North Carolina Translational and Clinical Science Institute (NC TraCS) KL2

一、机构职业发展核心摘要 UNC/TraCS KL2是我们塑造初级翻译发展的旗舰计划 科学家将成为首席研究员和研究领导者。自成立以来，我们已经资助了63 学者：目前有15人在KL2中获得资助，48人已经完成了该计划。在这48个人中，有46个是 资助学术研究人员；一个是临床医生；一个是工业界的研究职位。我们成功地实现了 我们73%的毕业生获得了可观的(超过10万美元)奖学金，这一事实证明了这一点 对于一笔赠款)，独立的私人投资基金在他们开始KL2的54个月内。我们的学者代表6人 学校和17个系，这种多样性不仅使这一KL2有别于其他 校园，但也鼓励和促进学者之间的翻译合作 否则就会横穿道路。这个非常成功的项目植根于团队科学的理念。 学科、学校和中心/研究所；一支致力于工作的杰出的专家教员队伍 与导师和学者密切合作，作为教师发展协调团队方法的一部分；计划 与CTSA计划不断发展的科学和方案优先事项保持同步的领导力；以及 一种大学文化，我们以前的学者们愿意继续参与其中，并提供时间和专业知识 回到项目中，作为榜样、导师和合作者。 展望未来，KL2计划正在适应我们申请者群体不断变化的性质和不断发展的 通过个性化培训取代必修的两年制课程，培养翻译人才 由学者与KL2项目教职员工及其导师合作开发的路径。此外，我们 建立了KL2校友咨询小组，KL2毕业生在小组中提供关于培训的反馈 关于新内容的组件和建议，或重新设计当前内容的交付方式。其他变化包括 增加与CTSA联盟的合作活动，整合NCATS等新倡议 将试验创新网络和TraCS劳动力发展计划纳入培训活动，扩大 指导活动，并引入一套科学和研究领导能力。目标1： 培训KL2学者将他们的学科专业知识应用于翻译科学，并为他们配备 创建和维持变革性跨学科所需的战略思维和管理技能 翻译研究项目在快速变化的环境中。目标2：为KL2学者提供 指导他们自己的研究团队成员以及下一代调查人员的技能。 对于希望参与共享学习、同行评审的早期研究人员来说，TRACS是一个真正的“家” 最重要的是，发展一个同龄人小组，鼓励创新、弹性和留住 科学。我们的KL2计划为学者们提供了使他们能够超越方法论的经验 这是一门新的科学和技术领域的研究成果，它吸收了其他学科的概念，并产生了真正具有变革性的翻译科学。

I. Institutional Career Development Core Abstract The UNC/TraCS KL2 is the flagship program through which we shape the development of junior translational scientists to become Principal Investigators and research leaders. Since our inception, we have funded 63 Scholars: 15 are currently supported on the KL2, and 48 have completed the Program. Of these 48, 46 are funded academic investigators; one is a clinician; and one holds a research position in industry. Our success to date is exemplified by the fact that 73% of our “graduated” Scholars have received significant (over $100,000 for a single grant) independent PI funding within 54 months of their starting the KL2. Our Scholars represent 6 Schools and 17 departments, a diversity that not only distinguishes this KL2 from other training programs on campus, but also encourages and facilitates translational collaborations among Scholars who might not otherwise cross paths. This highly successful program is grounded in a philosophy of team science across disciplines, schools, and centers/institutes; an outstanding corps of expert faculty who are committed to work closely with the mentors and Scholars as part of a coordinated team approach to faculty development; program leadership that keeps abreast of the evolving scientific and programmatic priorities of the CTSA Program; and a collegial culture in which our former Scholars willingly continue to be engaged and give time and expertise back to the program as role models, mentors, and collaborators. Going forward, the KL2 Program is adapting to the changing nature of our applicant pool and the evolving translational workforce pipeline by replacing the mandatory two-year curriculum with personalized training pathways developed by Scholars in collaboration with KL2 program faculty and their mentors. In addition, we have established the KL2 Alumni Advisory Team, in which KL2 graduates provide feedback about training components and advice on new content or redesign of how current content is delivered. Other changes include increasing collaborative activities with the CTSA Consortium, integrating new initiatives such as the NCATS Trial Innovation Network and TraCS Workforce Development Program into training activities, expanding activities in mentoring, and introducing a set of competencies in scientific and research leadership. Goal 1: Train KL2 Scholars to apply their disciplinary expertise to translational science and equip them with the strategic thinking and management skills needed to create and sustain transformative interdisciplinary translational research programs in a rapidly changing environment. Goal 2: Provide KL2 Scholars with the skills to mentor members of their own research teams as well as the next generation of investigators. TraCS serves as a true “home” for early-stage researchers who wish to engage in shared learning, peer review and, most importantly, the development of a peer group that encourages innovation, resilience, and retention in science. Our KL2 Program provides Scholars with experiences that enable them to transcend methodologic boundaries, adopt concepts from other disciplines, and produce truly transformative translational science.