Development of a Novel Personalized Risk Assessment for College Alcohol Prevention

项目摘要 这项R34提案的主要目标是为大学生进行新干预措施的试点测试。 物质使用。大学生中危险物质的使用是普遍的，与许多 不良后果。虽然简短的动机干预（BMI）已被广泛采用的大学 为了解决危险的酒精使用，大多数研究发现只有小到中度的影响， 饮酒干预措施指出，“个性化反馈干预效果的显着增强， 在超过15年的研究中未观察到”（米勒等人，2015）。目前的干预措施侧重于学生的 目前的物质使用，并在很大程度上没有解决潜在的风险因素和途径，导致学生 使用.有令人信服的证据表明，学生使用/滥用酒精的原因不同， 外化、内化和生理因素强烈预测大学生的物质使用， 问题快速发展的个性化医疗领域正在利用我们不断增长的知识， 潜在的病因因素，为个人提供关于其独特风险状况的具体信息， 个性化的建议，以激励和使个人能够更好地自我调节他们的健康。 有了这个R34，我们将评估一个在线个性化风险评估（PRA）的大学生， 提供有关个人物质使用的特定核心潜在风险因素的反馈，以及这些风险因素如何 因素可能导致实质性问题，沿着个性化推荐和资源。项目 将利用我们独特的，正在进行的大学范围内的研究项目（吐科学; S4 S），其中超过12，000名学生（迄今为止五年新生的约70%）正在接受随访 纵向与调查评估物质使用和相关因素在大学几年。从这些 我们已经确定了与大学生物质使用最密切相关的风险因素， 建立了一个联合研究中心，将S4 S研究人员与大学管理人员聚集在一起 和学生事务人员将这项研究转化为加强大学规划和政策。 利用这个现有的合作网络，我们将（目标1）完成编辑和编制我们的关于 线下个性化风险评估平台;（目标2）系统化完善风险问题和反馈工具 通过进行四个焦点小组（N= 40）和一项开放试验（N=40）， 简介，和一个重点小组与大学健康工作人员和服务提供者;和（目标3）初步 评价PRA与仅评估对照组、标准BMI和 PRA+BMI条件，以检验是否存在累加效应或交互效应，使用随机对照 采用随机设计，对300名大学新生进行了3次物质使用和学业功能测量 在大一的时候。大学代表了一个独特的机会，干预和积极的生活- 改变健康利益的过程，为人口的一个重要的，越来越多样化的部分。

PROJECT SUMMARY The primary goal of this R34 proposal is to conduct pilot testing of a new intervention for college student substance use. Risky substance use among college students is widespread, and associated with numerous adverse consequences. Although brief motivational interventions (BMIs) have been widely adopted by colleges to address risky alcohol use, most studies find only small to moderate effects, with a review of college student drinking interventions noting that “significant enhancement of personalized feedback intervention efficacy has not been observed in over 15 years of study” (Miller et al. 2015). Current interventions focus on students’ current substance use, and largely do not address underlying risk factors and the pathways that lead students to use. There is compelling evidence that students use/misuse alcohol for different reasons, and that externalizing, internalizing, and physiological factors strongly predict college students’ substance use and problems. The fast-growing field of personalized medicine is harnessing our growing knowledge about underlying etiological factors to provide individuals with specific information about their unique risk profiles and personalized recommendations, in order to motivate and enable individuals to better self-regulate their health. With this R34 we will evaluate an on-line Personalized Risk Assessment (PRA) for college students that provides feedback about the individual’s specific core underlying risk factors for substance use, and how these factors can lead to substance problems, along with personalized recommendations and resources. The project will capitalize on foundational work from our unique, on-going university-wide research project (Spit for Science; S4S), in which >12,000 students (~70% of five years of incoming freshmen thus far) are being followed longitudinally with surveys assessing substance use and related factors across the college years. From these data we have identified risk factors most strongly related to college students’ substance use, and have developed an associated research center that brings together S4S researchers with university administrators and student affairs personnel to translate this research into enhanced university programming and policy. Making use of this extant collaborative network, we will (Aim 1) finalize the editing and programming of our on- line personalized risk assessment platform; (Aim 2) systematically refine the risk questions and feedback tools by conducting four focus groups (N= 40) and an open trial (N=40) with college students with varying risk profiles, and one focus group with college wellness staff and service providers; and (Aim 3) preliminarily evaluate the efficacy of the PRA in comparison to an assessment only control group, a standard BMI, and a PRA+BMI condition to test whether there are additive or interactive effects, using a randomized controlled design of N = 300 freshman with measures of substance use and academic functioning collected at 3 time points across the freshman year. College represents a unique opportunity to intervene and have positive life- course altering health benefits for a significant, and increasingly diverse portion of the population.