Diet and the Adolescent Brain

饮食与青少年大脑

基本信息

  • 批准号:
    10705079
  • 负责人:
  • 金额:
    $ 18.56万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2022
  • 资助国家:
    美国
  • 起止时间:
    2022-09-15 至 2024-08-31
  • 项目状态:
    已结题

项目摘要

PROJECT SUMMARY The quality of children’s diet has deteriorated tremendously over the last decades in the U.S. and other developed countries, with increased intake of unhealthy foods and decreased consumption of healthy foods. The effects of children’s diet on obesity and chronic disease have been well-studied, but recent evidence suggests that children’s diet also affects their behavioral, emotional, and academic functioning. However, little is known about the neural substrates that may underlie these effects. Studies with animal models convincingly demonstrate that ‘Western’ diet – high in saturated fat and added sugars – has a profound negative effects on cognition and behavior through impairments in frontal, limbic, and hippocampal areas of the brain. However, few studies have examined connections between diet and the brain in humans. The relationships between diet, behavior, and academic outcomes are particularly relevant in early adolescence when diet quality typically deteriorates; behavioral, emotional, and academic problems increase; and the brain undergoes rapid development and reorganization that make it more vulnerable to environmental influences. Because virtually nothing is known about the impact of diet on the adolescent brain, this R21 application aims to examine associations between adolescents’ diet and white matter microstructure, neurochemistry, and brain function on tasks related to 1) sustained attention, 2) learning and memory, and 3) emotional and behavioral regulation. We leverage longitudinal, multi-source data collected through the ongoing Adolescent Diet Study, which conducts a full week of daily 24-hour diet recalls and lunch observations on 288 middle school students annually in 6th, 7th, and 8th grade. This R21 project would add a single neuroimaging session, IQ screen, and nutrition biomarkers for a random subset of 80 participants after the 8th grade assessment. Integrated data from both studies will allow us to determine the relationships of intake of saturated fats and added sugars with key aspects of the adolescent brain that underlie behavioral, emotional, and academic functioning – white matter microstructure, neurochemistry, and brain function on tasks of attention, verbal memory, and emotional and behavioral regulation. Better understanding of the connections between diet and the adolescent brain will facilitate more effective public health messaging and nutrition-focused interventions to enhance healthy brain development and improve emotional, behavioral, and academic outcomes of youth.
项目总结

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ monograph.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ sciAawards.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ conferencePapers.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ patent.updateTime }}

DAVID C KNIGHT其他文献

DAVID C KNIGHT的其他文献

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

{{ truncateString('DAVID C KNIGHT', 18)}}的其他基金

Diet and the Adolescent Brain
饮食与青少年大脑
  • 批准号:
    10429601
  • 财政年份:
    2022
  • 资助金额:
    $ 18.56万
  • 项目类别:
Neurobiological Mechanisms of Lower Internalizing Disorders in Black Americans
美国黑人较低内化障碍的神经生物学机制
  • 批准号:
    8507492
  • 财政年份:
    2012
  • 资助金额:
    $ 18.56万
  • 项目类别:
Neurobiological Mechanisms of Lower Internalizing Disorders in Black Americans
美国黑人较低内化障碍的神经生物学机制
  • 批准号:
    9070767
  • 财政年份:
    2012
  • 资助金额:
    $ 18.56万
  • 项目类别:
Neurobiological Mechanisms of Lower Internalizing Disorders in Black Americans
美国黑人较低内化障碍的神经生物学机制
  • 批准号:
    8386845
  • 财政年份:
    2012
  • 资助金额:
    $ 18.56万
  • 项目类别:
Neurobiological Mechanisms of Lower Internalizing Disorders in Black Americans
美国黑人较低内化障碍的神经生物学机制
  • 批准号:
    8687745
  • 财政年份:
    2012
  • 资助金额:
    $ 18.56万
  • 项目类别:
Neurobiological Mechanisms of Lower Internalizing Disorders in Black Americans
美国黑人较低内化障碍的神经生物学机制
  • 批准号:
    8687774
  • 财政年份:
    2012
  • 资助金额:
    $ 18.56万
  • 项目类别:
Neurobiological Mechanisms of Lower Internalizing Disorders in Black Americans
美国黑人较低内化障碍的神经生物学机制
  • 批准号:
    8917393
  • 财政年份:
    2012
  • 资助金额:
    $ 18.56万
  • 项目类别:
FUNCTIONAL NEUROANATOMY OF FEAR CONDITIONING
恐惧调节的功能神经解剖学
  • 批准号:
    6139345
  • 财政年份:
    2000
  • 资助金额:
    $ 18.56万
  • 项目类别:
FUNCTIONAL NEUROANATOMY OF FEAR CONDITIONING
恐惧调节的功能神经解剖学
  • 批准号:
    2857991
  • 财政年份:
    1999
  • 资助金额:
    $ 18.56万
  • 项目类别:
FUNCTIONAL NEUROANATOMY OF FEAR CONDITIONING
恐惧调节的功能神经解剖学
  • 批准号:
    2516598
  • 财政年份:
    1998
  • 资助金额:
    $ 18.56万
  • 项目类别:

