Psychological symptoms in healthcare workers following the COVID-19 pandemic and relationship to long-term cardiovascular risk
COVID-19 大流行后医护人员的心理症状及其与长期心血管风险的关系
基本信息
- 批准号:10558672
- 负责人:
- 金额:$ 78.98万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-02-01 至 2027-01-31
- 项目状态:未结题
- 来源:
- 关键词:Accident and Emergency departmentAcuteAddressAdmission activityAmerican Heart AssociationAnxietyAtherosclerosisBuffersCOVID-19COVID-19 pandemicCOVID-19 patientCOVID-19 treatmentCardiovascular DiseasesCardiovascular systemCaringCessation of lifeDataDatabasesDevelopmentDisease OutbreaksEmergency Department patientEnrollmentEnsureEnvironmentExposure toFrightFutureHealth PersonnelHealth protectionHospitalizationHospitalsHourIndividualInterventionLife ExpectancyLinkLong COVIDMeasuresMental HealthNew YorkNew York CityParticipantPersonal SatisfactionPhysiciansPhysiologicalPoliciesPost-Traumatic Stress DisordersPrevalencePsyche structurePsychological StressPsychological TestsPsychophysiologyPublic HealthRiskSafetyScheduleSleeplessnessSocietiesSpecific qualifier valueStressSubgroupSurveysSymptomsTestingVaccinesWorkacute careacute traumatic stress disordercardiovascular disorder riskcardiovascular healthcardiovascular risk factorcopingcoronavirus diseaseexperiencefollow-uphealingindexinginfection ratemedical specialtiespandemic diseasepandemic impactphysical conditioningprospectiveprotective factorspsychologicpsychological distresspsychological outcomespsychological symptomrecruitresiliencesafety netshift work
项目摘要
Over the past year, the entire world has been upended by the COVID-19 pandemic. As of February 2021, there
have been over 112 million confirmed cases and over 2.5 million deaths globally. In New York City, the initial
US epicenter of the pandemic, there have been >700,000 cases, >89,000 hospitalizations, and >29,000
deaths. Healthcare workers (HCWs) have experienced alarming rates of anxiety, stress, and insomnia due to
COVID-19, which are likely to persist beyond the pandemic. In the proposed work, we will examine the
presence and predictors of long-term psychological symptoms and the consequences for cardiovascular health
among emergency department (ED) HCWs following the COVID-19 pandemic. This work is necessary to
understand the scope of the problem and to inform efforts to protect the health of these frontline HCWs who
have risked their lives to ensure our safety. Pre-COVID, ED HCWs were already known to be at greater
psychological risk than nearly every other subgroup of clinicians. Psycho-physiologic stress factors have been
dramatically magnified during the COVID period, in what has been referred to as a “parallel pandemic” of
surging mental and physical harm faced by HCWs. It is critical to understand the presence of sustained
psychological symptoms seen in HCWs who treated COVID patients, as well as downstream impacts on
cardiovascular health. Our preliminary work showed that HCWs experienced significant acute psychological
distress during the initial COVID peak in New York City. In a survey of hospital HCWs conducted in April
2020, we found high rates of acute stress disorder (65%), anxiety (36%), and insomnia (70%). Early evidence
points to persistence of psychological symptoms. In these participants, 25% experienced post-traumatic stress
disorder (PTSD) and 39% experienced insomnia at a 10 week follow-up. In the proposed study, we will (1)
examine the prevalence and predictors of sustained psychological symptoms in ED HCWs who provided care
during the COVID pandemic; (2) characterize the relationship of psychological symptoms to 3-year progression
of atherosclerotic cardiovascular disease (ASCVD) risk; and (3) examine a potential protective factor (i.e.,
resilient coping) in the development of COVID-related psychological symptoms. To achieve these aims, we will
conduct a prospective 3-year study of psychological and cardiovascular health in ED HCWs exposed to some of
the highest COVID case rates in the world. At study baseline (Year 0) and at each annual follow-up (Years 1-3),
we will conduct a thorough psychological test battery that includes measures of COVID-related PTSD, COVID-
related fear, insomnia, and resilient coping. Each participant’s ASCVD risk score will be computed annually.
