North Carolina Translational and Clinical Science Institute (NC TraCS) KL2

I.机构职业发展核心摘要 该ESTA/TraCS KL 2是旗舰计划，通过它我们塑造初级翻译的发展 科学家成为首席研究员和研究领导者。自成立以来，我们已经资助了63 学者：目前有15人获得KL 2的支持，48人完成了该计划。在这48个国家中， 一个是受资助的学术研究人员;一个是临床医生;一个在工业界担任研究职位。我们的成功 我们73%的“毕业”学者获得了大量（超过10万美元）的奖学金，这一事实证明了这一点。 在KL 2开始后的54个月内获得独立PI资助。我们的学者代表6 学校和17个部门，这种多样性不仅将KL 2与其他培训项目区分开来， 校园，但也鼓励和促进学者之间的翻译合作，谁可能不会 否则会有交集这个非常成功的计划是基于团队科学的哲学， 学科，学校和中心/研究所;致力于工作的优秀专家教师队伍 与导师和学者密切合作，作为教师发展协调团队方法的一部分;计划 领导，跟上不断变化的科学和CTSA计划的计划优先事项; 一种学院文化，我们的前学者愿意继续参与，并给予时间和专业知识 作为榜样、导师和合作者回到项目中。 展望未来，KL 2计划正在适应我们申请人群体不断变化的性质和不断发展的 通过用个性化培训取代强制性的两年制课程， 由学者与KL 2计划教师及其导师合作开发的途径。另外我们 我已经建立了KL 2校友咨询团队，KL 2毕业生在其中提供有关培训的反馈 组件和建议的新内容或重新设计如何交付当前的内容。其他变化包括 增加与CTSA联盟的合作活动，整合新的倡议，如NCATS 试验创新网络和TraCS劳动力发展计划纳入培训活动， 开展辅导活动，并引入一套科学和研究领导能力。目标1： 培训KL 2学者将他们的学科专业知识应用于转化科学，并为他们提供 创造和维持变革性跨学科所需的战略思维和管理技能 在快速变化的环境中的翻译研究计划。目标2：为KL 2学者提供 指导自己的研究团队成员以及下一代研究人员的技能。 TraCS是希望参与共享学习、同行评议和研究的早期研究人员的真正“家”。 而且，最重要的是，发展一个鼓励创新、适应力和保留的同龄人群体， 科学我们的KL 2计划为学者提供经验，使他们能够超越方法论 边界，采用其他学科的概念，并产生真正的变革性转化科学。

I. Institutional Career Development Core Abstract The UNC/TraCS KL2 is the flagship program through which we shape the development of junior translational scientists to become Principal Investigators and research leaders. Since our inception, we have funded 63 Scholars: 15 are currently supported on the KL2, and 48 have completed the Program. Of these 48, 46 are funded academic investigators; one is a clinician; and one holds a research position in industry. Our success to date is exemplified by the fact that 73% of our “graduated” Scholars have received significant (over $100,000 for a single grant) independent PI funding within 54 months of their starting the KL2. Our Scholars represent 6 Schools and 17 departments, a diversity that not only distinguishes this KL2 from other training programs on campus, but also encourages and facilitates translational collaborations among Scholars who might not otherwise cross paths. This highly successful program is grounded in a philosophy of team science across disciplines, schools, and centers/institutes; an outstanding corps of expert faculty who are committed to work closely with the mentors and Scholars as part of a coordinated team approach to faculty development; program leadership that keeps abreast of the evolving scientific and programmatic priorities of the CTSA Program; and a collegial culture in which our former Scholars willingly continue to be engaged and give time and expertise back to the program as role models, mentors, and collaborators. Going forward, the KL2 Program is adapting to the changing nature of our applicant pool and the evolving translational workforce pipeline by replacing the mandatory two-year curriculum with personalized training pathways developed by Scholars in collaboration with KL2 program faculty and their mentors. In addition, we have established the KL2 Alumni Advisory Team, in which KL2 graduates provide feedback about training components and advice on new content or redesign of how current content is delivered. Other changes include increasing collaborative activities with the CTSA Consortium, integrating new initiatives such as the NCATS Trial Innovation Network and TraCS Workforce Development Program into training activities, expanding activities in mentoring, and introducing a set of competencies in scientific and research leadership. Goal 1: Train KL2 Scholars to apply their disciplinary expertise to translational science and equip them with the strategic thinking and management skills needed to create and sustain transformative interdisciplinary translational research programs in a rapidly changing environment. Goal 2: Provide KL2 Scholars with the skills to mentor members of their own research teams as well as the next generation of investigators. TraCS serves as a true “home” for early-stage researchers who wish to engage in shared learning, peer review and, most importantly, the development of a peer group that encourages innovation, resilience, and retention in science. Our KL2 Program provides Scholars with experiences that enable them to transcend methodologic boundaries, adopt concepts from other disciplines, and produce truly transformative translational science.