Clinical Research Laboratory

这个临床实验室核心将提供一个高效的集中式实验室，用于日常处理和 支持项目1和项目2的临床标本分析：核心实验室的具体职能 包括： 1.处理在临床研究(计划1)中收集的血液和液体样本，以供 项目1和2以及这个核心， 2.为项目1和项目2进行诊断血清学和病毒学检测， 3.用荧光RT-PCR检测血浆/血清标本中登革病毒RNA的水平 项目1和2，以及 4.对项目1和项目2的新鲜血液样本进行流式细胞仪分析。 核心实验室将设在武装部队病毒学系的设施内。 泰国曼谷和Kamphaeng Phet医学研究所。该署已有 在黄毒学和临床研究方面有超过40年的经验。 核心临床实验室将在泰国运作，以处理大量临床样本 在本研究计划中收集，并将为项目1和2执行常规实验室测试。这 组织为支持我们的研究的常规程序提供了一个有效的系统。

This Clinical Laboratory Core will provide an efficient centralized laboratory for routine handling and analyses of clinical specimens in support of Projects 1 and 2. The specific functions of the Core Laboratory are: 1. To process blood and fluid samples collected in the clinical studies (Project 1) for utilization in Projects 1 and 2 and this Core, 2. To perform diagnostic serologic and virologic assays for Projects 1 and 2, 3. To quantify the levels of dengue virus RNA in plasma/serum samples by fluorogenic RT-PCR for Projects 1 and 2, and 4. To perform flow cytometry analyses on fresh blood samples for Projects 1 and 2. The Core Laboratory will be located in facilities of the Department of Virology, Armed Forces Research Institute of Medical Sciences in Bangkok and Kamphaeng Phet, Thailand. The Department has over 40 years of experience in flavivirology and clinical studies. A Core Clinical Laboratory will operate in Thailand to process the large number of clinical specimens collected in this research program and will perform routine laboratory tests for Projects 1 and 2. This organization provides an efficient system for routine procedures that support our research.