Core I: Biostatistics Core

项目总结/摘要 生物统计学共享资源核心（BSRC）在加强U 54研究方面发挥着关键作用 基础设施演进BSRC由具有专业知识和经验的生物统计学家领导， 在太平洋岛屿人口中成功开展癌症研究的重要性。BSRC增加了科学的严谨性 通过合理的统计建议和纳入新的方法，例如 当前项目中的驱动抽样和中期分析方案。BSRC为所有人提供支持 研究工作的定量方面，包括研究设计、数据管理、统计 编程、数据分析、结果解释和演示。指定一名主要生物统计学家 每个U 54研究项目，以便在整个研究过程中提供咨询。BSRC领导人服务 作为U 54内部咨询委员会的无表决权成员，并提供统计审查，并输入， 新的研究概念。共享资源建立健康差距研究的能力在大学 关岛和夏威夷大学癌症中心通过指导教师和学生进行定量研究， 方法，从而建立研究能力，并通过正式的研讨会。此外，BSRC将促进 通过收集关于癌症风险和癌症风险流行率以及预防因素的信息进行研究， 关岛和夏威夷将用于为研究项目提供信息，并通过创建， 技术共享资源，用于存储和共享当前和过去的U 54项目数据的平台， 证件

PROJECT SUMMARY/ABSTRACT The Biostatistics Shared Resource Core (BSRC) serves a critical role in enhancing the U54 research infrastructure. The BSRC is led by biostatisticians who have the expertise and experience to contribute substantially to successful cancer research in Pacific Island populations. The BSRC adds to the scientific rigor of U54 research through sound statistical advice and inclusion of novel approaches, such as Respondent Driven Sampling and an interim analysis scheme in current projects. The BSRC provides support for all quantitative aspects of research endeavors, including study design, data management, statistical programming, data analysis, and interpretation and presentation of results. A primary biostatistician is assigned to each U54 research project in order to provide consultation throughout the study. The BSRC Leaders serve as non-voting members of the U54 Internal Advisory Committee and provide statistical review of, and input to, new research concepts. The Shared Resource builds capacity for health disparities research at University of Guam and the University of Hawai`i Cancer Center through mentoring of faculty and students on quantitative methods, thus building research capacity, and through formal seminars. Additionally, the BSRC will facilitate research through curation of information on cancer risks and prevalence of cancer risk and protective factors in Guam and Hawai`i to be used to inform research projects and through creation, with the Information Technology Shared Resource, of a platform for storage and sharing of current and past U54 project data and documents.