Core I: Biostatistics Core

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PROJECT SUMMARY/ABSTRACT The Biostatistics Shared Resource Core (BSRC) serves a critical role in enhancing the U54 research infrastructure. The BSRC is led by biostatisticians who have the expertise and experience to contribute substantially to successful cancer research in Pacific Island populations. The BSRC adds to the scientific rigor of U54 research through sound statistical advice and inclusion of novel approaches, such as Respondent Driven Sampling and an interim analysis scheme in current projects. The BSRC provides support for all quantitative aspects of research endeavors, including study design, data management, statistical programming, data analysis, and interpretation and presentation of results. A primary biostatistician is assigned to each U54 research project in order to provide consultation throughout the study. The BSRC Leaders serve as non-voting members of the U54 Internal Advisory Committee and provide statistical review of, and input to, new research concepts. The Shared Resource builds capacity for health disparities research at University of Guam and the University of Hawai`i Cancer Center through mentoring of faculty and students on quantitative methods, thus building research capacity, and through formal seminars. Additionally, the BSRC will facilitate research through curation of information on cancer risks and prevalence of cancer risk and protective factors in Guam and Hawai`i to be used to inform research projects and through creation, with the Information Technology Shared Resource, of a platform for storage and sharing of current and past U54 project data and documents.