Administrative and Coordination Core

行政及协调核心

• 批准号: 10006150
• 负责人: Bruce T Lamb
• 金额: $ 43.54万
• 依托单位: INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-30 至 2021-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10006150
• 关键词: Accounting; Achievement; Address; Administrative Coordination; Administrator; Alzheimer' s Disease; Alzheimer' s disease model; Animal Model; Area; Benchmarking; Bioinformatics; Communication; Communities; Data; Development; Disease model; Doctor of Philosophy; Ensure; Evaluation; Extramural Activities; Feedback; Fostering; Generations; Goals; Grant; Head; Indiana; Laboratories; Leadership; Measures; Medicine; Mission; Modeling; Monitor; Oral; Peer Review; Phenotype; Preclinical Testing; Progress Reports; Publications; Recommendation; Reporting; Research; Research Personnel; Resources; Schedule; Speed; Staging; Time; TimeLine; United States National Institutes of Health; Universities; Work; cost; data management; data standards; data structure; improved; meetings; member; model development; neuroimaging; next generation; operation; programs; structured data; success; synergism; uptake

PROJECT SUMMARY ADMINISTRATIVE (ADMIN) CORE The Administration (ADMIN) Core of the Indiana University (IU)/Jackson Laboratory (JAX) Alzheimer's Disease Precision Models Center (IU/JAX ADPMC), led by ADMIN Head Dr. Bruce Lamb at IU and with assistance from multiple Principle Investigators (mPIs) Dr. Paul Territo at IU and Drs. Greg Carter and Gareth Howell at JAX, along with the support of two PhD-level Program co-Managers and full-time administrators at both IU and JAX, will oversee all administrative and scientific functions of the Center. The ADMIN Core will execute these duties with oversight from an External Advisory Board (EAB), composed of leading experts in the field, and a Center Steering Committee (CSC), composed of the PIs, research leaders at both IU and JAX, and program officials from the NIH. The EAB will convene biannually and the CSC monthly to review progress and provide input and feedback (oral and written) to ensure that the IU/JAX ADPMC (1) achieves its mission, aims, milestones and metrics; (2) effectively deals with any unanticipated problems or concerns; and (3) adapts to likely experimental and technical advances in the field. There will be weekly ADMIN meetings and monthly Core and Project meetings. These will be focused on issues unique to specific Cores/Project while ensuring maximal synergy between the various components of the IU/JAX ADPMC. Close interaction will be fostered among the Bioinformatics and Data Management Core, the Preclinical Testing Core and the Disease Model Development and Phenotyping Project, thus facilitating the speed of discovery while reducing overall cost. One of the primary goals of the ADMIN Core will be to ensure that discoveries made in one area of the ADPMC will benefit the whole, leading to efficiencies in time and cost. Finally, the ADMIN Core will also promote interactions and meetings of the IU/JAX ADPMC with other ongoing research efforts in the Alzheimer's research community, including the NIA-supported ADCs/ADRCs, the Alzheimer's Disease Neuroimaging Initiative (ADNI), Alzheimer's Disease Accelerating Medicine's Partnership (AD-AMP), and the Alzheimer's Disease Sequencing Project (ADSP). The Specific Aims of the IU/JAX ADPMC ADMIN Core are: 1. Provide effective and efficient management, oversight and evaluation of the IU/JAX ADPMC and interactions with the AD research community. 2. Ensure timely and successful completion of all project and core aims and milestones. 3. Facilitate interactions between and among the Bioinformatics and Data Management Core, the Preclinical Testing Core and the Disease Model Development and Phenotyping Project. !

项目摘要行政（admin）核心 印第安纳大学（IU）/杰克逊实验室（JAX）阿尔茨海默氏症的行政部门（管理）核心 疾病精密模型中心（IU/JAX ADPMC），由IU的Bruce Bruce Lamb博士领导 多个原则调查员（MPIS）的协助在IU和Drs的Paul Terito博士。格雷格·卡特（Greg Carter）和 在Jax的Gareth Howell，以及两个博士学位课程共同经理和全职的支持 IU和JAX的管理人员将监督该中心的所有行政和科学功能。 管理员核心将通过外部咨询委员会（EAB）的监督执行这些职责， 由该领域的主要专家组成，由PIS组成的中心指导委员会（CSC） IU和JAX的研究负责人以及NIH的计划官员。 EAB将召集 一年和CSC每月一次，以审查进度，并提供意见和反馈（口头和书面） 确保IU/JAX ADPMC（1）实现其使命，目标，里程碑和指标； （2）有效 处理任何意外的问题或疑虑； （3）适应可能的实验和技术 该领域的进步。将每周举行管理会议以及每月的核心和项目会议。 这些将重点放在特定核心/项目所特有的问题上，同时确保最大协同作用 在IU/JAX ADPMC的各个组件之间。紧密的互动将在 生物信息学和数据管理核心，临床前测试核心和疾病模型 开发和表型项目，从而促进发现速度，同时降低总体成本。 管理员核心的主要目标之一是确保在 ADPMC将使整体受益，从而导致时间和成本的效率。最后，管理员核心也将 促进IU/JAX ADPMC与其他正在进行的研究工作的互动和会议 阿尔茨海默氏症的研究界，包括NIA支持的ADCS/ADRC，阿尔茨海默氏病 神经影像倡议（ADNI），阿尔茨海默氏病加速医学伙伴关系（AD-AMP）和 阿尔茨海默氏病测序项目（ADSP）。 IU/JAX ADPMC管理员核心的具体目的是： 1。提供IU/JAX ADPMC的有效管理，监督和评估 以及与广告研究界的互动。 2.确保及时完成所有项目以及核心目标和里程碑的完成。 3。促进生物信息学和数据管理核心之间的互动， 临床前测试核心以及疾病模型的开发和表型项目。 呢