Development of a Novel Personalized Risk Assessment for College Alcohol Prevention

开发一种新颖的个性化大学酒精预防风险评估

• 批准号: 10013117
• 负责人: DANIELLE M DICK
• 金额: $ 20.34万
• 依托单位: VIRGINIA COMMONWEALTH UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-10 至 2022-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10013117
• 关键词: Address; Administrator; Adopted; Alcohol consumption; Alcohol or Other Drugs use; Behavioral; Control Groups; Data; Development; Drug usage; Effectiveness; Emotional; Etiology; Feedback; Focus Groups; Foundations; Frequencies; Goals; Health; Health Benefit; Human Resources; Individual; Infrastructure; Injury; Institutes; Intervention; Knowledge; Lead; Legal; Life Cycle Stages; Measures; Mental Health; Pathway interactions; Phase; Physiological; Policies; Population; Positioning Attribute; Postdoctoral Fellow; Preventive Intervention; Procedures; Recommendation; Reporting; Research; Research Personnel; Research Project Grants; Resources; Risk; Risk Assessment; Risk Factors; Science; Students; Surveys; Testing; Time; Translating; Treatment Efficacy; Universities; Work; adverse outcome; alcohol and other drug; alcohol misuse; alcohol prevention; assault; base; binge drinking; brief motivational intervention; college; college drinking; cost; evidence base; illicit drug use; innovation; intervention program; novel; personalized medicine; prevent; randomized controlled design; service providers; sexual encounter; substance use prevention; tool; university student

PROJECT SUMMARY The primary goal of this R34 proposal is to conduct pilot testing of a new intervention for college student substance use. Risky substance use among college students is widespread, and associated with numerous adverse consequences. Although brief motivational interventions (BMIs) have been widely adopted by colleges to address risky alcohol use, most studies find only small to moderate effects, with a review of college student drinking interventions noting that “significant enhancement of personalized feedback intervention efficacy has not been observed in over 15 years of study” (Miller et al. 2015). Current interventions focus on students’ current substance use, and largely do not address underlying risk factors and the pathways that lead students to use. There is compelling evidence that students use/misuse alcohol for different reasons, and that externalizing, internalizing, and physiological factors strongly predict college students’ substance use and problems. The fast-growing field of personalized medicine is harnessing our growing knowledge about underlying etiological factors to provide individuals with specific information about their unique risk profiles and personalized recommendations, in order to motivate and enable individuals to better self-regulate their health. With this R34 we will evaluate an on-line Personalized Risk Assessment (PRA) for college students that provides feedback about the individual’s specific core underlying risk factors for substance use, and how these factors can lead to substance problems, along with personalized recommendations and resources. The project will capitalize on foundational work from our unique, on-going university-wide research project (Spit for Science; S4S), in which >12,000 students (~70% of five years of incoming freshmen thus far) are being followed longitudinally with surveys assessing substance use and related factors across the college years. From these data we have identified risk factors most strongly related to college students’ substance use, and have developed an associated research center that brings together S4S researchers with university administrators and student affairs personnel to translate this research into enhanced university programming and policy. Making use of this extant collaborative network, we will (Aim 1) finalize the editing and programming of our on- line personalized risk assessment platform; (Aim 2) systematically refine the risk questions and feedback tools by conducting four focus groups (N= 40) and an open trial (N=40) with college students with varying risk profiles, and one focus group with college wellness staff and service providers; and (Aim 3) preliminarily evaluate the efficacy of the PRA in comparison to an assessment only control group, a standard BMI, and a PRA+BMI condition to test whether there are additive or interactive effects, using a randomized controlled design of N = 300 freshman with measures of substance use and academic functioning collected at 3 time points across the freshman year. College represents a unique opportunity to intervene and have positive life- course altering health benefits for a significant, and increasingly diverse portion of the population.

项目总结 R34提案的主要目标是对大学生的新干预措施进行试点测试 物质使用。大学生中使用危险物质的情况很普遍，并与许多 不利的后果。尽管简短的动机干预(BMI)已被大学广泛采用 为了解决高风险饮酒的问题，大多数研究发现只有轻微到中度的影响，并对大学生进行了回顾 饮酒干预注意到“个性化反馈干预效果的显著增强 在超过15年的研究中没有被观察到“(Miller等人)。2015年)。目前的干预措施主要集中在学生的 目前的物质使用，很大程度上没有解决潜在的风险因素和导致学生 来使用。有令人信服的证据表明，学生出于不同的原因使用/滥用酒精，而且 外化因素、内化因素和生理因素对大学生物质使用行为有较强的预测力 有问题。快速增长的个性化医疗领域正在利用我们日益增长的知识 潜在的病因学因素，为个人提供有关其独特风险概况和 个性化建议，以激励和使个人能够更好地自我调节自己的健康。 利用这一R34，我们将评估针对大学生的在线个性化风险评估(PRA)， 提供有关个人使用物质的特定核心潜在风险因素的反馈，以及这些因素如何 除了个性化的建议和资源，各种因素都可能导致实质性的问题。该项目 将利用我们独特的、正在进行的大学范围内的研究项目(为科学吐口水； S4)，其中12,000名学生(约占到目前五年新生总数的70%)被跟踪 纵向调查，评估大学期间的物质使用情况和相关因素。从这些 我们已经确定了与大学生药物使用最密切相关的风险因素，并有 开发了一个联合研究中心，将S4S研究人员与大学管理人员聚集在一起 和学生事务人员将这项研究转化为增强的大学规划和政策。 利用这个现有的协作网络，我们将(目标1)完成我们的On- LINE个性化风险评估平台；(目标2)系统细化风险问题和反馈工具 通过对不同风险的大学生进行四个焦点小组(N=40)和开放试验(N=40) 简介，以及一个由大学保健工作人员和服务提供者组成的重点小组；(目标3)初步 通过与仅评估对照组、标准BMI和 PRA+BMI条件检验是否存在相加或交互效应，使用随机对照 N=300名大一新生3次使用物质使用和学习功能量表的设计 一年级的分数。大学代表着一个独特的介入和拥有积极生活的机会- 改变了相当大的、日益多样化的人口部分的健康福利。