Administrative Core

行政核心

• 批准号: 10569659
• 负责人: Jon Scott Thorson
• 金额: $ 84.72万
• 依托单位: UNIVERSITY OF KENTUCKY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-03-01 至 2025-01-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10569659
• 关键词: Address; Agriculture; Arts; Biological; Biology; Biomedical Research; Cancer Center; Cardiovascular Diseases; Career Mobility; Centers of Research Excellence; Chemicals; Clinical; Clinical Sciences; Communication; Decision Making; Development; Development Plans; Devices; Discipline; Disease; Education; Engineering; Ensure; Environment; Evaluation; Faculty; Food; Fostering; Goals; Health; Human Resources; Infrastructure; Institution; Kentucky; Knowledge; Leadership; Medicine; Mentors; Mentorship; Modeling; Molecular Medicine; Obesity; Oral; Outcome; Pharmacologic Substance; Pharmacy facility; Process; Program Effectiveness; Program Evaluation; Research; Research Personnel; Research Priority; Research Support; Resource Allocation; Resource Sharing; Resources; Science; Structure; Systemic disease; Translational Research; Translations; Universities; Validation; career; career development; clinical application; clinical center; college; faculty research; improved; innovation; interdisciplinary collaboration; multidisciplinary; operation; outreach; prevent; primary outcome; programs; stem; success; supportive environment; synergism; tool; tumor metabolism

PROJECT SUMMARY/ABSTRACT – ADMINISTRATIVE CORE We propose to establish a Center of Biomedical Research Excellence (COBRE) in Pharmaceutical Research and Innovation at the University of Kentucky (UK). CPRI will serve as a comprehensive multidisciplinary center focused on translational chemical biology [the nexus of chemical biology (the application of chemical biology principles to develop validated probe/models to advance our understanding of biology) and pharmaceutical science (the application of pharmaceutical principles to advance leads/materials/devices that address unmet clinical needs)]. The COBRE will leverage and develop unique translational chemical biology research support infrastructure/expertise to facilitate junior faculty mentorship and career development, innovative biomedical research probe/tool/model/materials development and validation, and the early advancement of potential ‘translatable’ assets. Within this context, the CPRI Administrative Core will support center communication, coordination, oversight and integration of all COBRE operations, activities, projects, pilots and research support cores. The Core will provide fiscal management and resource oversight, overall coordination of mentoring and career development activities, resource allocation, and program evaluation to ensure program effectiveness. The Administrative Core will also facilitate interactions with related UK programs and centers to foster synergy and coordination of resources. The Core will facilitate the Center’s engagement of junior faculty, researchers, and mentors from UK Colleges (Agriculture, Food & Environment; Arts and Sciences; Engineering; Medicine; Pharmacy and others) to create a vibrant center that seamlessly integrates resources, personnel and knowledge across disciplinary boundaries, and fosters scientific innovation and career development.

项目摘要/摘要--行政核心 我们建议成立生物医学卓越研究中心(COBRE)进行药物研究 肯塔基大学(英国)的创新与研究。CPRI将作为一个综合性的多学科中心 侧重于翻译化学生物学[化学生物学的纽带(化学生物学的应用 开发有效的探针/模型以促进我们对生物学的理解的原则)和药学 科学(将药学原理应用于解决未满足的问题的先进引线/材料/装置 临床需求)]。科布雷将利用和开发独特的翻译化学生物学研究支持 基础设施/专业知识，以促进初级教师指导和职业发展，创新的生物医学 研究探索/工具/模型/材料的开发和验证，以及潜力的早期进展 “可转换”资产。在这一背景下，CPRI行政核心将支持中心沟通， 协调、监督和整合Cobre的所有业务、活动、项目、试点和研究支持 核心。核心将提供财政管理和资源监督，全面协调指导和 职业发展活动、资源分配和计划评估，以确保计划的有效性。 行政核心还将促进与相关英国方案和中心的互动，以促进协同效应 和资源的协调。该核心将促进中心初级教职员工、研究人员、 和来自英国学院的导师(农业、食品和环境；艺术和科学；工程；医学； 药房和其他)，以创建一个无缝集成资源、人员和知识的充满活力的中心 跨越学科界限，促进科学创新和职业发展。