相似海外基金

Pharmacy-led Transitions of Care Intervention to Address System-Level Barriers and Improve Medication Adherence in Socioeconomically Disadvantaged Populations
药房主导的护理干预转型,以解决系统层面的障碍并提高社会经济弱势群体的药物依从性
  • 批准号:
    10594350
  • 财政年份:
    2023
  • 资助金额:
    $ 18.56万
  • 项目类别:
Evaluating Centralizing Interventions to Address Low Adherence to Lung Cancer Screening Follow-up in Decentralized Settings
评估集中干预措施,以解决分散环境中肺癌筛查随访依从性低的问题
  • 批准号:
    10738120
  • 财政年份:
    2023
  • 资助金额:
    $ 18.56万
  • 项目类别:
Suubi-Mhealth: A mobile health intervention to address depression and improve ART adherence among Youth living with HIV (YLHIV) in Uganda
Suubi-Mhealth:一种移动健康干预措施,旨在解决乌干达艾滋病毒感染者 (YLHIV) 青少年的抑郁症问题并提高抗逆转录病毒疗法的依从性
  • 批准号:
    10526768
  • 财政年份:
    2022
  • 资助金额:
    $ 18.56万
  • 项目类别:
Suubi-Mhealth: A mobile health intervention to address depression and improve ART adherence among Youth living with HIV (YLHIV) in Uganda
Suubi-Mhealth:一种移动健康干预措施,旨在解决乌干达艾滋病毒感染者 (YLHIV) 青少年的抑郁症问题并提高抗逆转录病毒疗法的依从性
  • 批准号:
    10701072
  • 财政年份:
    2022
  • 资助金额:
    $ 18.56万
  • 项目类别:
A behavioral intervention for Black men who have sex with men and live with HIV to address intersectional stigma and improve antiretroviral therapy adherence
针对男男性行为且感染艾滋病毒的黑人男性进行行为干预,以解决交叉耻辱并提高抗逆转录病毒治疗的依从性
  • 批准号:
    10679092
  • 财政年份:
    2021
  • 资助金额:
    $ 18.56万
  • 项目类别:
A behavioral intervention for Black men who have sex with men and live with HIV to address intersectional stigma and improve antiretroviral therapy adherence
针对男男性行为且感染艾滋病毒的黑人男性进行行为干预,以解决交叉耻辱并提高抗逆转录病毒治疗的依从性
  • 批准号:
    10432133
  • 财政年份:
    2021
  • 资助金额:
    $ 18.56万
  • 项目类别:
A behavioral intervention for Black men who have sex with men and live with HIV to address intersectional stigma and improve antiretroviral therapy adherence
针对男男性行为且感染艾滋病毒的黑人男性进行行为干预,以解决交叉耻辱并提高抗逆转录病毒治疗的依从性
  • 批准号:
    10327065
  • 财政年份:
    2021
  • 资助金额:
    $ 18.56万
  • 项目类别:
Leveraging Technology to Address Access and Adherence to Conventional Hospital-Based Pulmonary Rehabilitation in Veterans with COPD
利用技术解决慢性阻塞性肺病退伍军人接受和坚持传统医院肺康复的问题
  • 批准号:
    10377366
  • 财政年份:
    2019
  • 资助金额:
    $ 18.56万
  • 项目类别:
Leveraging Technology to Address Access and Adherence to Conventional Hospital-Based Pulmonary Rehabilitation in Veterans with COPD
利用技术解决慢性阻塞性肺病退伍军人接受和坚持传统医院肺康复的问题
  • 批准号:
    10574496
  • 财政年份:
    2019
  • 资助金额:
    $ 18.56万
  • 项目类别:
Targeted interventions to address the multi-level effects of gender-based violence on PrEP uptake and adherence among adolescent girls and young women in Kenya
有针对性的干预措施,以解决性别暴力对肯尼亚少女和年轻妇女接受和坚持 PrEP 的多层面影响
  • 批准号:
    9403567
  • 财政年份:
    2017
  • 资助金额:
    $ 18.56万
  • 项目类别:
{{ showInfoDetail.title }}

作者:{{ showInfoDetail.author }}

知道了