Pilot Projects

试点项目

基本信息

  • 批准号:
    10006840
  • 负责人:
  • 金额:
    $ 44.7万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2016
  • 资助国家:
    美国
  • 起止时间:
    2016-08-05 至 2023-07-31
  • 项目状态:
    已结题

项目摘要

SUMMARY for the Pilot Project Program The design of the Pilot Project Program is based on the long-term vision of enhancing the scientific pace, collaboration, and competitiveness of the Vermont Center for Immunology and Infectious Diseases (VCIID). This is consistent with our overall objective of the Phase III COBRE program to promote the transition to an independent sustainable center that can compete for collaborative R01, P01, U19, and SBIR/STTR grants. Based on our developed research expertise during Phases I and II, and national trends in biomedical research, we have designed three categories of Pilots Projects to expand the VCIID's research portfolio: i) basic research in immunology or microbiology, ii) translational research, and iii) an entrepreneurial SPARK-VT Program to move ideas from basic research into the commercial sector through diagnostic or therapeutic platforms. Emphasis among these three categories will be given to junior investigators and collaborations, both within VCIID COBRE faculty as well as with other COBRE programs, such as the Vermont Lung Center (VLC) or the nearby Geisel/Dartmouth Medical School COBRE in Immunology/Microbiology. A rigorous application and review process will be implemented using NIH guidelines to identify the most meritorious science, and to select applicants with the greatest potential for long-term success. In addition, the Pilot Project Program will be responsive to the needs of junior faculty by providing them with a more favorable pay line, and assigned mentoring. The Specific Aims are thus: Specific Aim 1. Implement a Pilot Project Program. We will provide Pilot Project funds to VCIID faculty to secure critical data for new grants, with emphasis on collaborations with investigators in this and other COBRE programs, use of core facilities, and with the provision of personalized mentoring. Specific Aim 2. Provide rigorous evaluation of Pilot Projects to promote publications and grant submissions. We will use an NIH format of written applications followed by oral presentations of the most meritorious to the External Advisory Committee (EAC). Among those with high scientific merit, preference will be given for junior faculty and collaborating faculty. Specific Aim 3. Foster P01/U-19 working groups around common research themes of the Pilot Project Grants. Working groups with appointed leaders have been formed around common research themes in i) viral immunology, ii) metabolic regulation of the immune response, iii) computational modeling of the immune system, iv) small molecule targets for parasites, and v) sex differences in susceptibility to infectious and autoimmune diseases. These groups could receive pilot funding to get critical data needed for collaborative R01, P01, U19, or SBIR/STTR grants.
试点项目计划概述

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ monograph.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ sciAawards.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ conferencePapers.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ patent.updateTime }}

Ralph C Budd其他文献

Ralph C Budd的其他文献

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

{{ truncateString('Ralph C Budd', 18)}}的其他基金

Vermont Center for Immunobiology/Infectious Diseases (VCIID)
佛蒙特州免疫生物学/传染病中心 (VCIID)
  • 批准号:
    10395160
  • 财政年份:
    2020
  • 资助金额:
    $ 44.7万
  • 项目类别:
Metabolic Regulation of Caspases and Survival in T Cells
Caspases 的代谢调节和 T 细胞的存活
  • 批准号:
    9110491
  • 财政年份:
    2016
  • 资助金额:
    $ 44.7万
  • 项目类别:
VCIID Administrative Core
VCIID 管理核心
  • 批准号:
    10006837
  • 财政年份:
    2016
  • 资助金额:
    $ 44.7万
  • 项目类别:
Vermont Immunobiology / Infectious Diseases Center
佛蒙特州免疫生物学/传染病中心
  • 批准号:
    10006835
  • 财政年份:
    2016
  • 资助金额:
    $ 44.7万
  • 项目类别:
VERMONT IMMUNOBIOLOIGY/ INFECTIOUS DISEASES CENTER
佛蒙特州免疫生物学/传染病中心
  • 批准号:
    8360768
  • 财政年份:
    2011
  • 资助金额:
    $ 44.7万
  • 项目类别:
VERMONT IMMUNOBIOL/INFECTIOUS DIS CTR: CORE A: ADMINISTRATIVE/INTELLECTUAL CORE
佛蒙特州免疫生物学/感染性疾病 CTR:核心 A:行政/智力核心
  • 批准号:
    8167727
  • 财政年份:
    2010
  • 资助金额:
    $ 44.7万
  • 项目类别:
VERMONT IMMUNOBIOL/INFECTIOUS DIS CTR: CORE A: ADMINISTRATIVE/INTELLECTUAL CORE
佛蒙特州免疫生物学/感染性疾病 CTR:核心 A:行政/智力核心
  • 批准号:
    7959813
  • 财政年份:
    2009
  • 资助金额:
    $ 44.7万
  • 项目类别:
Vermont Immunobiology / Infectious Diseases Center
佛蒙特州免疫生物学/传染病中心
  • 批准号:
    7906346
  • 财政年份:
    2009
  • 资助金额:
    $ 44.7万
  • 项目类别:
Gamma Delta T Cells in Lyme Arthritis
莱姆关节炎中的 Gamma Delta T 细胞
  • 批准号:
    7932685
  • 财政年份:
    2009
  • 资助金额:
    $ 44.7万
  • 项目类别:
Vermont Immunobiology / Infectious Diseases Center
佛蒙特州免疫生物学/传染病中心
  • 批准号:
    7892082
  • 财政年份:
    2009
  • 资助金额:
    $ 44.7万
  • 项目类别:

