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Center for Label-free Imaging and Multiscale Biophotonics (CLIMB)

无标记成像和多尺度生物光子学中心 (CLIMB)

基本信息

批准号：
10705138
负责人：
Stephen A Boppart
金额：
$ 140.11万
依托单位：
UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-09-30 至 2027-06-20
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10705138
关键词：
Address Adoption Biological Markers Biophotonics Books Chemicals Clinic Clinical Research Clinical Trials Collaborations Communities Contrast Media Cost Sharing Decision Making Education Educational Materials Educational workshop Enrollment Environment Equipment Evaluation Faculty Feedback Fellowship Funding Healthcare Human Image Imaging technology Label Lead Malignant Neoplasms Microscopy Minority Groups Monitor Neurodegenerative Disorders Optical Coherence Tomography Optics Phase Postdoctoral Fellow Procedures Process Productivity Program Development Research Research Personnel Resources Schools Series Specificity Specimen Students Technology Time Training Training Programs Translating Underrepresented Populations Writing clinical application clinical practice commercialization contrast imaging deep learning diversity and inclusion expectation experience imaging modality improved in vivo in vivo imaging innovation member multimodality new technology next generation open source operation optical imaging point of care programs residence service programs synergism technology research and development technology training tool webinar

项目摘要

SUMMARY The Center for Label-free Imaging and Multiscale Biophotonics (CLIMB) develops cutting-edge optical and computational imaging technologies for addressing grand challenges in biomedicine, including cancer and neurodegenerative diseases. Building upon the recent advances in interferometric, nonlinear, chemical, and computational imaging at UIUC, CLIMB will establish a unique technology and training hub for cutting-edge biophotonics. Specifically, the three Technology Research and Development (TRD) projects will synergize expertise in multimodal and nonlinear imaging from the Boppart group, computational imaging from the Anastasio group, and quantitative phase imaging, from the Popescu group, to translate new technology from lab-to-clinic and point-of-care settings. The unifying concept for the technologies developed at CLIMB is the ability to extract quantitative biomarkers from specimens using intrinsic contrast imaging, i.e., label-free. These technologies will be pushed for the first time to handheld configurations to allow in-vivo and point-of-care (POC) operation. We developed a rigorous and inclusive technology training and dissemination plan, as well as a comprehensive educational program to prepare the next generation of biophotonics researchers for excelling in label-free imaging.

总结