Administrative Core

行政核心

• 批准号: 10569659
• 负责人: Jon Scott Thorson
• 金额: $ 84.72万
• 依托单位: UNIVERSITY OF KENTUCKY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-03-01 至 2025-01-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10569659
• 关键词: Address; Agriculture; Arts; Biological; Biology; Biomedical Research; Cancer Center; Cardiovascular Diseases; Career Mobility; Centers of Research Excellence; Chemicals; Clinical; Clinical Sciences; Communication; Decision Making; Development; Development Plans; Devices; Discipline; Disease; Education; Engineering; Ensure; Environment; Evaluation; Faculty; Food; Fostering; Goals; Health; Human Resources; Infrastructure; Institution; Kentucky; Knowledge; Leadership; Medicine; Mentors; Mentorship; Modeling; Molecular Medicine; Obesity; Oral; Outcome; Pharmacologic Substance; Pharmacy facility; Process; Program Effectiveness; Program Evaluation; Research; Research Personnel; Research Priority; Research Support; Resource Allocation; Resource Sharing; Resources; Science; Structure; Systemic disease; Translational Research; Translations; Universities; Validation; career; career development; clinical application; clinical center; college; faculty research; improved; innovation; interdisciplinary collaboration; multidisciplinary; operation; outreach; prevent; primary outcome; programs; stem; success; supportive environment; synergism; tool; tumor metabolism

PROJECT SUMMARY/ABSTRACT – ADMINISTRATIVE CORE We propose to establish a Center of Biomedical Research Excellence (COBRE) in Pharmaceutical Research and Innovation at the University of Kentucky (UK). CPRI will serve as a comprehensive multidisciplinary center focused on translational chemical biology [the nexus of chemical biology (the application of chemical biology principles to develop validated probe/models to advance our understanding of biology) and pharmaceutical science (the application of pharmaceutical principles to advance leads/materials/devices that address unmet clinical needs)]. The COBRE will leverage and develop unique translational chemical biology research support infrastructure/expertise to facilitate junior faculty mentorship and career development, innovative biomedical research probe/tool/model/materials development and validation, and the early advancement of potential ‘translatable’ assets. Within this context, the CPRI Administrative Core will support center communication, coordination, oversight and integration of all COBRE operations, activities, projects, pilots and research support cores. The Core will provide fiscal management and resource oversight, overall coordination of mentoring and career development activities, resource allocation, and program evaluation to ensure program effectiveness. The Administrative Core will also facilitate interactions with related UK programs and centers to foster synergy and coordination of resources. The Core will facilitate the Center’s engagement of junior faculty, researchers, and mentors from UK Colleges (Agriculture, Food & Environment; Arts and Sciences; Engineering; Medicine; Pharmacy and others) to create a vibrant center that seamlessly integrates resources, personnel and knowledge across disciplinary boundaries, and fosters scientific innovation and career development.

项目概要/摘要——行政核心 我们提议在药物研究领域建立生物医学研究卓越中心（COBRE） 肯塔基大学（英国）的创新。 CPRI 将作为一个综合性多学科中心 专注于转化化学生物学[化学生物学的联系（化学生物学的应用 开发经过验证的探针/模型以增进我们对生物学和制药的理解的原则 科学（应用制药原理来推进解决未满足问题的线索/材料/设备 临床需要）]。 COBRE 将利用和开发独特的转化化学生物学研究支持 促进初级教师指导和职业发展的基础设施/专业知识、创新生物医学 研究探针/工具/模型/材料的开发和验证，以及潜力的早期发展 “可翻译”资产。在此背景下，CPRI 行政核心将支持中心沟通、 协调、监督和整合所有 COBRE 运营、活动、项目、试点和研究支持 核心。该核心将提供财务管理和资源监督、指导和协调的总体协调 职业发展活动、资源分配和项目评估，以确保项目的有效性。 行政核心还将促进与英国相关项目和中心的互动，以促进协同作用 和资源协调。核心将促进中心初级教师、研究人员、 以及来自英国大学的导师（农业、食品与环境、艺术与科学、工程、医学、 药房和其他）创建一个充满活力的中心，无缝整合资源、人员和知识 跨越学科界限，促进科学创新和职业发展。