Rheumatic and Autoimmune Diseases in Minority Communities

少数民族社区的风湿病和自身免疫性疾病

• 批准号: 10265854
• 负责人: Michael Ward
• 金额: $ 37.37万
• 依托单位: NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10265854
• 关键词: Area; Arthritis; Assessment tool; Autoimmune Diseases; Clinical; Complementary and alternative medicine; District of Columbia; Evaluation; Goals; Immune; Individual; Informed Consent; Intervention; Methods; Minority; Musculoskeletal; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Neighborhood Health Center; Outcome; Outcome Assessment; Patient Self-Report; Patients; Process; Research; Research Personnel; Research Support; Rheumatism; Rheumatoid Arthritis; Serological; Standardization; Symptoms; Systemic Lupus Erythematosus; Washington; Yoga; barrier to care; care providers; cohort; disease phenotype; ethnic difference; ethnic minority population; experience; health disparity; improved; metropolitan; minority communities; standard of care

This project studies the clinical presentation of rheumatic diseases in an underserved, largely ethnic minority community in the Washington, DC metropolitan area. Through the NIAMS Community Health Center, subjects with rheumatic complaints are evaluated and provide clinicians with first-hand experience in understanding ethnic differences in autoimmune disease phenotypes as well as barriers to care. This project has supported research on cultural differences in understanding standardized self-report outcome assessment tools, determination of clinically important improvements in rheumatoid arthritis, use of complementary and alternative medicine in patients with rheumatic symptoms, acceptability of yoga as a treatment for arthritis by minority individuals, and understanding of the research process and informed consent among ethnic minorities. In addition, researchers have examined interventions to improve the referral process between primary care providers and subspecialists. Serological studies are currently underway to examine immune abnormalities in patients with rheumatoid arthritis and systemic lupus erythematosus.

该项目研究了华盛顿特区大都市区服务不足的主要少数民族社区风湿病的临床表现。通过NIAMS社区卫生中心，对风湿病患者进行评估，并为临床医生提供第一手经验，了解自身免疫性疾病表型的种族差异以及护理障碍。该项目支持文化差异研究，以理解标准化自我报告结果评估工具，确定类风湿关节炎的临床重要改善，在风湿性症状患者中使用补充和替代医学，少数民族个体对瑜伽作为关节炎治疗的可接受性，以及了解研究过程和少数民族的知情同意。此外，研究人员还研究了干预措施，以改善初级保健提供者和专科医生之间的转诊过程。目前正在进行血清学研究，以检查类风湿关节炎和系统性红斑狼疮患者的免疫异常。