Developmental Research Program

发展研究计划

• 批准号: 10251137
• 负责人: MARK A. MC NIVEN
• 金额: $ 7.31万
• 依托单位: MAYO CLINIC ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-10 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10251137
• 关键词: Advisory Committees; Award; Clinic; Clinical; Clinical Research; Data; Development; Disabled Persons; Ensure; Evaluation; Funding; Future; Generations; Goals; Hepatobiliary; Laboratories; Leadership; Minority; Monitor; Morbidity - disease rate; Patients; Peer Review; Population; Population Sciences; Process; Program Research Project Grants; Research; Research Personnel; Research Project Grants; Resources; Secure; Translating; Translational Research; Woman; Work; anticancer research; base; experience; hepatobiliary cancer; high risk; innovation; mortality; originality; programs; recruit

DEVELOPMENTAL RESEARCH PROGRAM – PROJECT SUMMARY The goal of the Mayo Clinic HBCs SPORE Developmental Research Program (DRP) is to attract, develop, support, and monitor the most promising and innovative projects pertaining to translational hepatobiliary cancer research. Each year the DRP will provide three, one-year awards of $50,000 each with the possibility of an additional year of support based upon the demonstration of significant progress and potential. A rigorous peer- review process utilizing the expertise of the Internal Scientific Advisory Committee and other experienced investigators will evaluate all applications based upon the following criteria: scientific merit, originality, qualifications of the applicant/co-investigator(s), and translational potential. While the translational trajectory of all applications needs to be readily apparent, we encourage high risk/high payoff proposals investigating all aspects pertaining to the morbidity and mortality of hepatobiliary cancer from the bench to the population. This will be accomplished through the following Specific Aims: (1) Solicit and support innovative and interdisciplinary translationally-relevant laboratory, population science, and clinical studies in hepatobiliary cancer; (2) Encourage the recruitment of qualified minorities, women, and persons with disabilities; (3) Provide critical evaluation of all DRP applications and awardee progress; and (4) Facilitate the development of DRP funded proposals into R01-level applications and/or future HBCs SPORE projects. It is expected that developmental research project support will result in the generation of data that will serve as the basis for additional HBCs SPORE-sponsored projects or support through other external peer-reviewed mechanisms. The HBCs SPORE leadership will work with the investigators to help secure independent R01-level funding. One-page outlines of three potential research projects are included to demonstrate the depth and breadth of ongoing research that can be eligible for funding through the HBCs SPORE Developmental Research Program.

发展研究计划——项目摘要 梅奥诊所 HBC SPORE 发展研究计划 (DRP) 的目标是吸引、开发、 支持并监测与转化性肝胆癌相关的最有前途和创新的项目 研究。每年 DRP 将提供三项为期一年的奖励，每项奖励 50,000 美元，并有可能获得 根据显着进展和潜力的表现，提供额外一年的支持。严谨的同行 利用内部科学咨询委员会和其他经验丰富的专家的专业知识进行审查过程 研究人员将根据以下标准评估所有申请：科学价值、原创性、 申请人/共同研究者的资格以及转化潜力。虽然平移轨迹 所有应用都需要显而易见，我们鼓励高风险/高回报的建议调查所有 从实验室到人群的肝胆癌发病率和死亡率的相关方面。这 将通过以下具体目标来实现：（1）征求和支持创新和 跨学科翻译相关实验室、人口科学和肝胆临床研究 癌症; （二）鼓励录用合格的少数民族、妇女、残疾人； (3) 提供 对所有 DRP 申请和获奖者进展进行严格评估； (4) 促进DRP的发展 资助 R01 级应用程序和/或未来 HBC SPORE 项目的提案。预计 发展研究项目的支持将产生数据，作为研究的基础 其他 HBC SPORE 赞助的项目或通过其他外部同行评审机制提供的支持。 HBC 的 SPORE 领导层将与调查人员合作，帮助确保独立的 R01 级资金。 其中包括三个潜在研究项目的一页大纲，以展示研究的深度和广度 正在进行的研究有资格通过 HBC SPORE 发展研究获得资助 程序。