Northwest Genomics Center for All of Us
Northwest Genomics Center for All of Us
批准号:
10003446
负责人:
Evan Eichler
金额:
$608.87万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2018
资助国家:
美国
项目状态:
已结题
起止时间:
2018-09-25 至 2023-08-31
关键词:
All of Us Research ProgramBioinformaticsCLIA certifiedClinicalDNADataData AnalysesEnrollmentEnvironmentGenesGenomeGenomicsGenotypeGoalsHuman GenomeIndividualInfrastructureInternationalLaboratoriesLogisticsManagement Information SystemsMetadataMethodsPatientsPersonnel StaffingProcessPublicationsQuality ControlReportingResearchResearch PersonnelSamplingSecureTrainingTranslational ResearchUnited States National Institutes of HealthVariantWorkbiobankempoweredexperienceflexibilitygenome sequencinginstrumentationprogramswhole genome
中文摘要
西北我们所有人基因组中心(NWGC)的目标是提供高通量的基因分型和
我们所有人研究计划中登记的个人的全基因组测序(WGS)使用高度
成功的管道已经对近20万个样本和数万个
数以千计的高质量人类基因组。西北基因组学中心汇集了国际上三个
公认的PI(Nickerson(Contact)、Eichler和Jarvik),在高通量临床方面拥有数十年的专业知识
基因组学和他们的合作调查人员已经将数万种不同的解释返回到
病人。正如我们过去对其他NIH项目所做的那样,我们将与我们所有人协调努力
国家高级翻译科学中心(NCATS)的项目团队,其他中心在
计划,如数据和研究中心(DRC)和生物库,以及其他基因组中心(如果选择)。
英文摘要
The goal of the Northwest Genomics Center for All of Us (NWGC) is to provide high-throughput genotyping and
whole genome sequencing (WGS) for individuals enrolled in the All of Us Research Program using a highly
successful pipeline that has produced genotyping on nearly two hundred thousand samples and tens of
thousands of high quality human genomes. The Northwest Genomics Center brings together three internationally
recognized PIs (Nickerson (Contact), Eichler, and Jarvik), with decades of expertise in high-throughput clinical
genomics and, together with their Co-Investigators, have returned tens of thousands of variant interpretations to
patients. As we have done in the past with other NIH programs, we will coordinate our efforts with the All of Us
program team in the National Center for Advancing Translational Sciences (NCATS), the other centers in the
program such as the Data and Research Center (DRC) and the Biobank, and other Genome Centers if selected.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Diversity Action Plan: UW GenOM Project
-
批准号:10189329
-
项目类别:
-
资助金额:$9.3万
-
财政年份:2020
-
负责人:Evan Eichler
-
依托单位:
Center for Human Reference Genome Diversity
-
批准号:10686965
-
项目类别:
-
资助金额:$398.92万
-
财政年份:2019
-
负责人:Evan Eichler
-
依托单位:
Center for Human Reference Genome Diversity
-
批准号:9905992
-
项目类别:
-
资助金额:$335.06万
-
财政年份:2019
-
负责人:Evan Eichler
-
依托单位:
Center for Human Reference Genome Diversity
-
批准号:10020424
-
项目类别:
-
资助金额:$341.44万
-
财政年份:2019
-
负责人:Evan Eichler
-
依托单位:
Center for Human Reference Genome Diversity
-
批准号:10269943
-
项目类别:
-
资助金额:$340.71万
-
财政年份:2019
-
负责人:Evan Eichler
-
依托单位:
Center for Human Reference Genome Diversity
-
批准号:10488272
-
项目类别:
-
资助金额:$340.1万
-
财政年份:2019
-
负责人:Evan Eichler
-
依托单位:
An "Embedded ELSI" Approach to the Creation of a Novel Human PanGenome Reference: Administrative Supplement to the Center for Human Reference Genome Diversity
-
批准号:10622227
-
项目类别:
-
资助金额:$61.14万
-
财政年份:2019
-
负责人:Evan Eichler
-
依托单位:
ELSI Administrative Supplement - Center for Human Reference Genome Diversity
-
批准号:10423448
-
项目类别:
-
资助金额:$24.62万
-
财政年份:2019
-
负责人:Evan Eichler
-
依托单位:
Sequence-resolved structural variation of human genomes
-
批准号:10202688
-
项目类别:
-
资助金额:$63.0万
-
财政年份:2018
-
负责人:Evan Eichler
-
依托单位:
Northwest Genomics Center for All of Us
-
批准号:10884599
-
项目类别:
-
资助金额:$208.48万
-
财政年份:2018
-
负责人:Evan Eichler
-
依托单位:
Sequence resolution of complex human genome structural variation
-
批准号:10656792
-
项目类别:
-
资助金额:$44.1万
-
财政年份:2018
-
负责人:Evan Eichler
-
依托单位:
Northwest Genomics Center for All of Us
-
批准号:10674646
-
项目类别:
-
资助金额:$1399.17万
-
财政年份:2018
-
负责人:Evan Eichler
-
依托单位:
3 of 7 Epi4K: Gene discovery in 4,000 epilepsy genomes
-
批准号:8855979
-
项目类别:
-
资助金额:$3.02万
-
财政年份:2014
-
负责人:Evan Eichler
-
依托单位:
Identifying and Characterizing the Full Spectrum of Haplotype-resolved Structural Variation in Human Genomes
-
批准号:10190985
-
项目类别:
-
资助金额:$269.6万
-
财政年份:2013
-
负责人:Evan Eichler
-
依托单位:
Diversity Action Plan: UW GenOM Project
-
批准号:9763590
-
项目类别:
-
资助金额:$24.75万
-
财政年份:2013
-
负责人:Evan Eichler
-
依托单位:
Sporadic Mutations and Autism Spectrum Disorders
-
批准号:8892260
-
项目类别:
-
资助金额:$64.79万
-
财政年份:2013
-
负责人:Evan Eichler
-
依托单位:
Rare Mutations and Autism Spectrum Disorders
-
批准号:10321284
-
项目类别:
-
资助金额:$69.96万
-
财政年份:2013
-
负责人:Evan Eichler
-
依托单位:
Identifying and Characterizing the Full Spectrum of Haplotype-resolved Structural Variation in Human Genomes
-
批准号:10415958
-
项目类别:
-
资助金额:$269.6万
-
财政年份:2013
-
负责人:Evan Eichler
-
依托单位:
Rare Mutations and Autism Spectrum Disorders
-
批准号:10530630
-
项目类别:
-
资助金额:$68.19万
-
财政年份:2013
-
负责人:Evan Eichler
-
依托单位:
Sporadic Mutations and Autism Spectrum Disorders
-
批准号:8708215
-
项目类别:
-
资助金额:$64.79万
-
财政年份:2013
-
负责人:Evan Eichler
-
依托单位:
海外基金