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Non-mutational phenotypic evolution in metastatic melanoma: the role of the epidermal growth factor receptor and epithelial-mesenchymal transition-like processes in treatment resistance.

Non-mutational phenotypic evolution in metastatic melanoma: the role of the epidermal growth factor receptor and epithelial-mesenchymal transition-like processes in treatment resistance.
转移性黑色素瘤的非突变表型进化：表皮生长因子受体和上皮间质转化样过程在治疗抵抗中的作用。
批准号：
nhmrc : 1055456
负责人：
Dr Miles Andrews
金额：
$9.4万
依托单位：
La Trobe University
依托单位国家：
澳大利亚
项目类别：
Postgraduate Scholarships
财政年份：
2013
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2013-01-01 至 2016-12-31
来源：
https://researchdata.edu.au/non-mutational-phenotypic-treatment-resistance/112467
关键词：
Nonmutationalphenotypicevolutionmetastatic

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中文摘要
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英文摘要
Phenotypic change has been identified in multiple settings relating to melanoma progression and metastasis. We have identified a degree of overlap between features of phenotypic plasticity, epithelial-to-mesenchymal transition, and the emergence of treatment resistance. This project will further examine mechanisms underlying these changes, focusing on the role of the epidermal growth factor.
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会议论文
Deriving actionable strategies to enhance cancer immunotherapy response
  • 批准号：
    nhmrc : 1148680
  • 项目类别：
    Early Career Fellowships
  • 资助金额：
    $29.82万
  • 财政年份：
    2018
  • 负责人：
    Dr Miles Andrews
  • 依托单位：
    La Trobe University
Deriving actionable strategies to enhance cancer immunotherapy response
  • 批准号：
    nhmrc : GNT1148680
  • 项目类别：
    Early Career Fellowships
  • 资助金额：
    $43.88万
  • 财政年份：
    2018
  • 负责人：
    Dr Miles Andrews
  • 依托单位：
    La Trobe University
Characterisation of the role of mesenchymal phenotypes and EGFR in treatment-resistant melanoma.
  • 批准号：
    nhmrc : GNT1055456
  • 项目类别：
    Postgraduate Scholarships
  • 资助金额：
    $11.32万
  • 财政年份：
    2013
  • 负责人：
    Dr Miles Andrews
  • 依托单位：
    La Trobe University
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