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Functional Immunomics Core

功能免疫组学核心

基本信息

批准号：
10093107
负责人：
Bing Li
金额：
$ 50.39万
依托单位：
UNIVERSITY OF LOUISVILLE
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-02-01 至 2025-01-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10093107
关键词：
Applications Grants Area Biological Specimen Banks Blood Cancer Center Cancer Patient Cell Separation Cells Centers of Research Excellence Clinic Clinical Contract Services Core Facility Cytometry DNA Data Databases Development Ensure Extramural Activities Fee-for-Service Plans Flow Cytometry Freezing Funding Future Genomics Goals Human Human Resources Immune Immune system Immunofluorescence Immunologic Immunologic Monitoring Immunologics Immunooncology Immunotherapy Infrastructure Institution Investments Kentucky Location Malignant Neoplasms Molecular Mus Paraffin Embedding Patients Phase Phenotype Process Proteins Protocols documentation Publications RNA Research Research Personnel Research Support Resources Running Sampling Services Site Slide Specimen Stains Technology Tissues Training Training and Education Translations Tumor Tissue Tumor-Associated Process Universities University resources Writing cancer immunotherapy clinical application design equipment acquisition innovation instrument instrumentation interest member new therapeutic target novel operation prospective success tissue processing tissue/cell preparation transcriptomics treatment strategy tumor immunology

项目摘要

SUMMARY (Functional Immunomics Core) The primary goal of the Functional Immunomics Core (FIC) is to serve as the central infrastructure entity that supports all the investigators in the Center for Cancer Immunology and Immunotherapy (CCII) COBRE. FIC will utilize new equipment purchased with institutional funds and leverage existing facilities at the University of Louisville to provide molecular/cellular immune profiling for mouse and human projects in the CCII. Specific Aim 1 is to build a functional immunomics facility at the University of Louisville. With the support of CCII, we will establish a streamlined state-of-the-art immunomics facility in a central location by incorporating the existing resources of the University of Louisville. This unique resource will act as a vital integrative component of the CCII through providing centralized services not only for its members but also for the Institution as a whole. Specific Aim 2 is to utilize the comprehensive and integrative FIC platform to ensure the success of CCII-supported projects. The major goal of the FIC will be to support the development, progress and success of proposed CCII projects in all phases of their research. Particularly, the FIC will provide human sample analytics expertise and technical services to support the specific aims of the CCII projects. Specific Aim 3 is to facilitate translational cancer immunology/immunotherapy research and develop a self-sustaining entity of the CCII through University/region-wide services. In summary, by integrating with the existing resources at the UofL, the newly-established FIC will provide a comprehensive immunomics service center for the success of the proposed CCII projects and the translation of novel experimental discoveries to clinical applications.

功能免疫组学核心