Genome Technologies and Bioinformatics
基因组技术和生物信息学
基本信息
- 批准号:10006838
- 负责人:
- 金额:$ 23.38万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2016
- 资助国家:美国
- 起止时间:2016-08-05 至 2023-07-31
- 项目状态:已结题
- 来源:
- 关键词:Applications GrantsArchivesBackBioinformaticsBiomedical ResearchCenters of Research ExcellenceCharacteristicsClostridium difficileCollaborationsCommunicable DiseasesCommunitiesCore FacilityDNA sequencingDataData AnalysesData CollectionDatabasesDevelopmentDocumentationEducationEducational workshopEpigenetic ProcessEquipmentExperimental DesignsFacultyFee-for-Service PlansGene ChipsGene ExpressionGenesGenomeGenomicsGoalsHistonesHuman ResourcesImmunobiologyImmunologyInfrastructureInstitutionLaboratoriesLeadershipLibrariesLinear ModelsManuscriptsMassive Parallel SequencingMeasurementMedicineMethodologyMethylationModificationMultivariate AnalysisOligonucleotide MicroarraysPersonsPhaseProcessPseudomonas aeruginosaPublicationsRNAResearchResearch PersonnelReview CommitteeServicesStreamStructureSurveysTechniquesTechnologyTimeLineUniversitiesVariantVermontVocabularybasecollegecostdata acquisitiondata submissiondeep sequencingdesignexomeexome sequencingexperienceexperimental studyfallsgenome sequencinggenome-widegenomic datainstrumentationmembermicrobialpathogenic bacteriaprogramsreference genomesequencing platformstatisticssuccesstranscriptome sequencing
项目摘要
SUMMARY for the Genome Technologies and Bioinformatics Core
The uniformly recognized significance of genomics and bioinformatics for the biomedical research community
is also reflected in needs expressed by VCIID faculty members. This core provides support in all aspects of
genomics, from the design stage, through data acquisition/quality assessment, and finally extensive
bioinformatics support. The core uses an Affymetrix GeneChip and Illumina HiSeq technologies for
oligonucleotide arrays and massively parallel sequencing, respectively. It is currently supporting projects for
11 COBRE faculty members, and has performed genomics data collection and analysis for 86 active COBRE
projects. Preliminary discussions are underway for new projects with 16 additional COBRE faculty members.
Accomplishments from Phases I and II include support for 28 publications, and addition of massively parallel
sequencing services.
Based on over 40 person-years of experience among the Core Directors leading core facilities, they identified
eight essential characteristics needed for the Core: qualified and experienced staff, state-of-the-art equipment,
education, responsiveness, process, experiment design, quality assessment, and sustainability. The Phase III
COBRE objectives of the Genome Technologies and Bioinformatics Core satisfy these essential
characteristics. Specific Aim 1 will provide state-of-the-art equipment, cutting-edge techniques, and
experienced personnel to enhance the research of the VCIID-COBRE. Specific Aim 2 will provide a wide
array of services to VCIID-COBRE faculty to facilitate their research. We will meet this goal by applying our
standard process to projects that includes oversight by a project manager, experiment design, defined
vocabulary, quality assessment, archival storage, and documentation. We have surveyed the user base, and
are prepared to offer efficient and effective service to support VCIID collaborations. Specific Aim 3 will
continue our Phase II plan for sustainability that includes a greatly expanded user base, both at UVM as well
as at several other campuses. We have developed a progressive fee-for-service structure, and are highly
responsive to the need for constant adaptation to changes in research needs. We have received strong
commitments for sustained support from the institution for at least five years beyond Phase III, and we will add
revenue streams based on VCIID collaborations that will sustain our core beyond Phase III.
Our aims and objectives reflect both the eight essential characteristics identified by our leadership and the
VCIID needs identified by a survey of the VCIID. These aims will facilitate the transition of the Core into a fully
self-sustainable facility capable of continuing to support state-of-the-art research.
基因组技术和生物信息学核心概述
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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JEFFREY P. BOND其他文献
JEFFREY P. BOND的其他文献
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{{ truncateString('JEFFREY P. BOND', 18)}}的其他基金
VERMONT IMMUNOBIOL/INFECTIOUS DIS CTR: MICROARRAY & BIOINFORMATIC ANALYSIS CORE
佛蒙特州免疫生物学/传染性盘 CTR:微阵列
- 批准号:
8360769 - 财政年份:2011
- 资助金额:
$ 23.38万 - 项目类别:
VERMONT IMMUNOBIOL/INFECTIOUS DIS CTR: MICROARRAY & BIOINFORMATIC ANALYSIS CORE
佛蒙特州免疫生物学/传染性盘 CTR:微阵列
- 批准号:
8167728 - 财政年份:2010
- 资助金额:
$ 23.38万 - 项目类别:
VERMONT IMMUNOBIOL/INFECTIOUS DIS CTR: MICROARRAY & BIOINFORMATIC ANALYSIS CORE
佛蒙特州免疫生物学/传染性盘 CTR:微阵列
- 批准号:
7959814 - 财政年份:2009
- 资助金额:
$ 23.38万 - 项目类别:
VERMONT IMMUNOBIOL/INFECTIOUS DIS CTR: MICROARRAY & BIOINFORMATIC ANALYSIS CORE
佛蒙特州免疫生物学/传染性盘 CTR:微阵列
- 批准号:
7720913 - 财政年份:2008
- 资助金额:
$ 23.38万 - 项目类别:
CORE--BIOINFORMATICS: BRIN: VERMONT BIOMED RES INFRASTRU
核心--生物信息学:BRIN:佛蒙特州生物医学研究基础设施
- 批准号:
7170629 - 财政年份:2005
- 资助金额:
$ 23.38万 - 项目类别:
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