitive Decline
Older Adult Social Participation, Gender, and Cognitive Decline
批准号:
10704851
负责人:
Eric Vogelsang
金额:
$18.66万
依托单位国家:
美国
项目类别:
财政年份:
2023
资助国家:
美国
项目状态:
未结题
起止时间:
2023-08-15 至 2027-04-30
关键词:
AddressAgeAgingAlzheimer&aposs DiseaseAmericanAutomobile DrivingAwardCognitionCognitiveCommunitiesDementiaEducationElderlyEmpirical ResearchExerciseFamilyFamily memberFrequenciesFriendsGenderGoalsGrantHealthHealth and Retirement StudyHispanic-serving InstitutionImpaired cognitionIndividualInequalityLifeLife Cycle StagesLinkLiving ArrangementLongitudinal StudiesMeasuresMentorsMentorshipMexicanMotivationOutcomePatientsPlayPolicy MakerPublicationsRecommendationRecording of previous eventsReligiosityResearchResearch PersonnelRisk ReductionRoleSocial SciencesSocial supportSocializationSpecificityStandardizationStudentsSurveysTimeUnited States National Institutes of HealthValidity and ReliabilityWorkaging populationcognitive changecognitive functiondaily functioningdisorder riskexperiencegender disparityhigh risk drinkinghuman old age (65+)improvedmeetingsmiddle agepreventprotective effectpsychologicsex disparitysocialsocial cognitionsocial engagementsocial normtrendundergraduate studentvolunteer
中文摘要
项目摘要/摘要
寻找延缓或预防认知衰退和痴呆症的方法仍然是NIA的优先事项。作为这项工作的一部分
在工作中,越来越多的人认识到,社会参与和社区联系可能会降低风险
这些疾病。不幸的是,这项研究几乎没有提供各种社会活动是如何
可能会不同地预测认知能力下降。也很少有人调查老年人是如何社交的
参与或其与认知的关系可能因性别而不同。
与许多标准调查项目(例如,健康、教育)不同,在如何社交方面没有足够的一致性
参与度是通过社会调查来衡量的,并被用于实证研究。尤其是,使用社交媒体
参与度“概要衡量”(A)可能模糊认知和基础之间的区别联系
社交活动,以及(B)经常包括可以说不是“社会参与”的项目(例如,与
家庭成员)。这导致了两个限制:第一,不知道哪些社会活动--以及什么社会活动
这些活动的范围-正在推动任何联想。第二,很难将相似的结果进行比较
研究,引起了人们对效度和可靠性的担忧。
这个项目有三个目标。第一,我们将调查社会参与和老年人之间的关系
成年人的认知功能因社会活动而异。第二,我们将确定将特定社会联系起来的机制
活动对认知健康的影响。第三,我们将调查社会参与在多大程度上与
老年人的认知功能因性别而异。为了实现这些目标,我们将利用四个大的
具有全国代表性的老年人纵向研究。
Eric Vogelang博士,PI,有关于老年人社会参与和健康的既定出版记录
研究。该项目的合作者在认知功能研究方面拥有丰富的经验,
辅导和国立卫生研究院的拨款。在一家超级拉美裔服务机构(CSU-San Bernardino)工作,
该项目将为机会有限的学生提供研究经验。
拟议的研究将产生三个好处。首先,它将告知患者、从业者和政策制定者
希望延缓或防止认知衰退的发生。第二,它将使人们认识到对健康的影响
老年人社交活动中的性别不平等问题。第三,我们希望这项工作能够推动标准化
社会调查中的“社会参与”措施。
英文摘要
PROJECT SUMMARY/ABSTRACT
Identifying ways to delay or prevent cognitive decline and dementia remains a priority of the NIA. As part of this
work, there is growing recognition that social participation and community connectedness may reduce the risk
of these diseases. Unfortunately, this research has provided little specificity into how various social activities
may differentially predict cognitive decline. There has also been little inquiry into how older adult social
participation or its relationship with cognition might differ by gender.
