SPeCTRE 2.0: The Sunflower Pediatric Clinical Trials Research Extension

Spectre 2.0：向日葵儿科临床试验研究扩展

• 批准号: 10240731
• 负责人: Ann M Davis
• 金额: $ 41.29万
• 依托单位: UNIVERSITY OF KANSAS MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-23 至 2025-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10240731
• 关键词: Address; Advisory Committees; Affect; Area; Area Health Education Centers; Cancer Center; Child; Child Health; Childhood; Clinical Skills; Clinical Trials; Clinical Trials Network; Clinical and Translational Science Awards; Collaborations; Communities; Computerized Medical Record; Conduct Clinical Trials; Contracts; Development Plans; Educational Curriculum; Educational Status; Effectiveness; Ethnic group; Exposure to; Family; Funding; Future; Geography; Goals; Health; Health Services Accessibility; Healthcare; Hispanics; Immunization; Income; Infant Mortality; Infrastructure; Institutional Review Boards; Kansas; Lead; Medical; Mentors; Multi-Institutional Clinical Trial; Not Hispanic or Latino; Obesity; Outcome; Outcome Measure; Patient Recruitments; Patients; Pediatric Research; Performance; Policies; Population; Prevention Research; Provider; Quality of life; Registries; Reporting; Research; Research Personnel; Resources; Risk Behaviors; Rural; Rural Community; Rural Health; Site; Specialist; Sunflowers; Telemedicine; Time; Training; United States National Institutes of Health; Universities; Vaccines; Variant; Work; clinical research site; demographics; education research; ethnic minority population; experience; frontier; health care availability; implementation science; improved; low socioeconomic status; outreach; pediatric patients; programs; racial and ethnic; recruit; rural America; rural Hispanic; rural area; rural disparities; rural families; rural underserved; skill acquisition; skills; social health determinants; suburb; success; telehealth; treatment research; underserved area; underserved community

Project Summary/Abstract Children living in rural and underserved communities experience poorer health and worse health outcomes than children living in other areas. Our state, Kansas, exemplifies this problem, with rural children having lower immunization rates, higher infant mortality rates, and higher rates of obesity than their urban and suburban counterparts. Also, children and families from rural and underserved areas are much less likely to participate in clinical trials, which could study these and other health conditions and ultimately lead to improvement in health for these rural and underserved children and families. The purpose of the current application is to propose that the state of Kansas, a largely rural state, renew its status as a Clinical Site of the Child Health Outcomes (ECHO) IDeA States Pediatric Clinical Trials Network (ISPCTN). Our goals with this application are: 1) to assure that rural and underserved children in Kansas participate in multicenter clinical trials research, and 2) to improve the infrastructure for pediatric clinical trials in our state. The current application, Sunflower Pediatric Clinical Trials Research Extension (SPeCTRE 2.0), has three primary aims focused on improving research capacity through professional skills development of clinicians and researchers in our state, expanding clinical trials to rural and underserved children in our state, and evaluating and improving the effectiveness and efficiency of clinical trials in the network. We propose a strong administrative team and detailed administrative plan to support this work and have an extensive network throughout our state to support our activities as planned. Our site was very productive during the initial funding cycle and will expand on these activities during SPeCTRE 2.0. We propose a very strong Clinical Skills Development Plan focused on implementation science and individualized training plans that capitalizes upon our strong existing campus resources and our Clinical and Translational Science Award (CTSA) in Kansas called Frontiers. As noted in our Rural Engagement Plan, we plan to engage both communities and providers through our Primary Clinical Sites and our Stakeholder Advisory Committee Sites. We also note that Kansas is a highly rural state with a high volume of pediatric patients who are rural and underserved who we will bring to the network. Finally, our application includes a Clinical Trial Proposal of the CoVER (The Collaboration for Vaccine Education and Research) curriculum, which is a trial that may be considered by the network for potential future dissemination. The results of the current work could lead to improvement in the health of rural and underserved children in the state of Kansas and improvements in the infrastructure in our IDeA state to support future pediatric clinical trials.

项目总结/摘要 生活在农村和服务不足社区的儿童健康状况较差，健康结果更差 生活在其他地区的孩子。我们的州，堪萨斯，就证明了这一问题，农村儿童的 免疫率，婴儿死亡率较高，肥胖率高于城市和郊区 同行此外，来自农村和服务水平低下地区的儿童和家庭参与社区教育的可能性要小得多。 临床试验，可以研究这些和其他健康状况，并最终导致健康状况的改善 为这些农村和缺乏服务的儿童和家庭。本申请的目的是提出， 堪萨斯州是一个大部分是农村的州，更新了其作为儿童健康结果临床研究中心的地位 IDEA美国儿科临床试验网络（ISPCTN）。我们的目标与此应用程序是：1） 确保堪萨斯的农村和服务不足的儿童参加多中心临床试验研究，2） 改善我们州儿科临床试验的基础设施。当前应用程序，向日葵儿科 临床试验研究扩展（SPeCTRE 2.0）有三个主要目标，重点是改善研究 通过我们国家临床医生和研究人员的专业技能发展能力，扩大临床 对我们州农村和服务不足的儿童进行试验，评估和提高有效性， 网络中临床试验的效率。我们建议一个强大的行政团队和详细的行政 我计划支持这项工作，并在全州范围内建立广泛的网络，以支持我们的活动， 计划好了我们的网站在最初的融资周期中非常富有成效，并将在2015年期间扩大这些活动。 SPeCTRE 2.0.我们提出了一个非常强大的临床技能发展计划，重点是实施科学 和个性化的培训计划，利用我们强大的现有校园资源和我们的临床 和堪萨斯的翻译科学奖（CTSA），名为Frontiers。正如我们的农村参与计划所指出的， 我们计划通过我们的主要临床站点和我们的利益相关者， 咨询委员会网站我们还注意到，堪萨斯是一个高度农村化的州， 我们将把农村和服务不足的患者带到网络中。最后，我们的应用程序包括一个 CoVER（疫苗教育与研究合作组织）课程的临床试验提案， 这是网络可以考虑用于潜在的未来传播的试验。的结果 目前的工作可能会改善堪萨斯州农村和服务不足儿童的健康状况 以及改善我们IDEA州的基础设施，以支持未来的儿科临床试验。