Our primary exposure and predictor of psychological symptoms will be the computed “Covid burden,”
quantified as the number of shifts worked between March 1, 2020 (date of our hospital’s index case) and study
enrollment, in which COVID admissions exceeded 15% of total ED patients. Findings will inform interventions
to protect mental and physical wellbeing in HCWs as we navigate this and future public health crises.
在过去的一年里,新冠肺炎大流行颠覆了整个世界。截至2021年2月,有
全球已有超过1.12亿确诊病例和超过250万人死亡。在纽约市,首字母
美国是疫情的中心,已有70万例病例,8.9万人住院,2.9万人
死亡。医护人员(HCW)经历了令人震惊的焦虑、压力和失眠,原因是
新冠肺炎,它们很可能会持续到大流行之后。在建议的工作中,我们会研究
长期心理症状的存在和预测因素及其对心血管健康的影响
在新冠肺炎大流行后的急诊科(ED)卫生工作者中。这项工作是必要的,以
了解问题的范围,并为保护这些前线卫生工作者的健康提供信息
冒着生命危险来确保我们的安全。在冠状病毒感染之前,埃德·霍普金斯大学的医务工作者已经知道
心理风险比几乎所有其他临床医生小组都要高。心理-生理压力因素一直是
在COVID期间被戏剧性地放大,在被称为“平行大流行”的
卫生工作者面临的精神和身体伤害激增。了解持续病毒的存在至关重要
治疗COVID患者的医务人员出现的心理症状以及对
心血管健康。我们的初步工作表明,医务工作者经历了显著的急性心理
在纽约市最初的COVID高峰期的痛苦。在4月份对医院卫生工作者进行的一项调查中
2020年,我们发现急性应激障碍(65%)、焦虑(36%)和失眠(70%)的发病率很高。早期证据
表明心理症状持续存在。在这些参与者中,25%经历了创伤后应激障碍
精神障碍(PTSD)和39%的患者在10周的随访中经历了失眠。在建议的研究中,我们会:(1)
提供护理的急诊科医务人员持续性心理症状的患病率及其预测因素
在COVID大流行期间;(2)描述心理症状与3年进展的关系
动脉粥样硬化性心血管疾病(ASCVD)风险;以及(3)检查潜在的保护因素(即,
弹性应对)在COVID相关心理症状的发展中的作用。为了实现这些目标,我们将
开展一项为期3年的前瞻性研究,调查暴露于某些有害物质的ED医务人员的心理和心血管健康状况
世界上最高的COVID病例比率。在研究基线(第0年)和每次年度随访(第1-3年)时,
我们将进行一系列彻底的心理测试,包括与COVID相关的创伤后应激障碍、COVID-
相关的恐惧、失眠和弹性应对。每位参与者的ASCVD风险评分将每年计算一次。
我们对心理症状的主要暴露和预测将是计算出的“Covid负担”,
量化为2020年3月1日(本院确诊病例之日)至研究期间的工作班次
登记,其中COVID入院人数超过ED患者总数的15%。调查结果将为干预措施提供信息
在我们应对当前和未来的公共卫生危机时,保护卫生工作者的身心健康。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Bernard P. Chang其他文献
The Value of Measuring Diabetes Burnout
- DOI:
10.1007/s11892-021-01392-6 - 发表时间:
2021-06-16 - 期刊:
- 影响因子:6.400
- 作者:
Samereh Abdoli;Danielle Hessler;Mehri Doosti-Irani;Bernard P. Chang;Heather Stuckey - 通讯作者:
Heather Stuckey
Investigating graphesthesia task performance in the biological relatives of schizophrenia patients.
