Implementation Science and Health Outcomes Core

实施科学与健康成果核心

• 批准号: 10090641
• 负责人: Denis Nash
• 金额: $ 23.17万
• 依托单位: NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC
• 依托单位国家: 美国
• 财政年份: 1987
• 资助国家: 美国
• 起止时间: 1987-09-30 至 2023-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10090641
• 关键词: AIDS clinical trial group; AIDS prevention; AIDS/HIV problem; Address; Adherence; Affinity; Africa South of the Sahara; Area; Biomedical Technology; Caring; Cities; Clinical Research; Clinical effectiveness; Collaborations; Community Health Systems; Consultations; Continuity of Patient Care; Diagnosis; Discipline; Doctor of Medicine; Doctor of Philosophy; Effectiveness; Epidemic; Epidemiologist; Epidemiology; Evidence based intervention; Fostering; Funding; Gap Junctions; Geographic Locations; HIV; HIV diagnosis; Health; Health Policy; Healthcare Systems; Institutes; Intervention; Link; Mental Health; Mental disorders; Mentors; Modeling; New York; Outcome; Policies; Policy Analysis; Policy Maker; Population Analysis; Prevention; Prophylactic treatment; Psychiatrist; Psychiatry; Public Health; Research; Research Design; Research Infrastructure; Research Personnel; Science; Scientist; Structure; Testing; Time; Translations; United States National Institutes of Health; Universities; Viral; Vulnerable Populations; behavioral study; behavioral/social science; career; clinical center; comorbidity; economic evaluation; effectiveness implementation study; effectiveness research; evidence base; health disparity; implementation intervention; implementation research; implementation science; improved; innovation; interdisciplinary collaboration; interest; low and middle-income countries; novel strategies; population based; population health; practice setting; pre-exposure prophylaxis; prevent; programs; research study; scale up; screening; substance use; uptake; working group

Although millions of lives have been saved by new biomedical technologies and expansion of prevention and treatment in low- and middle-income countries, many vulnerable people – including in the US – are not benefiting from these advances. Implementation science (IS) research can maximize public health impact by addressing suboptimal implementation of evidence-based strategies; identifying ways in which health care systems and policies fail to adequately address the HIV prevention and care continua; and identifying population-based strategies to improve HIV outcomes in the US and globally. The Implementation Science and Health Outcomes (ISHO) Core will address the HIV Center's overall theme by catalyzing innovative IS research that identifies and tests strategies to optimize “real-world” uptake and impact of effective HIV prevention and care continua interventions at scale. The Core has three Specific Aims: (1) to stimulate new IS research and collaborations to improve key outcomes along the HIV prevention and care continua; (2) to advance new IS research to prevent or reduce HIV-related health disparities that are driven by suboptimal intervention implementation or by psychiatric and other comorbidities; and (3) to promote the use of health policy analysis, policy modeling, and economic evaluation to bridge the evidence-practice and evidence-policy gaps that drive suboptimal population-based implementation and disparities. The ISHO Core will accomplish its Aims through functions that include (1) providing expert consultation to HIV Center researchers on conducting IS research that (a) both tests new approaches to improve HIV-related programmatic outcomes and assesses causes of successful and un-successful implementation of interventions and policies at scale, and (b) incorporates the perspectives of policy translation, policy modeling, and economic evaluation into their research; (2) developing Scientific Working Groups to provide structured and focused guidance to (and collaboration with) Center investigators interested in or embarking on IS through dynamic small groups organized around specific themes (e.g., PrEP implementation, psychiatric comorbidities); (3) facilitating access to linked networks for HIV Center investigators addressing IS-related research questions; and (4) sponsoring seminars to stimulate the use of IS approaches in research. The proposed Core Director, Denis Nash, Ph.D., is an epidemiologist and Director of the Institute for Implementation Science in Population Health (ISPH) at the City University of New York. Core Co-Director, Milton Wainberg, M.D., is a research psychiatrist at the New York State Psychiatric Institute and Columbia University Department of Psychiatry. Together they have extensive expertise in NIH-funded research and capacity building for HIV and mental health treatment and prevention. The Core brings together early stage, mid-career, and established investigators in the areas of IS, health-disparities, and economic evaluation with policy-makers and program implementers to provide an infrastructure for research collaboration.

虽然新的生物医学技术和扩大预防措施挽救了数百万人的生命， 在低收入和中等收入国家，许多弱势群体--包括美国--并没有 受益于这些进步。实施科学（IS）研究可以最大限度地提高公共卫生影响， 解决循证战略执行不力的问题;确定卫生保健 制度和政策未能充分解决艾滋病毒预防和护理的连续性问题; 以人口为基础的战略，以改善美国和全球的艾滋病毒结果。实施科学 和健康成果（ISHO）核心将通过促进创新的IS来解决艾滋病毒中心的总体主题 确定和测试策略的研究，以优化“现实世界”的吸收和有效的艾滋病毒的影响 预防和护理继续采取大规模干预措施。核心有三个具体目标：（1）促进新的信息系统 研究和合作，以改善沿着艾滋病毒预防和护理的关键成果;（2） 推进新的信息系统研究，以预防或减少由次优 干预实施或精神病和其他合并症;（3）促进使用健康 政策分析、政策建模和经济评估，以连接证据-实践和证据-政策 差距导致以人口为基础的执行工作不尽人意，而且存在差距。 ISHO核心将通过以下职能实现其目标：（1）提供专家咨询， 艾滋病毒中心的研究人员进行的是研究，（a）既测试新的方法，以改善艾滋病毒相关的 方案成果，并评估成功和不成功执行干预措施的原因 和政策的规模，和（B）纳入政策翻译，政策建模， 经济评估纳入其研究;（2）发展科学工作组，以提供结构化和 通过以下方式向对IS感兴趣或开始IS的中心研究者提供重点指导（并与之合作）： 围绕特定主题组织的充满活力的小组（例如，PrEP实施，精神科 （3）促进艾滋病中心调查人员访问链接网络，解决与IS相关的问题 （4）举办研讨会，鼓励在研究中使用信息系统方法。的 提名的核心主管丹尼斯·纳什博士是一位流行病学家， 纽约城市大学人口健康实施科学。核心联合主任， 医学博士米尔顿温伯格，是纽约州立精神病研究所和哥伦比亚大学的精神病学家 大学精神病学系。他们在NIH资助的研究方面拥有广泛的专业知识， 艾滋病毒和心理健康治疗和预防的能力建设。The Core核心brings带来together一起early早stage阶段， 职业生涯中期，并在IS，健康差异和经济评估领域建立了调查员， 政策制定者和项目实施者为研究合作提供基础设施。