Administrative Core

摘要管理核心： 新墨西哥州探索性阿尔茨海默病研究中心（NM）行政核心（AC eADRC）通过召集委员会并与 NACC、NCRAD和NIA。NM eADRC为新墨西哥州的AD科学创建了一个基础设施， 农村美国印第安人（AI）社区的研究参与水平，并增加 了解血管疾病在AD和相关痴呆（AD/ADRD）中的作用， 生物标志物和神经影像学的进展。咨询委员会将确保成功完成目标 总体、临床和科学核心。咨询委员会将成立委员会，以帮助实现 NM eADRC。AC将把高级科学家与初级教师、实习生、临床实践医生和 社区卫生代表。NM eADRC的科学家们 具有丰富经验的研究人员管理大型研究项目，培训初级研究人员， 和团队合作PI是UNM神经病学的负责人，也是记忆中心的主任 和老化。作为主席，他管理了两项神经科学Cobre赠款。NM eADRC联合主任 是全国公认的AD研究人员，也是开发tau疫苗的领导者。 蛋白AC共同领导人接受过老年病学和神经病学培训，共同编辑了老年病学教科书， 神经病学，并已与当地社区和全州组织多年来， 痴呆症相关活动神经心理学将由Sadek和Prestopnik博士指导， 卡普里汉和基尔博士的神经成像一个示范/试点项目将利用社区卫生 代表和移动的MR成像，将AD研究带到部落地区，并配备移动的现场 筛选和测试（MOSST），使用MIND Research的两台移动的1.5 T MRI扫描仪 网络开发血管生物标志物的创新性工作将为血管生物标志物添加血管成分。 AD的NIA-AA标准。在UNM开发的BBB研究将提供对 炎症NM eADRC的一个主要优势是能够包括来自代表性不足的数据 少数民族在NACC，ADNI和NCRAD数据库。NM eADRC将为西南部带来一个 AD/ADRD研究和创新护理的主要中心，将利用杰出的科学 国家资源，同时更好地了解农村和少数民族的需求， 人口数量。

Abstract Administrative Core: The Administrative Core (AC) of New Mexico Exploratory Alzheimer’s Disease Research Center (NM eADRC) is critical for the management of the center by convening committees and interacting with NACC, NCRAD, and NIA. NM eADRC creates an infrastructure for AD science in New Mexico, raising the level of research participation in rural American Indian (AI) communities, and increasing the understanding of the role of vascular disease in AD and related dementias (AD/ADRD) through the use of biomarkers and advances in neuroimaging. The AC will ensure the successful completion of the aims in the Overall, Clinical and Scientific Cores. The AC will form committees to help achieve the goals of the NM eADRC. The AC will link senior scientists with junior faculty, trainees, clinical practice physicians and community health representatives (CHRs). The scientists in the NM eADRC are accomplished investigators with extensive experience managing large research projects, training junior investigators, and working as a team. The PI was head of Neurology at UNM and is director of the Center for Memory and Aging. As Chair, he managed two neuroscience CoBRE grants. The Co-Director of the NM eADRC is a nationally recognized researcher in AD and a leader in the development of a vaccine against tau protein. The AC Co-Leader is trained in geriatrics and neurology, co-edited the textbook on geriatric neurology and has engaged with local communities and state-wide organizations for many years in dementia related activities. Neuropsychology will be directed by Drs. Sadek and Prestopnik and neuroimaging by Drs. Caprihan and Kiehl. A demonstration/pilot project will use community health representatives and mobile MR imaging to bring AD research to the tribal areas with the Mobile On-Site Screening and Testing (MOSST), using the two mobile 1.5T MRI scanners at the MIND Research Network. The innovative work on developing vascular biomarkers will add a vascular component to the NIA-AA criterial for AD. BBB studies developed at UNM will provide insight into mechanisms of inflammation. A major advantage of the NM eADRC is the ability to include data from underrepresented minorities in the NACC, ADNI, and NCRAD databases. The NM eADRC will bring to the southwest a major center for research and innovative care in AD/ADRD that will utilize the outstanding scientific resources in the state, while building a greater understanding of the needs of rural and minority populations.