研究精神分裂症患者的生物学亲属的书写感觉任务表现。
- DOI:
- 发表时间:
2004 - 期刊:
- 影响因子:6.6
- 作者:
Bernard P. Chang;M. Lenzenweger - 通讯作者:
M. Lenzenweger
Methodological excursions in pursuit of a somatosensory dysfunction in schizotypy and schizophrenia
寻找精神分裂症和精神分裂症体感功能障碍的方法学探索
- DOI:
- 发表时间:
2003 - 期刊:
- 影响因子:0
- 作者:
M. Lenzenweger;K. Nakayama;Bernard P. Chang;J. Hooley - 通讯作者:
J. Hooley
Frequency of Fentanyl Exposure in Emergency Department Patients With Illicit Drug Use
急诊科非法药物使用患者的芬太尼接触频率
- DOI:
10.1016/j.annemergmed.2024.10.016 - 发表时间:
2025-03-01 - 期刊:
- 影响因子:5.000
- 作者:
Dana L. Sacco;Marc A. Probst;Zachary L. Mannes;Sandra D. Comer;Silvia S. Martins;Bernard P. Chang - 通讯作者:
Bernard P. Chang
Accuracy of the Denver-II in developmental screening.
Denver-II 在发育筛查中的准确性。
- DOI:
- 发表时间:
1992 - 期刊:
- 影响因子:8
- 作者:
F. Glascoe;K. E. Byrne;L. Ashford;K. Johnson;Bernard P. Chang;Bryan Strickland - 通讯作者:
Bryan Strickland
Bernard P. Chang的其他文献
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{{ truncateString('Bernard P. Chang', 18)}}的其他基金
Psychological symptoms in healthcare workers following the COVID-19 pandemic and relationship to long-term cardiovascular risk
COVID-19 大流行后医护人员的心理症状及其与长期心血管风险的关系
- 批准号:
10365638 - 财政年份:2022
- 资助金额:
$ 78.98万 - 项目类别:
Daily personal light exposure patterns and sleep in emergency department healthcare workers (administrative supplement to R01 HL146911)
急诊科医护人员的每日个人光照模式和睡眠(R01 HL146911 的行政补充)
- 批准号:
10666252 - 财政年份:2022
- 资助金额:
$ 78.98万 - 项目类别:
The Identification of Modifiable Emergency Department and Sleep Factors Contributing to Psychological and Cardiovascular Risk in Clinicians
确定导致临床医生心理和心血管风险的可修改急诊室和睡眠因素
- 批准号:
10547767 - 财政年份:2020
- 资助金额:
$ 78.98万 - 项目类别:
The Identification of Modifiable Emergency Department and Sleep Factors Contributing to Psychological and Cardiovascular Risk in Clinicians
确定导致临床医生心理和心血管风险的可修改急诊室和睡眠因素
- 批准号:
9886646 - 财政年份:2020
- 资助金额:
$ 78.98万 - 项目类别:
The Identification of Modifiable Emergency Department and Sleep Factors Contributing to Psychological and Cardiovascular Risk in Clinicians
确定导致临床医生心理和心血管风险的可修改急诊室和睡眠因素
- 批准号:
10319929 - 财政年份:2020
- 资助金额:
$ 78.98万 - 项目类别:
Testing a rapid outpatient management strategy on PTSD, cardiovascular and rehospitalization risk in TIA and minor stroke survivors evaluated in the Emergency Department
测试针对 PTSD、TIA 心血管和再住院风险以及急诊科评估的轻微中风幸存者的快速门诊管理策略
- 批准号:
10448410 - 财政年份:2018
- 资助金额:
$ 78.98万 - 项目类别:
Testing a rapid outpatient management strategy on PTSD, cardiovascular and rehospitalization risk in TIA and minor stroke survivors evaluated in the Emergency Department
测试针对 PTSD、TIA 心血管和再住院风险以及急诊科评估的轻微中风幸存者的快速门诊管理策略
- 批准号:
10208939 - 财政年份:2018
- 资助金额:
$ 78.98万 - 项目类别:
Testing a rapid outpatient management strategy on PTSD, cardiovascular and rehospitalization risk in TIA and minor stroke survivors evaluated in the Emergency Department
测试针对 PTSD、TIA 心血管和再住院风险以及急诊科评估的轻微中风幸存者的快速门诊管理策略
- 批准号:
9754258 - 财政年份:2018
- 资助金额:
$ 78.98万 - 项目类别:
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