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Biostatistics Core

生物统计学核心

基本信息

批准号：
10024416
负责人：
Steven J Skates
金额：
$ 26.2万
依托单位：
DANA-FARBER CANCER INST
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-08-03 至 2025-07-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10024416
关键词：
Address Area Biological Markers Biological Models Biometry Biostatistics Core Cancer Center Clinical Clinical Research Clinical Trials Collaborations Communities Computer software Consult Consultations Correlative Study Dana-Farber Cancer Institute Data Data Analyses Data Collection Data Science Databases Development Ensure Evaluation Experimental Designs General Hospitals Grant Human Resources Laboratories Laboratory Animals Malignant Neoplasms Malignant neoplasm of ovary Massachusetts Methodology Methods Mission Monitor Organoids Outcome Ovarian Pathology Process Quality Control Reporting Research Research Personnel Role Skates Statistical Methods Training Translational Research Work anticancer research base career data management data quality design interest laboratory experiment member mid-career faculty preclinical study programs quality assurance statistics

项目摘要

Project Summary The ovarian SPORE Biostatistics Core will provide the statistical and computational support for all three Ovarian Cancer SPORE Projects. This core will also provide support for the Pathology Core, Organoids, Model Systems, and Biomarkers Core and Developmental Projects. This Core will be jointly based at the Massachusetts General Hospital (MGH) Biostatistics Center and Dana-Farber Cancer the Department of Data Sciences at Dana Farber Cancer Institute (DFCI). The Core Directors, Dr. Nabihah Tayob and Dr. Steven Skates, will bring in statistical expertise required for experimental design, pre-clinical and clinical studies, as well as data collection, management, integration, and quality control. The core has identified five key areas where the members of the core will collaborate with project investigators and core leaders to ensure integrated and comprehensive biostatistical support to the entire Ovarian SPORE. The primary role of the Biostatistics Core is to provide biostatistics expertise for the design, conduct, monitoring, analysis, and reporting of laboratory, animal, translational, clinical studies, including associated correlative studies for SPORE Projects, Developmental Research and Career Enhancement Projects, and other Cores. The Biostatistics Core will also provide input on data collection and assist SPORE investigators in coordinating laboratory results with outcomes from clinical studies or clinical/translational research databases, provide short-term biostatistics consulting to the entire group of SPORE researchers, assist in the evaluation of Developmental Research and Career Enhancement Programs and work with SPORE investigators to develop new statistical methods to address problems arising in ovarian cancer research for which no standard methodologies are available.

项目总结