Administrative Core

摘要行政核心： 新墨西哥州探索性阿尔茨海默病研究中心 (NM) 的行政核心 (AC) eADRC）通过召集委员会并与各方互动对于中心的管理至关重要 NACC、NCRAD 和 NIA。 NM eADRC 在新墨西哥州创建 AD 科学基础设施，筹集资金 美洲印第安人农村社区的研究参与水平，并提高 通过使用了解血管疾病在 AD 和相关痴呆 (AD/ADRD) 中的作用 生物标志物和神经影像学的进展。审计委员会将确保成功完成目标 总体、临床和科学核心。审计委员会将成立委员会来帮助实现审计委员会的目标 NM eADRC。 AC 将把高级科学家与初级教员、实习生、临床实践医生和 社区卫生代表 (CHR)。 NM eADRC 的科学家们已经完成了 具有管理大型研究项目、培训初级研究人员的丰富经验的研究人员， 并作为一个团队工作。该 PI 是新墨西哥大学神经病学的负责人，也是记忆中心的主任 和老化。作为主席，他管理了两项神经科学 CoBRE 资助。 NM eADRC 联合主任 是全国公认的 AD 研究者，也是 tau 疫苗开发的领导者 蛋白质。 AC 联合负责人接受过老年病学和神经病学培训，共同编辑了老年病学教科书 神经病学，并与当地社区和全州组织合作多年 痴呆症相关活动。神经心理学将由博士指导。萨德克和普雷斯托尼克以及 神经影像学博士。卡普里汉和基尔。示范/试点项目将利用社区卫生 代表和移动 MR 成像，通过移动现场将 AD 研究带到部落地区 筛查和测试 (MOSST)，使用 MIND Research 的两台移动 1.5T MRI 扫描仪 网络。开发血管生物标志物的创新工作将为血管成分添加到 NIA-AA AD 标准。新墨西哥州开展的 BBB 研究将深入了解 BBB 的机制 炎症。 NM eADRC 的一个主要优势是能够包含来自代表性不足的数据 NACC、ADNI 和 NCRAD 数据库中的少数群体。 NM eADRC 将为西南地区带来 AD/ADRD 研究和创新护理的主要中心，将利用杰出的科学技术 国家的资源，同时加深对农村和少数民族需求的了解 人口。

Abstract Administrative Core: The Administrative Core (AC) of New Mexico Exploratory Alzheimer’s Disease Research Center (NM eADRC) is critical for the management of the center by convening committees and interacting with NACC, NCRAD, and NIA. NM eADRC creates an infrastructure for AD science in New Mexico, raising the level of research participation in rural American Indian (AI) communities, and increasing the understanding of the role of vascular disease in AD and related dementias (AD/ADRD) through the use of biomarkers and advances in neuroimaging. The AC will ensure the successful completion of the aims in the Overall, Clinical and Scientific Cores. The AC will form committees to help achieve the goals of the NM eADRC. The AC will link senior scientists with junior faculty, trainees, clinical practice physicians and community health representatives (CHRs). The scientists in the NM eADRC are accomplished investigators with extensive experience managing large research projects, training junior investigators, and working as a team. The PI was head of Neurology at UNM and is director of the Center for Memory and Aging. As Chair, he managed two neuroscience CoBRE grants. The Co-Director of the NM eADRC is a nationally recognized researcher in AD and a leader in the development of a vaccine against tau protein. The AC Co-Leader is trained in geriatrics and neurology, co-edited the textbook on geriatric neurology and has engaged with local communities and state-wide organizations for many years in dementia related activities. Neuropsychology will be directed by Drs. Sadek and Prestopnik and neuroimaging by Drs. Caprihan and Kiehl. A demonstration/pilot project will use community health representatives and mobile MR imaging to bring AD research to the tribal areas with the Mobile On-Site Screening and Testing (MOSST), using the two mobile 1.5T MRI scanners at the MIND Research Network. The innovative work on developing vascular biomarkers will add a vascular component to the NIA-AA criterial for AD. BBB studies developed at UNM will provide insight into mechanisms of inflammation. A major advantage of the NM eADRC is the ability to include data from underrepresented minorities in the NACC, ADNI, and NCRAD databases. The NM eADRC will bring to the southwest a major center for research and innovative care in AD/ADRD that will utilize the outstanding scientific resources in the state, while building a greater understanding of the needs of rural and minority populations.