Administrative Core

项目摘要/摘要：行政核心 该中心汇集了一支由生物医学、化学/燃烧工程师和物理学家组成的真正多元化的团队， 和非技术研究人员和支持人员进行跨学科研究，审查 危险物品热处理过程中形成的污染物颗粒系统对环境和健康的影响 浪费。该中心推动的科学理念和创新专注于这些环境 持久性自由基(EPFR)。我们的团队由路易斯安那州立大学(LSU)、路易斯安那州立大学(LSU) 新奥尔良健康科学中心，路易斯安那州立大学北卡罗来纳州立大学兽医学院， 加州多米尼加大学和澳大利亚昆士兰大学。所有参与的机构都有 对中心的成功进行了投资，并同意提供大量额外支持，这些支持将用于 为我们的中心提供灵活性，以快速有效地响应新的机遇，追求高 风险/高影响和变革性研究，并吸引新的教员/研究人员作为参与者。这个 管理核心(AC)将跨这些站点监控、区分优先顺序、分配和管理资源。这 包括促进有效协作、数据和信息共享、快速传播资源、 评价和管理方案执行情况，并查明和解决问题。 创新包括组织会议，以跨项目和核心向利益相关者传播信息， 利用最先进的机构资源(例如，路易斯安那州立大学高级微结构中心和 器件和材料表征实验室；LSUHSC的统计分析核心；LSUSVM的吸入 研究设施)和开发用于存档、共享的门户网站(由信息和通信技术中心和信息和通信技术中心管理 并分析该中心产生的所有数据。将研究翻译融入核心 为更好的跨中心协作和双向RT创造机会。的RT组件 核心将与研究经验和培训协调核心以及项目和核心一起工作 领导者让受训人员参与社区参与活动并提供专业发展 与环境健康科学和中心研究相关的概念讲习班。RT组件将 通过邀请以下方式建立新的和加强现有的社区、行业、政府和SRP伙伴关系 合作伙伴参加中心的活动，例如一年一度的德林格研讨会。最后，路易斯安那州立大学办公室 研究与经济发展为多学科研究创造了支持环境 我们的中心等计划提供集中的合规官员(IRB、IACUC等)，促进 /为申请组织科学审查员，并协助编辑和汇编 求婚。中心已经并将继续使用外部咨询委员会的反馈意见，即 由来自我们各个研究领域的专家以及来自社区和其他利益相关者组成，以履行 NIEHS和超级基金计划的任务授权。

Project Summary/Abstract: Administrative Core This Center brings together a truly diverse team of biomedical, chemical/combustion engineers and physicists, and non-technical researchers and support staff to conduct interdisciplinary research examining the environmental and health impacts of pollutant particle systems formed during thermal treatment of hazardous wastes. The driving scientific concept and innovation of this Center focuses on these environmentally persistent free radicals (EPFRs). Our team is comprised of experts from Louisiana State University (LSU), LSU Health Sciences Center in New Orleans, LSU School of Veterinary Medicine, North Carolina State University, Dominican University of California, and University of Queensland, Australia. All participating institutions have invested in the success of the Center and have agreed to offer significant additional support, which will be used to provide flexibility for our Center to respond quickly and effectively to new opportunities, pursue high- risk/high-impact and transformative research, and attract new faculty/researchers as participants. The Administrative Core (AC) will monitor, prioritize, allocate, and manage resources across these sites. This includes fostering efficient collaboration, data and information sharing, the rapid dissemination of resources, evaluation and management of programmatic performance, and the identification and resolution of problems. Innovations include meetings structured to disseminate information across Project and Cores to stakeholders, leveraging of state-of-the-art institutional resources (e.g., LSU’s Center for Advanced Microstructures & Devices and Materials Characterization Laboratory; LSUHSC’s Statistical Analysis Core; LSUSVM’s Inhalation Research Facility) and development of a web portal (managed by the DMAC and AC) for archiving, sharing and analysis of all data generated by the Center. The integration of Research Translation (RT) into the Core creates opportunities for even greater cross-Center collaboration and bidirectional RT. The RT component of the Core will work with the Research Experience and Training Coordination Core and Project and Core Leaders to involve trainees in community engagement activities and provide professional development workshops on concepts related to environmental health science and Center research. The RT component will establish new and strengthen existing community, industry, governmental, and SRP partnerships by inviting partners to participate in Center activities, such as the annual Dellinger Symposium. Finally, LSU’s Office of Research & Economic Development has created a supportive environment for multidisciplinary research initiatives such as our Center offering centralized officers for compliance (IRB, IACUC, etc.), facilitating /organizing scientific reviewers for the application, and assisting with the editing and compilation of this proposal. The Center has and will continue to use feedback from the External Advisory Committee, which is comprised of experts from our various research fields and from the community and other stakeholders to fulfill the missions of NIEHS and the Superfund Program Mandates.