Core D: Special Populations

核心 D：特殊人群

• 批准号: 10256007
• 负责人: CURT G BECKWITH
• 金额: $ 32.02万
• 依托单位: RHODE ISLAND HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-01 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10256007
• 关键词: Accident and Emergency department; Address; Area; Centers of Research Excellence; Certificate of Confidentiality; Clinical Research; Clinical Trials Data Monitoring Committees; Clinics and Hospitals; Communities; Consultations; Course Content; Criminal Justice; Disadvantaged; Education and Outreach; Ethics; Evidence based treatment; Face; Faculty; Goals; Healthcare Systems; Hospitals; Imprisonment; Individual; Infrastructure; Institution; Institutional Review Boards; Interdisciplinary Study; Jail; Mediation; Medical; Mentors; Mission; Opioid; Overdose; Participant; Perinatal; Perinatal Care; Persons; Pharmaceutical Preparations; Population; Pregnant Women; Preparation; Prisoner; Prisons; Protocols documentation; Public Health; Research; Research Assistant; Research Design; Research Personnel; Resources; Rhode Island; Services; Special Population; Stigmatization; Structure; Study Subject; Substance Use Disorder; System; Training; Training Activity; Translational Research; Underserved Population; Universities; Vulnerable Populations; follow-up; human subject protection; illicit opioid; operation; opioid overdose; opioid treatment program; opioid use disorder; opioid user; overdose prevention; patient population; recruit; research study; substance use; webinar

PROJECT SUMMARY The goal of this proposal is to establish a multi-disciplinary research Center focused on the theme of opioids and overdose. This will necessarily include vulnerable and underserved populations. To support this general goal, the proposed Special Populations Core (SPC) will build infrastructure to recruit and retain vulnerable and underserved individuals, build capacity in the ethical conduct of research with vulnerable populations, and serve as a centralized resource for training and outreach regarding the conduct of research among individuals most impacted by overdose and opioid-related harms. The near-term, primary mission of the SPC is to support Project Leaders to recruit and retain opioid-involved individuals through multiple venues including emergency departments, opioid treatment programs (OTPs), hospital/perinatal offices and criminal justice (CJ) facilities; navigate the ethical considerations of engaging vulnerable populations, apply for Institutional Review Board approval and convene data safety monitoring boards. The long-term goal of the SPC is to build a sustainable resource to support the practical challenges posed when working with vulnerable and underserved populations across Rhode Island hospital networks and Brown and other local Universities and research institutions. The SPC will provide an array of services and expertise including: facilitating access to patient populations, providing research staff trained in best practices of recruitment and retention and negotiating various recruitment settings, guidance in human subjects protection and regulatory oversight of research conducted among vulnerable populations, and broaden the community of researchers addressing this critical public health issue through outreach and training in these topics, including the critical overlap of CJ involved populations, opioid use disorders and overdose. Dr. Curt Beckwith and Dr. Timothy Flanigan will be the faculty leaders of this Core. They will provide area expertise in working with CJ and substance using populations. Dr. Janette Baird, Scientific Advisor, will provide area expertise in research conducted among individuals with substance use disorders (SUD) in hospital Emergency Departments and Dr. Caron Zlotnick, Scientific Advisor, will provide area expertise in working with pregnant women with SUD. Michelle McKenzie, MPH, Core Manager, will oversee routine operations, manage Core resources, and provide area expertise in recruitment, tracking and follow-up of SUD populations. Ms. Martino, Training Coordinator, will focus on developing educational forum specific to the incarcerated setting. Two Research Assistants will provide recruitment and retention support for Project Leaders.

项目摘要 该提案的目标是建立一个多学科研究中心，专注于阿片类药物的主题 还有吸毒过量这必然包括弱势和得不到充分服务的人口。支持这位将军 为了实现这一目标，拟议的特殊群体核心（SPC）将建立基础设施，以招募和留住弱势群体， 服务不足的个人，建立与弱势群体一起进行道德研究的能力， 作为在个人之间开展研究的培训和外联的集中资源 大多数受过量和阿片类药物相关危害的影响。SPC的近期主要使命是支持 项目负责人通过包括紧急情况在内的多个场所招募和留住阿片类药物参与者 部门，阿片类药物治疗方案（OTP），医院/围产期办公室和刑事司法（CJ）设施; 浏览参与弱势群体的伦理考虑，申请机构审查委员会 批准并召集数据安全监测委员会。SPC的长期目标是建立一个可持续的 资源，以支持在与弱势和得不到充分服务的人口合作时面临的实际挑战 在罗得岛医院网络和布朗和其他当地大学和研究机构。的 SPC将提供一系列服务和专业知识，包括：促进接触患者人群， 提供接受过招聘和留用最佳做法培训的研究人员， 招募环境、人类受试者保护指南和所进行研究的监管监督 在弱势群体中，并扩大研究人员的社区，解决这一关键的公共卫生 通过这些主题的推广和培训，包括CJ涉及人群的关键重叠， 阿片类药物使用障碍和过量。 博士Curt Beckwith和Timothy Flanigan博士将担任该核心的教师领导。他们将提供区域 与CJ和物质使用人群合作的专业知识。科学顾问Janette Baird博士将提供 在住院的物质使用障碍（SUD）患者中进行研究的领域专长 急诊科和科学顾问Caron Zlotnick博士将提供与以下方面合作的领域专业知识： 妊娠女性SUD Michelle McKenzie，MPH，核心经理，将监督日常运营，管理 核心资源，并提供征聘、跟踪和跟踪可持续发展特别股人口方面的专门知识。女士 Martino，培训协调员，将专注于开发特定于监禁环境的教育论坛。 2名研究助理将为项目负责人提供征聘和留用支助。