Core D: Special Populations

项目总结 这项提议的目标是建立一个以阿片类药物为主题的多学科研究中心 还有服药过量。这必然包括弱势和未得到充分服务的人口。为了支持这位将军 为了实现这一目标，拟议的特殊人口核心(SPC)将建立基础设施，以招募和留住弱势群体和 服务不足的个人，建设对弱势群体进行道德研究的能力； 作为关于在个人中进行研究的培训和外联的集中资源 大多数人受到过量和阿片类药物相关危害的影响。最高人民法院近期的主要任务是支持 项目负责人通过包括紧急情况在内的多个场所招募和留住与阿片类药物有关的个人 科室、阿片类药物治疗方案、医院/围产期办公室和刑事司法设施； 引导弱势群体参与的伦理考虑，申请机构审查委员会 批准并召开数据安全监测委员会。最高人民法院的长期目标是建立一个可持续的 用于支持在与弱势和未得到充分服务的人群开展工作时提出的实际挑战的资源 遍布罗德岛州的医院网络和布朗等当地大学和研究机构。这个 SPC将提供一系列服务和专业知识，包括：促进接触患者群体， 提供经过招聘和留住最佳实践培训的研究人员，并谈判各种 招募环境、对人体受试者保护的指导以及对所进行研究的监管监督 在弱势人群中，并扩大研究人员的社区，解决这一关键的公共卫生问题 通过这些专题的外联和培训解决这一问题，包括社区司法所涉人口的严重重叠， 阿片类药物使用障碍和过量。 柯特·贝克维斯博士和蒂莫西·弗拉尼根博士将担任该中心的教职员工领导。他们将提供面积 在与CJ和物质使用人群合作方面的专业知识。科学顾问珍妮特·贝尔德博士将提供 在医院中对物质使用障碍(SUD)患者进行的研究领域的专业知识 急诊科和科学顾问Caron Zlotnick博士将提供领域专业知识 患有自闭症的孕妇。公共卫生硕士Michelle McKenzie，核心经理，将监督日常运营，管理 提供核心资源，并在招募、跟踪和跟踪南部非洲人方面提供该领域的专门知识。女士。 培训协调员马蒂诺将专注于开发专门针对监禁环境的教育论坛。 两名研究助理将为项目负责人提供招聘和留用支助。

PROJECT SUMMARY The goal of this proposal is to establish a multi-disciplinary research Center focused on the theme of opioids and overdose. This will necessarily include vulnerable and underserved populations. To support this general goal, the proposed Special Populations Core (SPC) will build infrastructure to recruit and retain vulnerable and underserved individuals, build capacity in the ethical conduct of research with vulnerable populations, and serve as a centralized resource for training and outreach regarding the conduct of research among individuals most impacted by overdose and opioid-related harms. The near-term, primary mission of the SPC is to support Project Leaders to recruit and retain opioid-involved individuals through multiple venues including emergency departments, opioid treatment programs (OTPs), hospital/perinatal offices and criminal justice (CJ) facilities; navigate the ethical considerations of engaging vulnerable populations, apply for Institutional Review Board approval and convene data safety monitoring boards. The long-term goal of the SPC is to build a sustainable resource to support the practical challenges posed when working with vulnerable and underserved populations across Rhode Island hospital networks and Brown and other local Universities and research institutions. The SPC will provide an array of services and expertise including: facilitating access to patient populations, providing research staff trained in best practices of recruitment and retention and negotiating various recruitment settings, guidance in human subjects protection and regulatory oversight of research conducted among vulnerable populations, and broaden the community of researchers addressing this critical public health issue through outreach and training in these topics, including the critical overlap of CJ involved populations, opioid use disorders and overdose. Dr. Curt Beckwith and Dr. Timothy Flanigan will be the faculty leaders of this Core. They will provide area expertise in working with CJ and substance using populations. Dr. Janette Baird, Scientific Advisor, will provide area expertise in research conducted among individuals with substance use disorders (SUD) in hospital Emergency Departments and Dr. Caron Zlotnick, Scientific Advisor, will provide area expertise in working with pregnant women with SUD. Michelle McKenzie, MPH, Core Manager, will oversee routine operations, manage Core resources, and provide area expertise in recruitment, tracking and follow-up of SUD populations. Ms. Martino, Training Coordinator, will focus on developing educational forum specific to the incarcerated setting. Two Research Assistants will provide recruitment and retention support for Project Leaders.