P & F Sorscher
磷
基本信息
- 批准号:10260488
- 负责人:
- 金额:$ 8.57万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-09-10 至 2023-07-31
- 项目状态:已结题
- 来源:
- 关键词:AddressAnimal ModelApoptosisAreaAwardBiomedical EngineeringBiomedical ResearchCatchment AreaCell Death Signaling ProcessCenter Core GrantsChild health careClinicalClinical ResearchCollaborationsCystic FibrosisDiabetes MellitusDiseaseDistalElementsEndocrineEndowmentEngineeringEnvironmentEventFacultyFeasibility StudiesFoundationsFundingFunding AgencyFutureGrantGuidelinesIleusInflammatoryInfrastructureInstitutesInstitutionInterdisciplinary StudyInterventionIntestinal ObstructionLettersManuscriptsMeconiumMethodologyNational Institute of Diabetes and Digestive and Kidney DiseasesNutritionalObstructionOutcomePathogenesisPathway interactionsPhenotypePilot ProjectsPrivatizationProcessProductivityRecommendationResearchResearch DesignResearch PersonnelResearch PriorityResearch SupportResourcesRoleScienceSourceSpecific qualifier valueStudy SectionSyndromeTeacher Professional DevelopmentTechnologyTranslational ResearchTranslationsUnited States National Institutes of HealthUniversitiesbasecareercystic fibrosis related diabetesdesigndiabetes pathogenesisgastrointestinalhigh riskinflammatory disease of the intestineinnovationintestinal injurymetabolomicsmultidisciplinarynovelprofiles in patientsprogramsranpirnaserecruitrespiratorysmall molecule
项目摘要
Pilot and feasibility projects within the P30 Center will contribute to multidisciplinary research at Emory and
affiliated institutions, enhance faculty development, extensively utilize scientific cores, and integrate well with
the global research themes of our cystic fibrosis (CF) research program. A strong commitment to basic and
translational aspects of CF science (and NIDDK-relevant sequelae of the disease in particular), together with
substantial institutional support, momentum, and innovation, are described by this proposal. Infrastructure and
methodologies for solicitation, review, and advancement of pilot projects are in place, and have been
successfully utilized at Emory for many years. The P30 Pilot and Feasibility component will serve as a key
element within an intellectual environment for cystic fibrosis research that is well-established and growing
rapidly. Specific Aims of the Pilot and Feasibility component are as follows:
Specific Aim 1. Provide research support that will enable eligible investigators to explore the feasibility
of innovative, high-risk concepts directed towards CF basic biomedical, clinical, and translational
research. Projects typically last two years, are concordant with the overall objectives of the P30, and are
expected to result in further grant support from NIH or other funding agencies.
Specific Aim 2. Provide an administrative framework for oversight and review of Pilot and Feasibility
studies. This includes recommendations regarding continuation (or termination) of pilots to the P30 Program
Steering Committee, solicitation and review of pilot applications, record-keeping with regard to grant and
manuscript productivity of pilot investigators, tracking subsequent career events of awardees, and all aspects
of program management.
Two Pilot and Feasibility projects are recommended for NIH funding based on study section-type review
and prioritization as described in the submission. Research summaries are provided for Project 1 (“Role of
Programmed Cell Death (PCD) Signaling in Inflammatory Intestinal Injury”) and Project 2 (“Deep Phenotyping
of Cystic Fibrosis-Related Diabetes Integrating Small Molecule -Omics and Clinical Outcomes”). Support
through the NIH P30 mechanism will advance novel findings relevant to NIDDK-prioritized aspects of CF
pathogenesis and treatment. Pilot and Feasibility projects will engage a long-standing passion among our
faculty to develop novel and better therapies for cystic fibrosis, and furnish an engine to drive innovation.
P30中心内的试点和可行性项目将为埃默里大学和埃默里大学的多学科研究做出贡献
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Eric J SORSCHER其他文献
Eric J SORSCHER的其他文献
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{{ truncateString('Eric J SORSCHER', 18)}}的其他基金
Intratumoral generation of F-Ade to ablate low growth fraction HNSCC
瘤内生成 F-Ade 以消除低生长分数 HNSCC
- 批准号:
9311681 - 财政年份:2017
- 资助金额:
$ 8.57万 - 项目类别:
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