Effect of music intervention on infants' brainstem encoding of speech
音乐干预对婴儿脑干言语编码的影响
基本信息
- 批准号:10016848
- 负责人:
- 金额:$ 23.33万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2019
- 资助国家:美国
- 起止时间:2019-09-15 至 2022-08-31
- 项目状态:已结题
- 来源:
- 关键词:AddressAdultAffectAge-MonthsAreaAuditoryBasic ScienceBehaviorBehavioralBrain StemCaregiversChildClinicalCommunication impairmentDevelopmentDevelopmental Communication DisordersEmotionalExhibitsFrequenciesFutureGoalsGuidelinesInfantInterventionKnowledgeLaboratoriesLaboratory StudyLanguageLanguage DevelopmentLanguage DisordersLearningLifeMeasurementMeasuresMethodsMovementMusicPathway interactionsPlayProcessProtocols documentationResearchResearch PersonnelRiskSensorySpeechSpeech DevelopmentSpeech DisordersSpeech SoundSystemTestingTimeTrainingWorkcognitive skillexperiencefundamental researchimprovedindividual variationinfancyintervention programlexicalnon-Nativerelating to nervous systemresponseskillssocial
项目摘要
Project Summary/Abstract
Music learning that starts early in development has profound and long-lasting benefits later in life, within
and beyond the music domain, in important areas such as speech and language skills, cognitive skills
and social/emotional skills. Previously, work by the PI demonstrated that a short-term music
intervention at as early as 9 months of age, during the ‘sensitive period’ for speech learning, can
already affect cortical processing beyond music. That is, infant who underwent the music intervention
also exhibited enhanced cortical processing of nonnative speech compared to the controls who
underwent free play sessions. The proposed project aims to expand on these results and investigate
the extent of the effects from the music intervention in infancy, more specifically, whether the music
intervention can already modulate speech encoding at the lower level auditory brainstem.
Understanding this question is critical from a theoretical and an application perspective. Theoretically,
the results will improve the basic scientific understanding of mechanisms underlying the effects related
to music intervention and its interaction with early development and speech learning. In practice, the
knowledge we gain from the basic research will help future implementation of early music intervention
programs as an alternative method to improve early speech and later language learning, for typically
developing infants and more importantly, for infants at-risk for speech and language disorders. The first
study (Aim 1) will measure infants’ brainstem encoding of nonnative lexical tones at 7 months and 11
months of age. The results from this group will serve as controls for Aim 2. At the same time, the results
from Aim 1 will also establish the typical developmental trajectory for brainstem encoding of lexical
tones, which has not been established before. The results will thus also expand our current
understanding of behavioral and neural changes that take place during the ‘sensitive period’ for
phonetic learning. In the second study (Aim 2), infants will complete the previously-established music
intervention starting at 9 months of age, in addition to the brainstem measurements at 7 and 11 months
of age. Their results will be compared to the controls (Aim 1) to address the effects related to the music
intervention. Together, the proposed study will further our understanding of the effect related to music
intervention in infancy and its underlying mechanisms. This project will also help the PI to take a big
step towards her long-term goal to apply early music intervention to help infants at-risk for
communication disorders.