Unlike many standard survey items (e.g., health, education), there is insufficient consistency with how social
participation is measured in social surveys and utilized in empirical research. In particular, the use of social
participation “summary measures” (a) may obscure differential associations between cognition and underlying
social activities, and (b) often include items that are, arguably, not “social participation” (e.g., meeting with
family members). This has resulted in two limitations: One, it is not known which social activities—and to what
extent these activities—are driving any associations. Two, it is difficult to compare results among similar
studies, raising concerns about validity and reliability.
This project has three aims. One, we will investigate how associations between social participation and older
adult cognitive functioning differ by social activity. Two, we will identify mechanisms that link particular social
activities to cognitive health. Three, we will investigate to what extent associations between social participation
and older adult cognitive functioning differ by gender. To accomplish these goals, we will utilize four large
nationally representative longitudinal studies of older adults.
Dr. Eric Vogelsang, PI, has an established publication record of older adult social participation and health
research. The collaborators on this project have extensive experience in cognitive functioning research,
mentoring, and NIH grants. Working at a “Super” Hispanic Serving Institution (CSU-San Bernardino), the
project will provide research experience to students with limited opportunities.
The proposed study will produce three benefits. One, it will inform patients, practitioners, and policy makers
looking to delay or prevent the onset of cognitive decline. Two, it will bring recognition to the health implications
of gender inequality in older adult social activity. Three, we expect this work to motivate standardization of
“social participation” measures in social surveys.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
国内基金
海外基金
登录
查看更多内容
补阳还五汤通过AGE-RAGE通路调控脓毒症免疫失衡的机制与转化研究
-
批准号:JCZRLH202601523
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2026
-
负责人:
-
依托单位:
靶向递送一氧化碳调控AGE-RAGE级联反应促进糖尿病创面愈合研究
-
批准号:JCZRQN202500010
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2025
-
负责人:
-
依托单位:
对香豆酸抑制AGE-RAGE-Ang-1通路改善海马血管生成障碍发挥抗阿尔兹海默病作用
-
批准号:2025JJ70209
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2025
-
负责人:雷芬芳
-
依托单位:
AGE-RAGE通路调控慢性胰腺炎纤维化进程的作用及分子机制
-
批准号:--
-
项目类别:面上项目
-
资助金额:--
-
批准年份:2024
-
负责人:万荣
-
依托单位:
甜茶抑制AGE-RAGE通路增强突触可塑性改善小鼠抑郁样行为
-
批准号:2023JJ50274
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2023
-
负责人:贺志明
-
依托单位:
蒙药额尔敦-乌日勒基础方调控AGE-RAGE信号通路改善术后认知功能障碍研究
-
批准号:--
-
项目类别:地区科学基金项目
-
资助金额:33万元
-
批准年份:2022
-
负责人:都义日
-
依托单位:
补肾健脾祛瘀方调控AGE/RAGE信号通路在再生障碍性贫血骨髓间充质干细胞功能受损的作用与机制研究
-
批准号:--
-
项目类别:面上项目
-
资助金额:52万元
-
批准年份:2022
-
负责人:叶宝东
-
依托单位:
LncRNA GAS5在2型糖尿病动脉粥样硬化中对AGE-RAGE 信号通路上相关基因的调控作用及机制研究
-
批准号:
-
项目类别:省市级项目
-
资助金额:10.0万元
-
批准年份:2022
-
负责人:于海兵
-
依托单位:
围绕GLP1-Arginine-AGE/RAGE轴构建探针组学方法探索大柴胡汤异病同治的效应机制
-
批准号:81973577
-
项目类别:面上项目
-
资助金额:55.0万元
-
批准年份:2019
-
负责人:辛贵忠
-
依托单位:
AGE/RAGE通路microRNA编码基因多态性与2型糖尿病并发冠心病的关联研究
-
批准号:81602908
-
项目类别:青年科学基金项目
-
资助金额:18.0万元
-
批准年份:2016
-
负责人:刘括
-
依托单位: