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Imaging & Spectroscopy Core

影像学

基本信息

批准号：
10090746
负责人：
Narasimhan Rajaram
金额：
$ 14.27万
依托单位：
UNIVERSITY OF ARKANSAS AT FAYETTEVILLE
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-04-01 至 2026-02-28
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10090746
关键词：
Aging Applications Grants Arkansas Award Bioenergetics Biological Models Biology Biomedical Research Cell physiology Cells Cellular Metabolic Process Centers of Research Excellence Collaborations Communities Consultations Data Analyses Data Science Data Science Core Disease Experimental Designs Fostering Foundations Functional disorder Funding Future Goals Grant Image Image Analysis Imaging Techniques Imaging technology Label Light Malignant Neoplasms Medicine Metabolic Metabolism Microscopy Optics Phase Preparation Publications Research Research Methodology Research Personnel Resolution Resources Role Sampling Services Spectrum Analysis Structure Techniques Technology Tissues Training Translations United States National Institutes of Health Universities Vision Visualization clinical translation data acquisition imaging approach innovation insight instrument interdisciplinary collaboration member metabolic imaging novel programs spectroscopic imaging synergism temporal measurement wound healing

项目摘要

Project Summary – Imaging and Spectroscopy Core Imaging is a major driver of discovery and translation in biology and medicine. The use of imaging and spectroscopic approaches can often provide insights that may not be available with other techniques that require sample processing. While an Imaging and Spectroscopy Core does not formally exist at the University of Arkansas, the key ingredients necessary to establish one are already present on campus. A range of optical microscopy and spectroscopy instruments are already available for use by other investigators, with several of these set up as service centers. These existing resources will be consolidated and expanded to establish an Imaging and Spectroscopy Core that will meet the research needs of the proposed Arkansas Integrative Metabolic Research Center (AIMRC), have long-term benefits for researchers at the University of Arkansas, and other campuses in the state and in this region of the U.S. The range of technologies available within the Core will allow project leaders to shed new light on cell and tissue metabolism, thus enabling novel discoveries as well as clinical translation of such discoveries. Close interaction between the Imaging and Spectroscopy Core and COBRE project leaders as well as the Data Science and Bioenergetics Cores will lead to new innovations in research methods that will benefit future COBRE investigators as well as the broader campus research community. Hands-on training in imaging technologies will be provided to Center members, the campus and biomedical researchers in Arkansas. The long-term goal of the Imaging Core is to develop and integrate advanced imaging approaches needed by AIMRC members and become fully independent of COBRE support by the end of Phase Ill. The short-term goal for COBRE Phase I is to provide state-of-the-art imaging techniques that can be incorporated into Center projects, develop new image analysis approaches in collaboration with project leaders and the Data Science Core that will support the long-term goal and provide support/educational opportunities to Center members. The specific aims of this proposal are to 1) Establish a state-of-the-art imaging and spectroscopy core at the University Arkansas that meets the needs of the COBRE project leaders and accelerates their progression to independence; 2) Identify and develop new applications of optical microscopy and spectroscopy on campus that synergize with the Bioenergetics and Data Science Cores and lay the foundation for long-term sustainability of the Center; and 3) Provide consultation and coordination, technical assistance and educational opportunities in support of experimental design, sample preparation, data acquisition and analysis, and preparation of high-quality figures for publications and grant applications related to imaging.

项目摘要-成像和光谱学核心