项目总结/摘要
音乐学习,在发展的早期开始有深远的和持久的利益,在以后的生活中,
在音乐领域之外,在演讲和语言技能,认知技能等重要领域,
和社交/情感技能。此前,PI的工作表明,短期音乐
早在9个月大的时候,在语言学习的“敏感期”进行干预,
已经影响到了音乐之外的大脑皮层处理也就是说,接受音乐干预的婴儿
与对照组相比,
进行自由活动。拟议的项目旨在扩大这些结果,并调查
婴儿期音乐干预的影响程度,更具体地说,
干预已经可以调节较低水平听觉脑干的语音编码。
从理论和应用的角度来看,理解这个问题至关重要。从理论上讲,
这些结果将提高对相关影响的机制的基本科学认识,
音乐干预及其与早期发展和言语学习的相互作用。在实践上许多
我们从基础研究中获得的知识将有助于未来早期音乐干预的实施
程序作为一种替代方法,以改善早期的讲话和后来的语言学习,为典型的
发育中的婴儿,更重要的是,对于有言语和语言障碍风险的婴儿。第一
研究(目标1)将测量7个月和11个月婴儿对非母语词汇音调的脑干编码
月龄。该组的结果将作为目标2的对照。与此同时,
目的1的研究也将建立词汇的脑干编码的典型发展轨迹
这是以前没有建立过的。结果也将扩大我们目前的
了解在“敏感期”发生的行为和神经变化,
语音学习在第二项研究中(目标2),婴儿将完成先前建立的音乐
除了在7个月和11个月时进行脑干测量外,还从9个月大时开始进行干预
年龄。他们的结果将与对照组(目标1)进行比较,以解决与音乐相关的影响
干预总之,拟议的研究将进一步加深我们对音乐相关效应的理解
婴儿期的干预及其潜在机制。这个项目也将帮助PI采取一个大的
迈向她长远目标,即应用早期音乐介入,帮助有患上自闭症风险的婴儿,
沟通障碍
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Tian Zhao其他文献
Tian Zhao的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Tian Zhao', 18)}}的其他基金
Early predictors of Late Talking (LT) in infancy
婴儿期晚说话 (LT) 的早期预测因素
- 批准号:
10839687 - 财政年份:2022
- 资助金额:
$ 23.33万 - 项目类别:
Neural mechanisms underlying the sensitive period for phonetic learning in infants at-risk for Developmental Language Disorder
发育性语言障碍婴儿语音学习敏感期的神经机制
- 批准号:
10647811 - 财政年份:2022
- 资助金额:
$ 23.33万 - 项目类别:
相似海外基金
Co-designing a lifestyle, stop-vaping intervention for ex-smoking, adult vapers (CLOVER study)
为戒烟的成年电子烟使用者共同设计生活方式、戒烟干预措施(CLOVER 研究)
- 批准号:
MR/Z503605/1 - 财政年份:2024
- 资助金额:
$ 23.33万 - 项目类别:
Research Grant
Early Life Antecedents Predicting Adult Daily Affective Reactivity to Stress
早期生活经历预测成人对压力的日常情感反应
- 批准号:
2336167 - 财政年份:2024
- 资助金额:
$ 23.33万 - 项目类别:
Standard Grant
RAPID: Affective Mechanisms of Adjustment in Diverse Emerging Adult Student Communities Before, During, and Beyond the COVID-19 Pandemic
RAPID:COVID-19 大流行之前、期间和之后不同新兴成人学生社区的情感调整机制
- 批准号:
2402691 - 财政年份:2024
- 资助金额:
$ 23.33万 - 项目类别:
Standard Grant
Migrant Youth and the Sociolegal Construction of Child and Adult Categories
流动青年与儿童和成人类别的社会法律建构
- 批准号:
2341428 - 财政年份:2024
- 资助金额:
$ 23.33万 - 项目类别:
Standard Grant
Elucidation of Adult Newt Cells Regulating the ZRS enhancer during Limb Regeneration
阐明成体蝾螈细胞在肢体再生过程中调节 ZRS 增强子
- 批准号:
24K12150 - 财政年份:2024
- 资助金额:
$ 23.33万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Understanding how platelets mediate new neuron formation in the adult brain
了解血小板如何介导成人大脑中新神经元的形成
- 批准号:
DE240100561 - 财政年份:2024
- 资助金额:
$ 23.33万 - 项目类别:
Discovery Early Career Researcher Award
RUI: Evaluation of Neurotrophic-Like properties of Spaetzle-Toll Signaling in the Developing and Adult Cricket CNS
RUI:评估发育中和成年蟋蟀中枢神经系统中 Spaetzle-Toll 信号传导的神经营养样特性
- 批准号:
2230829 - 财政年份:2023
- 资助金额:
$ 23.33万 - 项目类别:
Standard Grant
Usefulness of a question prompt sheet for onco-fertility in adolescent and young adult patients under 25 years old.
问题提示表对于 25 岁以下青少年和年轻成年患者的肿瘤生育力的有用性。
- 批准号:
23K09542 - 财政年份:2023
- 资助金额:
$ 23.33万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Identification of new specific molecules associated with right ventricular dysfunction in adult patients with congenital heart disease
鉴定与成年先天性心脏病患者右心室功能障碍相关的新特异性分子
- 批准号:
23K07552 - 财政年份:2023
- 资助金额:
$ 23.33万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Issue identifications and model developments in transitional care for patients with adult congenital heart disease.
成人先天性心脏病患者过渡护理的问题识别和模型开发。
- 批准号:
23K07559 - 财政年份:2023
- 资助金额:
$ 23.33万 - 项目类别:
Grant-in-Aid for Scientific Research (C)