Socio-Cultural Stress Profiles, Stress Responses, and Health in Mexican American Adolescents

墨西哥裔美国青少年的社会文化压力概况、压力反应和健康

• 批准号: 10023192
• 负责人: SU YEONG KIM
• 金额: $ 20.14万
• 依托单位: UNIVERSITY OF TEXAS AT AUSTIN
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-23 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10023192
• 关键词: Academic achievement; Acute; Adolescence; Adolescent; Adult; Affect; Alcohol or Other Drugs use; Attention; Award; Behavior; Behavioral; Blood Pressure; C-reactive protein; Child; Chronic; Complex; Data; Data Collection; Development; Diabetes Mellitus; Discrimination; Economically Deprived Population; Economics; Educational Status; Family; Foreigner; Future; Glycosylated hemoglobin A; Goals; Grant; Health; Hispanics; Hydrocortisone; Immigrant; Incidence; Individual; Inflammation; Interleukin-6; Language; Latino; Legal Status; Life; Limited English Proficiency; Link; Low income; Measures; Mediating; Medical; Mental Depression; Mexican; Mexican Americans; Mission; Modeling; Obesity; Outcome; Parents; Participant; Pathway interactions; Patient Self-Report; Phase; Physiological; Plague; Population; Poverty; Preventive Intervention; Process; Public Health; Recovery; Research; Research Personnel; Resources; Risk; Risk Factors; Sampling; Skin; Sleep; Social Environment; Source; Strategic Planning; Stress; Testing; Time; Translating; Trier Social Stress Test; United States National Institutes of Health; Variant; Wrist; adolescent health; adolescent health outcomes; biological adaptation to stress; cardiometabolic risk; cardiovascular disorder risk; cohort; diabetes risk; experience; health disparity; high risk; high school; improved; junior high school; low socioeconomic status; peer; physical conditioning; prospective; psychosocial; resilience; response; social; social culture; social stressor; stressor; success; virtual

This project is in response to PA-17-042 and examines the longitudinal influence of socio-cultural stressors, physiological and behavioral stress responses to these stressors, and health outcomes of adolescents in Mexican immigrant families. Recognizing the challenging social environments in which adolescents in Mexican immigrant families are embedded, this project creates socio-cultural stress profiles comprised of economic stress, discrimination and foreigner stress, and language brokering experiences (in which children translate between English and Spanish for their English-limited parents). Our ongoing research with adolescents in Mexican immigrant families has identified three socio-cultural stress profiles (moderate, protective, risk), three stable profiles over time (stable moderate, stable protective, stable risk), and two socio-cultural change profiles over time (improved, declined). The proposed project builds on a successful study of adolescents in Mexican immigrant families (PI: Kim, NSF, BCS-0956123 and BCS-651128; NIH, R03HD060045) to examine, prospectively, the influence of socio-cultural stress profiles in middle school alone, as well as continuity and change in socio-cultural stress profiles from middle school to high school, on adolescent health (Aim 1). Specifically, this grant will allow the research team to add measures of physiological health outcomes, namely inflammation (IL-6, C-reactive protein) and diabetes risk (hemoglobin A1c). We will also test a pathways model, to determine whether socio-cultural stress profiles are associated with adaptive or maladaptive physiological and behavioral stress responses that influence health (Aim 2). Further, we propose to test whether the associations from socio-cultural stress profiles to stress responses to health outcomes are exacerbated or mitigated through various moderators, including personal (resilience, parent support) and cultural (family obligation) resources, stress related to legal status, and language brokering places and content (Aim 3). Physiological stress response will be assessed via cortisol. Acute cortisol will be assessed by measuring reactivity and recovery to an adaptation of the Trier Social Stress Test, in which adolescents verbally translate a medical document for their parents. Day-to-day cortisol will also be measured. Substance use and sleep are self-reported daily, and motionlogger watches worn on the wrist provide an objective assessment of sleep. This study is very much in line with the 2016-2020 NIH strategic plan of studying normative populations to detect points for preventive interventions to reduce health disparities. It does so by studying socio-cultural stress profiles that include language brokering experiences, a common phenomenon in low-income Mexican immigrant families that has received little attention to date. We examine the complex conditions under which socio-cultural profiles can function as sources of both risk and protection for adolescents. This project has the potential to uncover processes and practices that can reduce persistent health disparities in Mexican immigrant families.

本项目是对PA-17-042的回应，并检查了社会文化压力的纵向影响， 这些压力源的生理和行为压力反应，以及青少年的健康结果， 墨西哥移民家庭认识到墨西哥青少年所处的具有挑战性的社会环境 移民家庭是嵌入式的，该项目创造了社会文化压力的情况，包括经济 压力，歧视和外国人的压力，以及语言中介经验（儿童翻译 英语和西班牙语之间为他们的英语有限的父母）。我们正在进行的青少年研究， 墨西哥移民家庭已经确定了三种社会文化压力概况（中度，保护性，风险），三个 随着时间的推移稳定的概况（稳定的中度、稳定的保护性、稳定的风险），以及两种社会文化变化概况 随着时间的推移（改善，下降）。拟议的项目建立在对墨西哥青少年的成功研究的基础上 移民家庭（PI：Kim，NSF，BCS-0956123和BCS-651128; NIH，R 03 HD 060045）进行检查， 前瞻性地，社会文化压力的影响，仅在中学，以及连续性和 从初中到高中，青少年健康方面的社会文化压力变化（目标1）。 具体来说，这笔赠款将允许研究小组增加生理健康结果的措施，即 炎症（IL-6，C-反应蛋白）和糖尿病风险（血红蛋白A1 c）。我们还将测试一个路径模型， 以确定社会文化压力是否与适应性或适应不良的生理 和影响健康的行为压力反应（目标2）。此外，我们建议测试是否 社会文化压力状况与对健康结果的压力反应之间的关联加剧或 通过各种调节因素缓解，包括个人（复原力、父母支持）和文化（家庭） 义务）资源，与法律的地位有关的重音，以及语言中介位置和内容（目标3）。 将通过皮质醇评估生理应激反应。急性皮质醇将通过测量 对特里尔社会压力测试的适应性反应和恢复，其中青少年口头翻译 给父母的医疗文件还将测量每日皮质醇。物质使用和睡眠是 每天自我报告，戴在手腕上的motionlogger手表提供了一个客观的睡眠评估。这 这项研究非常符合2016-2020年NIH研究规范人群的战略计划， 为减少健康差距采取预防性干预措施的要点。它通过研究社会文化压力来做到这一点 包括语言中介经验的个人资料，这是低收入墨西哥人的一种常见现象， 移民家庭至今很少受到关注。我们研究了复杂的条件下， 社会文化概况可以成为青少年的风险和保护来源。该项目具有 发现可以减少墨西哥移民持续健康差异的过程和做法的潜力 家庭