Support for Toxicological Data for the National Toxicology Program Subproject 2 (Support for Cancer Research by NTP)

支持毒物数据合同的目的是让承包商为工作人员提供应用可靠的科学和毒理学原理以及深入了解NTP毒理学研究设计的能力，以支持从NTP毒理学研究获取数据，整合研究和毒理领域的数据，并以有意义的格式展示数据，供NTP科学家、其他政府机构和公众决策使用。 国家毒理学计划(NTP)是一个跨部门计划，总部设在NIEHS，由卫生与公众服务部部长设立，目的是向监管和研究机构以及公众提供有关潜在有毒化学物质的信息，协调毒理学研究和测试活动，并加强毒理学的科学基础。 该合同支持以符合公平标准的安全方式存储NTP数据的数据管理流程，这意味着数据是可查找、可用、可解释和可重复使用的。数据存储在Oracle数据库中，然后格式化以供NTP报告。元数据(有关数据的数据)在Oracle中捕获并共享。合同还支持用户查阅这些数据以进行交叉研究查询和其他调查。合同支持设计、开发和交付访问和查询数据的工具。承包商遵守政府的安全政策，并确保预先决定的数据是安全的，只有授权用户才能使用。NTP使用LIMS系统NTP Provantis收集数据，合同向NTP和合同员工提供有关使用NTP Provantis以符合NTP预期的科学建议。

The objective of the Support for Toxicological Data contract is for Contractor to provide staff with the ability to apply sound scientific and toxicological principles and an intimate knowledge of NTP toxicological study designs to support the acquisition of data from NTP toxicological studies, the integration of the data across studies and toxicological domains, and the presentation of the data in a meaningful format for use in decision-making by NTP scientists, other government agencies and the public at large. The National Toxicology Program (NTP) is an interagency program headquartered at NIEHS and was established by the Secretary of Health and Human Services to provide information about potentially toxic chemicals to regulatory and research agencies and the public, coordinate toxicology research and testing activities and strengthen the science base in toxicology. The Contract supports the data management processes that house NTP data in a secure way compatible with FAIR standards, meaning that the data are Findable, Available, Interpretable and Reusable. The data are stored in an Oracle database and then formatted for reporting by the NTP. Metadata (data about the data) are captured in Oracle and shared. The Contract also supports user access to these data for cross-study queries and other investigations. Contract supports the design, development and delivery of tools to access and query data. Contractor adheres to security policy of the government and ensures that predecisional data are secure and available only to authorized users. NTP uses a LIMS system, NTP Provantis, to collect data and Contract provides scientific advice to NTP and contract staff about using NTP Provantis in alignment with NTP Expectations.