Improving Health Research Skills for AI/AN Students and Fellows

项目概要： 传染病和慢性病的发病率和死亡率有明显的差别， 美国印第安人和阿拉斯加原住民（AI/AN）部落与美国白人相比， 健康指标显示，印第安人/土著民族的健康状况相对较差。虽然数量可观， 研究旨在了解高发病率和健康差异的原因 在AI/AN人群中，AI/AN研究人员参与的大多数研究都特别 不常见。由于文化因素是许多临床设计和实施的核心， 行为，或基于人口的研究，增加AI/AN人民的参与，以进行有效的 AI/AN人群的研究应该是优先关注的问题。本申请中描述的程序将 提高人工智能/人工智能调查人员的研究能力，以便在内部进行精心设计的调查 AI/AN人群和其他环境中。经验丰富的流行病学家、生物统计学家、伦理学家和其他 西北波特兰地区印第安人健康委员会（委员会），俄勒冈州健康与科学研究人员 大学和波特兰州立大学将为合格的AI/AN提供个性化的培训计划 不同层次的研究人员，包括研究生，卫生专业的学生，和董事会 员工培训计划将向参与者介绍各种研究策略，测量 问题，研究设计考虑，数据管理，数据分析，准备赠款申请， 研究伦理和手稿准备。量身定制的研讨会和指导， 研究人员和同行导师将成为培训经验的重要组成部分。我们将建立明确的 每个受训人员的基准，包括完成研究生学位，我们将 支持.这项建议建立在现有的赠款资助的培训计划，为人工智能/安学员在我们的 学术合作伙伴机构，并将通过能力促进AI/AN研究人员的职业发展 建筑和研究技能发展。通过开发合格的独立AI/AN 调查人员，我们的努力可能最终有助于减少健康方面的许多差异， 在AI/AN群体中观察到，与全国范围内的美国白人相比， research.

PROJECT SUMMARY: Marked differences in infectious and chronic disease incidence and mortality rates have been documented among American Indian and Alaska Native (AI/AN) tribes nationwide compared to U.S. whites, and most health indicators show that AI/AN people have comparatively poor health status. Although substantial research has been directed toward understanding reasons for high disease rates and health disparities among AI/AN people, involvement by AI/AN researchers in most of these studies has been particularly infrequent. Because cultural factors are central to the design and implementation in many clinical, behavioral, or population-based studies, increasing the involvement of AI/AN peoples to carry out effective research in AI/AN populations should be a priority concern. The program described in this application will increase the research capabilities of AI/AN investigators to carry out well-designed investigations within AI/AN populations and in other settings. Experienced epidemiologists, biostatisticians, ethicists, and other researchers at the Northwest Portland Area Indian Health Board (the Board), Oregon Health & Science University, and Portland State University will offer an individually-tailored training program for qualified AI/AN researchers at different levels—including graduate students, health professions students, and Board employees. The training program will introduce participants to various research strategies, measurement issues, study design considerations, data management, data analysis, preparation of grant applications, ethics of research, and manuscript preparation. Tailored seminars and mentoring from seasoned researchers and peer mentors will form a key part of the training experience. We will establish clear benchmarks for each trainee, including completion of a graduate degree for the fellows whom we will support. This proposal builds upon existing grant-funded training programs for AI/AN trainees at our academic partner institutions, and will further the career development of AI/AN researchers through capacity building and research skill development. Through the development of qualified, independent AI/AN investigators, our effort may ultimately serve to reduce some of the many disparities in health that are observed among AI/AN groups, compared to U.S. whites nationwide, as well as reduce tribes’ distrust of research.