Neuropathogenesis of varicella zoster virus infection

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Varicella zoster virus (VZV) is a herpesvirus which causes chicken pox and shingles. Shingles affects many elderly people and a major complication is prolonged severe pain or post-herpetic neuralgia, often needing follow-up medical care for months to years. Despite its impact on the community, little is known about how this virus functions and causes disease. We aim to improve our understanding of how VZV infects nerve cells to provide new information for the development of new treatments.