解决慢性阻塞性肺病患者持续吸烟的心理危险因素-猫眼课题宝

解决慢性阻塞性肺病患者持续吸烟的心理危险因素

批准号：

10246382

负责人：

Amanda R Mathew

金额：

$14.81万

依托单位：

RUSH UNIVERSITY MEDICAL CENTER

依托单位国家：

美国

项目类别：

财政年份：

2018

资助国家：

美国

项目状态：

已结题

起止时间：

2018-11-01 至 2023-07-31

来源：

https://reporter.nih.gov/project-details/10246382

关键词：

Abstinence Achievement Address Affect Anhedonia Anxiety Area Behavior Therapy Behavioral Behavioral Medicine Buffers Chronic Obstructive Airway Disease Clinical Cognitive Combined Modality Therapy Data Development Diagnosis Disease Progression Distress Doctor of Philosophy Dyspnea Early treatment Elements Emotional disorder Exercise Tolerance Feedback Fostering Future Goals Health Hospitalization Hour Human Individual Intervention Interview Knowledge Laboratories Lead Measures Medical Mental Depression Mentored Patient-Oriented Research Career Development Award Mentorship Methodology Methods Morbidity - disease rate Nicotine Dependence Nurses Outcome Outcome Measure Participant Patient Self-Report Patients Persons Pharmacotherapy Phase Population Preventive Medicine Protocols documentation Provider Psychological Factors Quality of life Randomized Randomized Controlled Trials Regulation Reporting Research Research Assistant Research Priority Risk Factors Safety Sampling Scientist Series Smoke Smoker Smoking Smoking Cessation Intervention Smoking Status Stress Structure Symptoms Testing Tobacco Training Treatment Efficacy Treatment Factor Universities Work anxiety sensitivity anxiety symptoms base behavioral health career career development cigarette smoking clinical care clinically significant comorbidity depressive symptoms design effective therapy experimental study health disparity high risk improved indexing individualized medicine medical schools mindfulness mortality multi-component intervention multidisciplinary novel phase 1 designs pilot trial pleasure primary outcome professor psychologic pulmonary rehabilitation recruit respiratory response secondary outcome self help skills smoking cessation targeted treatment therapy design therapy development treatment adherence treatment as usual trial design

项目摘要

项目成果

Amanda R Mathew的其他基金

相似基金

相关文献

中文摘要

翻译

项目总结/摘要慢性阻塞性肺疾病（COPD）主要是由吸烟和吸烟引起的戒烟是减缓疾病进展的一线治疗。尽管如此，近50%的COPD患者诊断后继续吸烟。患有COPD的吸烟者报告并发症的发生率很高- 尼古丁依赖、抑郁和焦虑--这些都是戒烟的障碍。拟议的研究将制定并试点测试针对常见心理因素的行为干预措施这些并发症的基础，并促进COPD患者戒烟。拟议研究的主要目的是：1）通过以下方式完善行为治疗成分：与患者和提供者的定性访谈，2）制定量身定制的行为治疗，以解决采用单病例设计实验，对COPD患者的心理危险因素进行研究; 3）进行试点随机对照试验（RCT），以检查多组分干预对吸烟的影响结果，与最低限度增强的常规护理相比。拟议的项目将是第一个适应行为治疗，专门针对吸烟的COPD患者的心理危险因素。通过针对核心的心理风险因素，行为治疗可能有助于缓冲相关的压力，随着疾病的进展，增加COPD患者的运动耐量，康复和生活质量。因此，这种干预措施有可能使大量的健康减轻COPD患者的负担，并最终降低与COPD相关的发病率和死亡率。阿曼达马修，博士，研究助理教授在西北大学范伯格学院医学，正在寻求通过K23指导的以患者为导向的研究生涯五年的支持发展奖，用于与戒烟开发和测试相关的培训和研究针对COPD患者的心理危险因素进行干预。马修博士的职业生涯目的是阐明心理因素影响吸烟的机制，对患有医学和精神共病的吸烟者进行干预，并减少烟草相关的健康差距。通过拟议的培训计划，马修博士将扩大她的知识和技能，干预开发;行为RCT设计、实施和分析;戒烟和针对COPD患者的治疗需求。马修博士的多学科导师团队在这些内容领域表现出专业知识，并致力于马修博士的职业发展。博士马修提出的工作也与行为医学研究的优先事项保持一致，西北大学范伯格医学院预防医学系。

英文摘要

PROJECT SUMMARY/ABSTRACT Chronic Obstructive Pulmonary Disease (COPD) is caused primarily by smoking and smoking cessation is the first-line treatment for slowing disease progression. Despite this, nearly 50% of COPD patients continue to smoke following diagnosis. Smokers with COPD report high rates of co-occurring conditions – nicotine dependence, depression, and anxiety – which serve as barriers to quitting. The proposed research will develop and pilot test a behavioral intervention designed to target the common psychological factors underlying these co-occurring conditions and foster smoking cessation among COPD patients. Primary aims of the proposed research are to: 1) Refine behavioral treatment components through qualitative interviews with patients and providers, 2) Develop a tailored behavioral treatment to address psychological risk factors among COPD patients using single case design experiments, and 3) Conduct a pilot randomized controlled trial (RCT) to examine the effects of the multi-component intervention on smoking outcome, as compared to minimally-enhanced usual care. The proposed project will be the first to adapt a behavioral treatment to specifically target psychological risk factors among COPD patients who smoke. By addressing core psychological risk factors, the behavioral treatment may help buffer against stress associated with disease progression and increase COPD patients' exercise tolerance, engagement in pulmonary rehabilitation, and quality of life. Thus, this intervention has potential to obviate a large number of health burdens among COPD patients, and ultimately to reduce morbidity and mortality associated with COPD. Amanda Mathew, PhD, a Research Assistant Professor at Northwestern University Feinberg School of Medicine, is seeking five years of support through the K23 Mentored Patient-Oriented Research Career Development Award for training and research related to development and testing of smoking cessation interventions targeted to psychological risk factors among COPD patients. Dr. Mathew's overarching career goals are to elucidate the mechanisms by which psychological factors impact cigarette smoking, develop novel interventions for smokers with medical and psychiatric comorbidities, and reduce tobacco-related health disparities. Through the proposed training plan, Dr. Mathew will expand her knowledge and skills related to intervention development; behavioral RCT design, conduct, and analysis; and smoking cessation and treatment needs specific to individuals with COPD. Dr. Mathew's multidisciplinary mentorship team has demonstrated expertise in these content areas, and is committed to Dr. Mathew's career development. Dr. Mathew's proposed work is also well-aligned with behavioral medicine research priorities within the Department of Preventive Medicine at Northwestern University Feinberg School of Medicine.

期刊论文(6)

专著(0)

科研奖励(0)

会议论文