Development of a Novel Personalized Risk Assessment for College Alcohol Prevention

开发一种新颖的个性化大学酒精预防风险评估

• 批准号: 10013117
• 负责人: DANIELLE M DICK
• 金额: $ 20.34万
• 依托单位: VIRGINIA COMMONWEALTH UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-10 至 2022-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10013117
• 关键词: Address; Administrator; Adopted; Alcohol consumption; Alcohol or Other Drugs use; Behavioral; Control Groups; Data; Development; Drug usage; Effectiveness; Emotional; Etiology; Feedback; Focus Groups; Foundations; Frequencies; Goals; Health; Health Benefit; Human Resources; Individual; Infrastructure; Injury; Institutes; Intervention; Knowledge; Lead; Legal; Life Cycle Stages; Measures; Mental Health; Pathway interactions; Phase; Physiological; Policies; Population; Positioning Attribute; Postdoctoral Fellow; Preventive Intervention; Procedures; Recommendation; Reporting; Research; Research Personnel; Research Project Grants; Resources; Risk; Risk Assessment; Risk Factors; Science; Students; Surveys; Testing; Time; Translating; Treatment Efficacy; Universities; Work; adverse outcome; alcohol and other drug; alcohol misuse; alcohol prevention; assault; base; binge drinking; brief motivational intervention; college; college drinking; cost; evidence base; illicit drug use; innovation; intervention program; novel; personalized medicine; prevent; randomized controlled design; service providers; sexual encounter; substance use prevention; tool; university student

PROJECT SUMMARY The primary goal of this R34 proposal is to conduct pilot testing of a new intervention for college student substance use. Risky substance use among college students is widespread, and associated with numerous adverse consequences. Although brief motivational interventions (BMIs) have been widely adopted by colleges to address risky alcohol use, most studies find only small to moderate effects, with a review of college student drinking interventions noting that “significant enhancement of personalized feedback intervention efficacy has not been observed in over 15 years of study” (Miller et al. 2015). Current interventions focus on students’ current substance use, and largely do not address underlying risk factors and the pathways that lead students to use. There is compelling evidence that students use/misuse alcohol for different reasons, and that externalizing, internalizing, and physiological factors strongly predict college students’ substance use and problems. The fast-growing field of personalized medicine is harnessing our growing knowledge about underlying etiological factors to provide individuals with specific information about their unique risk profiles and personalized recommendations, in order to motivate and enable individuals to better self-regulate their health. With this R34 we will evaluate an on-line Personalized Risk Assessment (PRA) for college students that provides feedback about the individual’s specific core underlying risk factors for substance use, and how these factors can lead to substance problems, along with personalized recommendations and resources. The project will capitalize on foundational work from our unique, on-going university-wide research project (Spit for Science; S4S), in which >12,000 students (~70% of five years of incoming freshmen thus far) are being followed longitudinally with surveys assessing substance use and related factors across the college years. From these data we have identified risk factors most strongly related to college students’ substance use, and have developed an associated research center that brings together S4S researchers with university administrators and student affairs personnel to translate this research into enhanced university programming and policy. Making use of this extant collaborative network, we will (Aim 1) finalize the editing and programming of our on- line personalized risk assessment platform; (Aim 2) systematically refine the risk questions and feedback tools by conducting four focus groups (N= 40) and an open trial (N=40) with college students with varying risk profiles, and one focus group with college wellness staff and service providers; and (Aim 3) preliminarily evaluate the efficacy of the PRA in comparison to an assessment only control group, a standard BMI, and a PRA+BMI condition to test whether there are additive or interactive effects, using a randomized controlled design of N = 300 freshman with measures of substance use and academic functioning collected at 3 time points across the freshman year. College represents a unique opportunity to intervene and have positive life- course altering health benefits for a significant, and increasingly diverse portion of the population.

项目概要 R34 提案的主要目标是对大学生的新干预措施进行试点测试 物质的使用。大学生中危险物质的使用很普遍，并且与许多 不良后果。尽管简短的动机干预（BMI）已被大学广泛采用 为了解决危险的饮酒问题，大多数研究仅发现小到中度的影响，并对大学生进行了审查 饮酒干预指出“个性化反馈干预效果的显着增强 在超过 15 年的研究中尚未观察到“（Miller 等人，2015）。当前的干预措施侧重于学生的 当前的物质使用，很大程度上没有解决潜在的风险因素和导致学生的途径 使用。有令人信服的证据表明学生出于不同的原因使用/滥用酒精，并且 外化、内化和生理因素强烈预测大学生的物质使用和 问题。快速发展的个性化医疗领域正在利用我们不断增长的知识 潜在的病因学因素，为个人提供有关其独特风险状况的具体信息和 个性化建议，以激励并使个人能够更好地自我调节自己的健康。 通过此 R34，我们将为大学生进行在线个性化风险评估 (PRA)， 提供有关个人物质使用的特定核心潜在风险因素的反馈，以及这些因素如何 各种因素以及个性化的建议和资源都可能导致实质性问题。项目 将利用我们独特的、正在进行的全校研究项目（Spit for Science； S4S），其中超过 12,000 名学生（迄今为止，约占五年级新生的 70%）正在接受跟踪 纵向评估大学期间药物使用和相关因素的调查。从这些 我们已经根据数据确定了与大学生药物滥用最密切相关的风险因素，并且 建立了一个联合研究中心，将 S4S 研究人员与大学管理人员聚集在一起 和学生事务人员将这项研究转化为增强的大学规划和政策。 利用这个现有的协作网络，我们将（目标 1）完成我们的on- 线路个性化风险评估平台； （目标2）系统地完善风险问题和反馈工具 通过对具有不同风险的大学生进行四个焦点小组（N = 40）和公开试验（N = 40） 个人资料，以及一个由大学健康工作人员和服务提供商组成的焦点小组；和（目标 3）初步 与仅评估对照组、标准 BMI 和 PRA+BMI条件来测试是否存在相加效应或交互效应，使用随机对照 设计了 N = 300 名新生，并在 3 次收集了物质使用和学业功能的测量结果 整个大一学年的分数。大学代表了一个独特的干预和积极生活的机会- 过程改变了很大一部分且日益多样化的人口的健康益处。