Female Reproductive Tissue Mapping Center Data Analysis Core
女性生殖组织图谱中心数据分析核心
基本信息
- 批准号:10268241
- 负责人:
- 金额:$ 16.89万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-09-25 至 2022-08-31
- 项目状态:已结题
- 来源:
- 关键词:3-DimensionalAdoptedAnatomyAtlasesCell CommunicationCellsClinicalCollaborationsDataData AnalysesEmerging TechnologiesEnsureExtracellular MatrixFAIR principlesFemaleFundingHuman BioMolecular Atlas ProgramHuman bodyImageIndividualMammalian OviductsMapsMetadataModalityMolecularOrganOvaryPathologicPlacentaPoliciesProceduresQuality ControlSignal TransductionSoftware ToolsStructureSystems BiologyTechniquesTissuesUnited States National Institutes of HealthUterusVisualizationanalysis pipelinecollaboratorycomputerized data processingdata analysis pipelinedata exchangedata formatdata qualitydata standardsflexibilityinteroperabilitymetadata standardsmultiscale dataprogramsreproductivesecondary analysistool
项目摘要
SUMMARY
The Data Analysis Core (DAC) of the proposed HuBMAP Female Reproductive Tissue Mapping Center (FR
TMC) will build 3D tissue maps from data generated by the two Organ Specific Projects (OSP1: Placenta; OSP2:
Uterus, Ovary, Fallopian Tube). The DAC will collaborate with the HuBMAP Integration, Visualization &
Engagement Collaboratory (HIVE) to build an atlas of 3D tissue maps in the context of the whole human body.
The DAC will be responsible for data processing, annotation, metadata curation, analysis, and map construction
within the FR TMC. The DAC will interact closely with the OSPs within the FR TMC and will coordinate close
interactions with the other HuBMAP TMCs, HIVE and NIH Program staff. The DAC will ensure that data,
metadata, software and tools will be open, findable, accessible, interoperable, reusable (FAIR) and will maintain
flexibility to adapt processing and analysis capabilities to emerging technologies within the HuBMAP Consortium.
The DAC will assemble a FR TMC Data Release Team comprised of experts in each of the included data
modalities that will interface directly with the HIVE to ensure data quality control, metadata standards and
facilitate data transfer. The DAC will collaborate closely with the HIVE to optimize secondary analysis pipelines
and to implement the Registration User Interface to register tissue sections to reference organs and a Common
Coordinate Framework to fully integrate spatial and molecular data across individuals. As the HIVE and several
of the other TMCs were funded in 2018, we will adopt Consortium-established metadata standards, data quality
metrics, analysis techniques and data structures, with some adjustments to account for the specific tissues and
data types that are unique to the FR TMC.
总结
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Kathleen Marie Fisch其他文献
Kathleen Marie Fisch的其他文献
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{{ truncateString('Kathleen Marie Fisch', 18)}}的其他基金
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10701367 - 财政年份:2022
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$ 16.89万 - 项目类别:
Female Reproductive Tissue Mapping Center Data Analysis Core
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$ 16.89万 - 项目类别:
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Omics Data Generation Center (ODGC) for the Acute to Chronic Pain Signatures (A2CPS) Program
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10224832 - 财政年份:2019
- 资助金额:
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Omics Data Generation Center (ODGC) for the Acute to Chronic Pain Signatures (A2CPS) Program
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Omics Data Generation Center (ODGC) for the Acute to Chronic Pain Signatures (A2CPS) Program
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10415817 - 财政年份:2019
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