Instrument Shop Module

摘要/摘要-仪器车间模块 仪器商店模块通过与以下机构密切合作显著增强了研究环境 来自视觉研究不同科学领域的研究人员，以设计和构建独特的、非 商业上可用的，成功完成NEI支持所需的仪器和设备 研究项目。该模块在设计和建造专门仪器和 设备还有助于促进高素质调查人员准备成为 NEI助学金上的PIS。此外，仪器维修模块还提供使用的仪器维修服务 由愿景研究核心的许多参与者提供，并用于将NEI资助的愿景的干扰降至最低 研究。最后，该模块为功能评估模块和 形态和成像模块，允许这些模块满足研究人员的特定需求。这个 仪表店模块位于763平方米。英国《金融时报》在W.K.凯洛格眼科中心的专用空间，是 配备夏普数控(Computer Numerical Control)车床、桥口数控铣床、金属 垂直带锯，Tennsmith方形剪刀，Tennsmith手刹，以及Zortrax M200 3D 打印机。为了帮助仪器设计和提高制造过程的效率，该模块利用 SolidWorks CAD系统。该模块的全职仪器制造商设计和制造机械 微操作器、平移工作台、加热系统、显微镜适配器、光等仪器 来源和受环境控制的动物收容箱。此外，许多独特的专业 物品是用有机玻璃制作的(例如，斑马鱼和鼠标定位装置和灌注物 用于进行电生理记录和成像的室)。在上一个资助期内， 仪器商店模块被6名参与调查人员广泛使用，另有4名调查人员使用情况一般 用户。在下一个资助期，9名参与调查人员预计将使用该模块进行适度或 广泛的学位。

SUMMARY/ABSTRACT - Instrument Shop Module The Instrument Shop Module significantly enhances the research environment by working closely with investigators from disparate scientific areas of vision research to design and construct unique, non- commercially available, instruments and devices that are required to successfully complete NEI-supported research projects. The Module's expertise in the design and construction of specialized instruments and devices also serves to facilitate the research programs of highly qualified investigators preparing to become PIs on NEI grants. In addition, the Instrument Shop Module provides an instrument repair service that is used by many participants of the Vision Research Core and serves to minimize disruptions in NEI-funded vision research. Finally, the Module constructs unique devices for the Functional Assessment Module and the Morphology and Imaging Module, which allows these Modules to meet the specific needs of investigators. The Instrument Shop Module is housed in 763 sq. ft. of dedicated space in the W.K. Kellogg Eye Center and is equipped with a Sharp CNC (computer numerical control) lathe, a Bridgeport CNC milling machine, a metal vertical band saw, a Tennsmith squaring shear, a Tennsmith hand brake, and access to a Zortrax M200 3D printer. To aid in instrument design and to increase efficiency in fabrication processes, the Module utilizes the SolidWorks CAD system. The Module's full-time Instrument Maker designs and fabricates mechanical instruments such as micromanipulators, translation stages, heating systems, microscope adapters, light sources and environmentally-controlled animal housing boxes. In addition, numerous uniquely specialized items are created with Plexiglas (for example, zebrafish and mouse positioning devices and perfusion chambers for performing electrophysiological recordings and imaging). During the prior funding period, the Instrument Shop Module was extensively utilized by 6 participating investigators with another 4 being moderate users. In the next funding period, 9 participating investigators anticipate using the Module to a moderate or extensive degree.