Developmental Research Program

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PROJECT SUMMARY The overall goal of the NYU Cancer Health Disparity (CHD) SPORE Developmental Research Program (DRP) is to stimulate novel translational research to reduce orodigestive (ODT) cancer disparities among minority and low-income populations. The aims of the NYU CHD SPORE DRP are to: 1) provide funds for promising research in cancer health disparities in orodigestive cancers as it relates to the interplay of the microbiome and immune response; 2) seek to support the development of “high-risk, high-reward” investigations in ODT cancers; 3) attract investigators with novel approaches to solving issues that contribute to cancer health disparity in orodigestive cancers; and 4) monitor the progress of developmental research projects. This program will promote the exploration of innovative ideas in translational ODT cancer disparities research by funding pilot projects proposed by investigators at the Assistant Professor level or higher. The DRP will provide guidance, advice, evaluation, and funding for 5–7 pilot projects. Specifically, the DRP will support at least 2 pilot projects per year, each for a 12-month period, with the option of a competitive renewal for another 12 months. The goal for each pilot project is to generate sufficient high-quality data to advance investigation of ODT cancers to the extent that it will enable submission of a compelling independent project to the NIH or other federal agency for funding. We will encourage DRP projects that link to an ongoing NYU CHD SPORE project. The co-Directors of the DRP are Dr. George Miller and Dr. Chau Trinh-Shevrin. Dr. Miller is Professor of Surgery and Cell Biology and leader of the Perlmutter Comprehensive Cancer Center (PCC) Tumor Immunology Program. Dr. Chau Trinh-Shevrin is Associate Professor of Population Health and Associate Director for Community Outreach and Engagement in the PCC.