Career Enhancement Core

职业提升核心

• 批准号: 10001435
• 负责人: MICHAEL J MUGAVERO
• 金额: $ 6.41万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-01 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10001435
• 关键词: Academy; Active Learning; Center for Translational Science Activities; Clinical Competence; Clinical Research; Clinical Sciences; Clinical Trials; Collaborations; Communicable Diseases; Communication; Communities; Competence; Complement; Congenital herpes simplex; Contracts; Critiques; Development; Disease; Educational Activities; Eligibility Determination; Ensure; Enterovirus; Ethics; Faculty; Fostering; Foundations; Funding; Goals; Grant; Growth; Individual; Industry; Information Dissemination; Institution; Investigation; Journals; Knowledge; Leadership; Medicine; Mentors; Methodology; Neonatal; Parechovirus; Patients; Pediatric cohort; Peer Review; Perinatal Infection; Publications; Publishing; Rare Diseases; Research; Research Activity; Research Design; Research Methodology; Research Personnel; Research Project Grants; Research Training; Science; Sepsis; Simplexvirus; Training; Training Programs; Translational Research; Virus Diseases; Writing; base; career; career development; clinical center; cohort; congenital cytomegalovirus; congenital infection; experience; externship; innovation; meetings; next generation; pharmacometrics; professor; programs; recruit; research and development; sabbatical; skills; success; training opportunity; translational scientist

The Congenital and Perinatal Infections Consortium (CPIC) Career Enhancement Core will impact the research career development of the next generation of rare diseases researchers focusing on congenital cytomegalovirus (CMV) disease, neonatal herpes simplex virus (HSV) infection, and neonatal enterovirus (EV) and parechovirus (HPeV) sepsis. The Career Enhancement Core will promote the development of research skills and knowledge for those at all career stages in support of a diverse, innovative, and ethically rigorous research base. The overall goal of the Core is to provide didactic and experiential training in clinical and translational research in order to enhance scientific knowledge and an understanding of stakeholder perspectives unique to the rare diseases patient cohort. To develop CPIC Research Scholars, the Career Enhancement Core will: 1) identify and recruit a promising and diverse cohort of pediatric investigators for career enhancement and mentored research in rare diseases caused by congenital and perinatal infections; 2) expand the formal training of nascent investigators in research methodology, rigorous study design and scientific writing, all skills that are crucial to successful investigation and dissemination of findings in collaboration with UAB's NCATS-funded Center for Clinical and Translational Science (CCTS); and 3) stimulate experiential learning via the development of externships or “mini-sabbaticals” within the CPIC, including industry and community stakeholder partners. Externships across the CPIC will expand and foster increased collaborations and interactions between consortium institutions in a way that contributes to outstanding science and further growth of our research base. Led by Michael J. Mugavero, MD, MHSc, the Career Enhancement Oversight Committee will select fellows and early stage investigators as Research Scholars. These Scholars will receive training in a variety of skills including: 1) the regulatory and ethical requirements of research; special topics specific to rare diseases and CPIC-specific research such as pharmacometrics, 2) an understanding of stakeholder perspective and the communication of scientific results in appropriate formats for different audiences, and methodological issues related to study design and implementation; 3) core competencies of clinical and translational science, including clinical trials considerations as well as grant writing and dissemination of results; and 4) skills needed to review and critique published rare diseases research. In addition to this foundational training, Research Scholars will also receive experiential, mentored research training by Program Faculty.

先天性和围产期感染联盟(CPIC)职业提升核心将影响 关注先天性的下一代罕见病研究人员的研究生涯发展 巨细胞病毒病、新生儿单纯疱疹病毒感染和新生儿肠道病毒 和猪细小病毒(HPeV)败血症。职业提升核心将推动研究的发展 为所有职业阶段的人提供技能和知识，以支持多样化、创新性和道德严谨的 研究基地。核心的总体目标是提供教学和体验式培训在临床和 翻译研究，以提高科学知识和对利益相关者的理解 罕见疾病患者队列所特有的观点。 为了培养CPIC研究学者，职业提升核心将：1)寻找和招聘有前途的 以及不同的儿科研究人员队伍，以促进职业发展和指导罕见疾病的研究 由先天和围产期感染引起；2)扩大对新入职调查人员的正规培训 研究方法、严谨的研究设计和科学的写作，所有这些技能都是成功的关键 与UAB的NCATS资助的临床和治疗中心合作调查和传播研究结果 翻译科学(CCTS)；以及3)通过发展外部学习或 CPIC内部的“小长假”，包括行业和社区利益相关者合作伙伴。外轮横跨 CPIC将扩大和促进财团机构之间在 为杰出的科学和我们的研究基础的进一步发展做出贡献的方式。 由迈克尔·J·穆加维罗领导，医学博士，理工学院硕士，职业提升监督委员会将挑选研究员 和早期研究人员作为研究学者。这些学者将接受各种技能的培训 包括：1)研究的监管和道德要求；针对罕见疾病和 CPIC特定研究，如药物计量学，2)理解利益相关者的视角和 以适当的形式向不同受众传播科学成果，以及方法问题 与研究设计和实施有关；3)临床和转化科学的核心能力， 包括临床试验的考虑以及拨款的编写和结果的传播；以及4)所需的技能 回顾和评论已发表的罕见病研究。除了这一基础培训，研究 学者还将接受由项目学院提供的体验式、指导性研究培训。