权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Administrative Core

行政核心

基本信息

批准号：
10038021
负责人：
Gary Allen Rosenberg
金额：
$ 30.78万
依托单位：
UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-08-01 至 2023-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10038021
关键词：
Aging Alzheimer&apos s Disease Alzheimer&apos s disease related dementia American Indians Area Basic Science Biological Markers Blood Blood Vessels Budgets Caring Chairperson Clinical Cognitive Collaborations Communication Communities Community Health Consent Data Data Set Databases Dementia Diagnosis Elderly Ensure Event Faculty Funding Funding Mechanisms Geriatrics Goals Government Officials Grant Guidelines Head Health Occupations Human Image Image Analysis Imaging Device Incidence Inflammation Information Systems Infrastructure Link Magnetic Resonance Imaging Memory Mentorship Methods Mind-Body Method Molecular Neurology Neuropsychology Neurosciences New Mexico Newsletter Patient Recruitments Physicians Pilot Projects Population Prevalence Procedures Process Pueblo Race Research Research Personnel Research Project Grants Resources Role Rural Minority Science Scientist Senior Scientist Services Site State Government Students Testing Textbooks Time Tissue Sample Training Translational Research Trust Underrepresented Minority United States National Institutes of Health Universities Vascular Diseases Work advocacy organizations clinical practice community organizations data submission early-career faculty experience health care service innovation insight interest medical schools meetings member neuroimaging next generation outreach programs quality assurance ranpirnase rural Americans screening service providers social media tau Proteins training opportunity transmission process undergraduate student urban Native American vaccine development vascular factor web site

项目摘要

Abstract Administrative Core: The Administrative Core (AC) of New Mexico Exploratory Alzheimer’s Disease Research Center (NM eADRC) is critical for the management of the center by convening committees and interacting with NACC, NCRAD, and NIA. NM eADRC creates an infrastructure for AD science in New Mexico, raising the level of research participation in rural American Indian (AI) communities, and increasing the understanding of the role of vascular disease in AD and related dementias (AD/ADRD) through the use of biomarkers and advances in neuroimaging. The AC will ensure the successful completion of the aims in the Overall, Clinical and Scientific Cores. The AC will form committees to help achieve the goals of the NM eADRC. The AC will link senior scientists with junior faculty, trainees, clinical practice physicians and community health representatives (CHRs). The scientists in the NM eADRC are accomplished investigators with extensive experience managing large research projects, training junior investigators, and working as a team. The PI was head of Neurology at UNM and is director of the Center for Memory and Aging. As Chair, he managed two neuroscience CoBRE grants. The Co-Director of the NM eADRC is a nationally recognized researcher in AD and a leader in the development of a vaccine against tau protein. The AC Co-Leader is trained in geriatrics and neurology, co-edited the textbook on geriatric neurology and has engaged with local communities and state-wide organizations for many years in dementia related activities. Neuropsychology will be directed by Drs. Sadek and Prestopnik and neuroimaging by Drs. Caprihan and Kiehl. A demonstration/pilot project will use community health representatives and mobile MR imaging to bring AD research to the tribal areas with the Mobile On-Site Screening and Testing (MOSST), using the two mobile 1.5T MRI scanners at the MIND Research Network. The innovative work on developing vascular biomarkers will add a vascular component to the NIA-AA criterial for AD. BBB studies developed at UNM will provide insight into mechanisms of inflammation. A major advantage of the NM eADRC is the ability to include data from underrepresented minorities in the NACC, ADNI, and NCRAD databases. The NM eADRC will bring to the southwest a major center for research and innovative care in AD/ADRD that will utilize the outstanding scientific resources in the state, while building a greater understanding of the needs of rural and minority populations.

行政核心：