Administrative Core

行政核心

• 批准号: 10004497
• 负责人: Jill P Buyon
• 金额: $ 20.06万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-22 至 2022-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10004497
• 关键词: Accountability; Address; Adherence; Advisory Committees; Affect; Area; Autoimmunity; Birth; Blood Tests; Budgets; Cellular biology; Child; Clinical; Collaborations; Communication; Computers; Congenital Heart Block; Consultations; Databases; Disease; Education; Ethical Issues; Evaluation; Faculty; Fathers; Feasibility Studies; Fostering; Goals; Health Personnel; Human Resources; Immunology; Individual; Information Dissemination; Infrastructure; Interdisciplinary Study; Journals; Logistics; Lupus; Medical Students; Medicine; Mission; Molecular Profiling; Mothers; Mucosal Immunity; Neonatal lupus erythematosus; Nephritis; Newsletter; Parents; Participant; Pathogenesis; Pathology; Patients; Phenotype; Pilot Projects; Population; Positioning Attribute; Recurrence; Reporting; Research; Research Personnel; Research Project Grants; Rheumatology; Schedule; Schools; Science; Scientist; Secure; Site; Students; Systemic Lupus Erythematosus; T-Lymphocyte; Technology; Test Result; TimeLine; Translational Research; Wife; Work; base; clinical research site; interest; medical schools; meetings; member; microbiome; pre-clinical; professor; programs; recruit; symposium; synergism; visiting scholar

ABSTRACT The overarching goal of this Administrative Core is to provide a means by which the Translational Center for Molecular Profiling in Preclinical and Established Lupus will function seamlessly, covering many logistic areas. Three Specific Aims are proposed to accomplish this goal: Aim 1: To provide oversight for operational integration of the three Research Projects and two additional Cores (Core 1–Research Technology Core; Core 2–Clinical Core). The Administrative Core will provide governance, infrastructure, budgeting and financial accountability, dissemination of communicative materials, planning meetings and completing administrative tasks for all component Research Projects and Cores. Aim 2: To facilitate meaningful interactions among the Center personnel and the Advisory Committee. Two subaims are proposed: a) to continuously develop new initiatives and strategies to promote the interactions and collaborations among the 3 Research Projects and their interactions with the Cores; b) to facilitate communication between Center personnel and the Advisory Committee. The Advisory Committee is proposed to comprise 4 researchers with expertise relating to the proposed Research Projects, and 2 laypersons who will provide critical input on patients' perspectives with regard to feasibility of recruitment, ethical issues, personal and population meaningfulness of the work proposed, and dissemination of results. The Director and Associate Director will organize twice-yearly Advisory Committee meetings, at which the Project Leads will give presentations to the group to assess project progress, adherence to timelines and milestones, as well as the merit of proposed Pilot/Feasibility Studies. Aim 3: To foster translational, interdisciplinary research on SLE at the NYU School of Medicine. Three Subaims describe our strategies: a) Clinical/Translational Liaison: Drs. Izmirly, Belmont and the Director – by virtue of their attendance at clinical sites providing patients for the Clinical Core – will interact with other Rheumatology faculty, fellows, residents and medical students. Their integral involvement is expected to foster patient interest and education and referral of patients seen by the other health care providers. b) Pilot/Feasibility Project Program: Within the School of Medicine and with support from the CTSI, the Director and Associate Director will publicize the opportunity to apply for Pilot and Feasibility Projects relating to SLE. Both the Director (as Director of the Division of Rheumatology) and Associate Director (as Professor of Medicine and Pathology who teaches courses in immunology and pathogenesis in the School of Medicine and Sackler Graduate School of Biomedical Sciences) are well- positioned to encounter, seek out, and encourage promising applicants for such Projects. c) Enrichment Program: The Director and Associate Director will work with the other Project and Core Leads/Associate Leads to invite visiting scholars to give seminars and interact with members of the Center, and arrange for Center members and their students to attend scientific meetings important for the disease theme of this Center.

抽象的 此行政核心的总体目标是提供一种手段 临床前和已建立的狼疮中的分子分析将无缝发挥作用，涵盖许多逻辑 区域。提出了三个具体目标来实现这一目标：目标1：为监督 这三个研究项目和两个其他核心的操作整合（核心1-研究 技术核心；核心2-临床核心）。行政核心将提供治理，基础设施， 预算和财务问责制，传播材料的传播，计划会议和 完成所有组件研究项目和核心的管理任务。目标2：促进 中心人员和咨询委员会之间有意义的互动。两个subiaim是 提议：a）不断制定新的计划和策略来促进互动和 这三个研究项目及其与核心的互动之间的合作； b）促进 中心人员与咨询委员会之间的沟通。提议咨询委员会 完成4位具有与拟议研究项目有关的专业知识的研究人员，以及2个外行人 关于招募可行性，道德问题，将提供有关患者观点的关键意见 提出的工作的个人和人口有意义，以及结果传播。导演和 副主任将组织两次年度咨询委员会会议，该项目领导将在该会议上进行 向小组的演讲，以评估项目进度，遵守时间表和里程碑以及 提议的试点/可行性研究的优点。目标3：促进翻译，跨学科研究 在纽约大学医学院三个Subiaim描述了我们的策略：a）临床/翻译联络： 博士。 Izmirly，Belmont和董事 - 由于他们在临床场所的出席，为患者提供了 临床核心 - 将与其他风湿病学院，研究员，居民和医学生互动。他们的 预计整体参与将促进患者的兴趣和教育以及对患者的转诊 其他医疗保健提供者。 b）飞行员/可行性项目计划：在医学院内和 CTSI的支持，董事兼副董事将宣传申请飞行员和的机会 与SLE有关的可行性项目。董事（作为风湿病学系主任）和 副主任（作为医学和病理学教授，教授免疫学课程和 医学院和萨克勒生物医学科学研究生院的发病机理是很好的 可以遇到，寻找并鼓励对此类项目的有希望的申请。 c）丰富 计划：董事兼副主任将与另一个项目和核心领导/副主管合作 邀请来访的学者给下水道并与中心成员互动，并安排中心 成员及其学生参加该中心疾病主题重要的科学会议。