Research Education Component Rio Grande Valley AD-RCMAR

项目摘要--研究教育部分 由于阿尔茨海默病(AD)和S病(AD)而造成的痛苦、残疾和生命损失的巨大负担 相关情况代表着一场全球危机。事实上，阿尔茨海默病和相关疾病(ADRD)构成了第二个 高收入国家多年来的主要残疾原因--833万人，占残疾人数的近1/10 各种原因造成的。这些事实激励和推动了研究，促进了预防和治疗的创造力和创新 广告，特别是在少数群体，特别是西班牙裔美国人，他们受到了不成比例的影响。 少数民族学者在科学研究中的代表性不足，特别是在ADRD 研究的重点是AD对拉美裔美国人影响过高的原因和可能的补救措施。这个 拟议AD的主要目标--大学少数民族老龄化研究中心(AD-RCMAR 得克萨斯州里奥格兰德山谷(UTRGV)的目标是发现、培训和指导一批不同的杰出人才和 代表不足的群体中的妇女，她们将成为社会和行为科学进步的领导者 可翻译为改善AD及相关疾病(ADRD)影响的研究，特别是在衰老方面 拉美裔和其他少数民族。为了实现这一目标，AD的研究教育部分(REC)- UTRGV的RCMAR将利用经验丰富、成功的 这些领域的跨学科调查员和领导者，以实现以下具体目标：(1)支持 创新、高影响力的多学科试点项目，成功申请校外 美国国立卫生研究院支持少数民族科学家的创新研究和进一步的职业发展 ADRD研究(例如，R和K奖)；(2)确定、参与和提供高质量的培训和 为代表不足的少数群体的优秀教师提供个性化的职业发展支持 专注于ADRD研究和翻译，以改善少数民族的健康；(3)开发和培训AD-RCMAR 拥有专门研究技能和知识的科学家将需要成为独立的研究人员 致力于少数群体中的AD。为了实现这些目标，我们建立了一支领导团队， 在研究教育、指导计划和评估以及领导方面有丰富的经验 旨在改善少数民族和拉美裔美国人健康的跨学科协作研究 我们已经考虑到了所有需要的行政和后勤支助。实习生 学员将参与开发协作研究并从丰富的身临其境体验中获益 解决贫困人口(主要是西班牙裔)中社会和生物行为ADRD的贡献者和影响 美国-墨西哥边境地区的RGV。他们的培训和努力的部分目的是在现有的基础上再接再厉 与UTRGV和UTRGV有广泛联系的社区医疗和社会支持网络和资源 其AD-RCMAR的领导团队。建议的区域经济走廊将提供一个有效和具成本效益的架构， UTRGV AD-RCMAR将吸引和支持一个跨机构的教育和研究企业，该企业将 推进减少ADRD健康差距的目标。

Project Summary - Research Education Component The overwhelming burden of suffering, disability, and years of life lost due to Alzheimer´s disease (AD) and related conditions represent a global crisis. Indeed, AD and related disorders (ADRD) constitute the second leading cause of years lived with disability (YLDs) in high income countries – 8.33 million, nearly 1/10 of YTD from all causes. These facts inspire and drive research and foster creativity and innovation to prevent and cure AD, particularly among minority groups and especially Hispanics, that are disproportionally affected by it. Scholars from ethnic minority groups are underrepresented in scientific research, particularly in ADRD research focused on the causes and potential remedies of the unduly high impacts of AD on Hispanics. The primary goal of the proposed AD-Research Center for Minority Aging Research (AD-RCMAR) at the University of Texas Rio Grande Valley (UTRGV) is to identify, train and mentor a diverse group of outstanding men and women of underrepresented groups who will become leaders of scientific advances in social and behavioral research that is translatable to ameliorating impacts of AD and related disorders (ADRD), particularly in aging Hispanics and other minorities. To accomplish this goal, the Research Education Component (REC) of the AD- RCMAR at UTRGV will leverage the research expertise and resources of experienced, successful, interdisciplinary investigators and leaders in these fields to achieve the following specific aims: (1) support innovative, high-impact multidisciplinary pilot projects that lead to successful applications for extramural support by NIH of innovative research and further career development for scientists in minorities-focused ADRD research (e.g., R and K awards); (2) identify, engage, and provide high-quality training and individualized career development support to outstanding faculty of underrepresented minority groups who are focused on ADRD research and translation to improve minorities' health; (3) develop and train AD-RCMAR Scientists in research-specific skills and knowledge they will need to become independent researchers dedicated to AD in minority populations. To accomplish these goals, we have built a leadership team with extensive experience in research education, planning and evaluation of mentoring, and leadership of collaborative interdisciplinary research efforts aimed at improving minorities' and Hispanics' health in targeted geographic populations, and we have accounted for all needed administrative and logistic support. Trainees and mentees will engage in and benefit from a rich immersive experience in developing collaborative research addressing social and bio-behavioral ADRD contributors and impacts in the poverty-stricken, primarily Hispanic US-Mexico border region of the RGV. Their training and efforts will be aimed in part at building upon existing community healthcare and social support networks and resources that have extensive links to UTRGV and the leadership team of its AD-RCMAR. The proposed REC will provide an effective and cost-efficient structure for the UTRGV AD-RCMAR to attract and support a cross-institution education and research enterprise that will advance the goals reducing health disparities for ADRD.