相似国自然基金

Autoimmune diseases therapies: variations on the microbiome in rheumatoid arthritis
  • 批准号:
    31171277
  • 批准年份:
    2011
  • 资助金额:
    60.0 万元
  • 项目类别:
    面上项目

相似海外基金

Effects of maternal immune activation on autoimmune diseases in offsprings
母体免疫激活对后代自身免疫性疾病的影响
  • 批准号:
    23H02155
  • 财政年份:
    2023
  • 资助金额:
    $ 44.7万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Autoantibodies and antibody-secreting cells in neurological autoimmune diseases: from biology to therapy
神经性自身免疫性疾病中的自身抗体和抗体分泌细胞:从生物学到治疗
  • 批准号:
    479128
  • 财政年份:
    2023
  • 资助金额:
    $ 44.7万
  • 项目类别:
    Operating Grants
IPP: AUTOIMMUNE DISEASES STATISTICAL AND CLINICAL COORDINATING CENTER (ADSCCC)
IPP:自身免疫性疾病统计和临床协调中心 (ADSCCC)
  • 批准号:
    10788032
  • 财政年份:
    2023
  • 资助金额:
    $ 44.7万
  • 项目类别:
Biomarkers of vascular endothelial dysfunction in systemic autoimmune diseases: analysis of circulating microRNAs
系统性自身免疫性疾病中血管内皮功能障碍的生物标志物:循环 microRNA 分析
  • 批准号:
    23K14742
  • 财政年份:
    2023
  • 资助金额:
    $ 44.7万
  • 项目类别:
    Grant-in-Aid for Early-Career Scientists
NOVEL HUMORAL AND CELLULAR BIOMARKERS OF AUTOIMMUNE DISEASES CAUSED BY IMMUNOTHERAPY
免疫治疗引起的自身免疫性疾病的新型体液和细胞生物标志物
  • 批准号:
    10593224
  • 财政年份:
    2023
  • 资助金额:
    $ 44.7万
  • 项目类别:
Structural mechanisms of autoimmune diseases targeting cys-loop receptors
针对半胱氨酸环受体的自身免疫性疾病的结构机制
  • 批准号:
    10864719
  • 财政年份:
    2023
  • 资助金额:
    $ 44.7万
  • 项目类别:
Developing non-immunosuppressive immune-based therapeutics for targeted treatment of autoimmune diseases
开发非免疫抑制性免疫疗法来靶向治疗自身免疫性疾病
  • 批准号:
    10586562
  • 财政年份:
    2023
  • 资助金额:
    $ 44.7万
  • 项目类别:
Regulation of autoimmune diseases by PTPN22 phosphatase
PTPN22磷酸酶对自身免疫性疾病的调节
  • 批准号:
    23K06589
  • 财政年份:
    2023
  • 资助金额:
    $ 44.7万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Decipher and target GABA metabolism and GABA receptor-mediated signaling in autoimmune diseases
破译并靶向自身免疫性疾病中的 GABA 代谢和 GABA 受体介导的信号传导
  • 批准号:
    10623380
  • 财政年份:
    2023
  • 资助金额:
    $ 44.7万
  • 项目类别:
Targeting the long isoform of the prolactin receptor to treat autoimmune diseases and B-cell malignancies
靶向催乳素受体的长亚型来治疗自身免疫性疾病和 B 细胞恶性肿瘤
  • 批准号:
    10735148
  • 财政年份:
    2023
  • 资助金额:
    $ 44.7万
  • 项目类别:
{{ showInfoDetail.title }}

作者:{{ showInfoDetail.author }}

知道了