Einstein/Rwanda/DRC Consortium for Research in HIV/HPV Malignancies

爱因斯坦/卢旺达/刚果民主共和国 HIV/HPV 恶性肿瘤研究联盟

• 批准号: 10084653
• 负责人: Kathryn M. Anastos
• 金额: $ 9.68万
• 依托单位: ALBERT EINSTEIN COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-21 至 2025-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10084653
• 关键词: AIDS related cancer; African; Blood Circulation; Communication; Communities; Country; Data; Democratic Republic of the Congo; Development; Ensure; Funding; Funding Agency; Future; Genomics; Goals; Grant; HIV; Human Papilloma Virus-Related Malignant Neoplasm; Human Papillomavirus; Individual; Institution; International; Lead; Learning; Malignant Neoplasms; Mentors; Methods; Mission; Modeling; Molecular; Peer Review; Persons; Pilot Projects; Protocols documentation; Public Health; Published Comment; Publishing; Qualitative Research; Research; Research Personnel; Research Project Grants; Resource Sharing; Resources; Rwanda; Techniques; Testing; Training; United States; Work; apprenticeship; biobank; career; career development; experience; innovation; interest; member; programs; research and development; role model; symposium

ABSTRACT In this U54, we propose to establish an HPV/HIV-Associated Malignancy Research Center (HAMRC) as a partnership of institutions and investigators in Rwanda, the Democratic Republic of Congo (DRC) and the United States (US), with an integrated, trans-disciplinary focus on HIV/HPV-associated malignancies. The HAMRC is planned to have a coordinated and integrated program of research and capacity-building (Developmental Core) in HPV-related cancers in PLWH. The aim of the Developmental Core is to develop a cadre of junior and mid- level researchers who will utilize the resources developed by the Center to catalyze research in HPV/HIV-associated malignancies in Rwanda and the Democratic Republic of Congo (DRC). This development of junior and mid-level researchers will be done through an apprenticeship model in which they are paired with an experienced investigator in the development and execution of a research protocol or a pilot project. Mentoring will be individually tailored for each trainee, building on his or her prior training, research experience, interests and research projects. In addition, a peer-reviewed pilot grants program will be utilized to stimulate development of research projects specifically in HPV/HIV associated cancers. The Developmental Core will be led by three African investigators who are all independently funded researchers, thus, providing the ESIs with role models who have navigated challenges similar to their own and strong examples to follow/learn from. In addition to the Core Directors, a team of mentors will work with the trainees in the major research projects and potential pilot projects

摘要