Challenging Allergies: The Search for a Magic Bullet for Pediatric Food Allergies
挑战过敏:寻找治疗儿童食物过敏的灵丹妙药
基本信息
- 批准号:10578414
- 负责人:
- 金额:$ 4.95万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2023
- 资助国家:美国
- 起止时间:2023-07-12 至 2026-06-30
- 项目状态:未结题
- 来源:
- 关键词:AccidentsAdolescentAdvocateAffectAllergensAllergicAllergy to peanutsAmericanBenefits and RisksBiomedical ResearchBlack raceBooksCessation of lifeChildChildhoodClinicClinical TrialsDataDevelopmentEmpirical ResearchEnrollmentEthnic PopulationEthnographyFamilyFoodFood HypersensitivityFundingGrantGuidelinesHealthHypersensitivityInterviewInvestmentsLifeLiteratureLow incomeMagicManuscriptsMarketingMedicalModelingParentsPathway interactionsPatientsPerceptionPharmaceutical PreparationsPharmacologic SubstancePowder dose formPrivate PracticePrivatizationProtocols documentationPublic HealthQualifyingQuality of lifeReactionReporterResearchResearch PersonnelRiskSafetySalesSamplingSocial SciencesStressStructureTherapeuticTherapeutic InterventionTreatment/Psychosocial EffectsUnderrepresented MinorityUnited StatesUnited States Food and Drug AdministrationUnited States National Institutes of HealthWorkWritingagedclinical practiceeffective therapyexperiencefood allergenfood avoidanceinnovationinterestlensnovel therapeuticsracial populationrecruitresearch and developmentrisk perceptiontreatment comparisonurban area
项目摘要
PROJECT SUMMARY
This project proposes empirical research and a scholarly book on the medicalization and pharmaceuti-
calization of food allergies. One out of every 13 US children has a food allergy, and nearly half of those
children are allergic to multiple foods. Because food allergies can be life-threatening, a significant amount
of biomedical research and development has been invested in finding effective therapies. These novel
therapeutic options—including one recent FDA-approved drug, an array of clinical trials, and even un-
regulated food-based treatments—have attracted considerable parental interest despite potentially sig-
nificant risks. Indeed, preliminary research indicates that parents often have a higher tolerance for the
risks of these medical treatments compared to the risks from food.
I am currently completing an ethnographic study of peanut allergy clinical trials, and the proposed project
will expand and continue this line of research for the scholarly book through three specific aims: (1) ex-
plore the experiences and perceptions of parents of children with peanut or other food allergies who have
not pursued clinical trials, (2) document how unregulated food allergy treatments are being offered
through private practices, and (3) integrate empirical findings from Aims 1 & 2 with my current ethno-
graphic work on food allergy clinical trial participation. For Aim 1, I will conduct 30 interviews with par-
ents who are (a) practicing avoidance of their children's food allergens with no additional treatment, (b)
treating their children's peanut allergy with the FDA-approved drug, or (c) treating their children's food
allergies with unregulated therapies. For Aim 2, I will conduct 10 interviews with clinicians who offer
unregulated food-based treatments for food allergies to analyze how they describe their practices, includ-
ing any safety protocols they have in place. The book manuscript will be written as part of Aim 3, wherein
I will use data from both projects to provide a comprehensive view of food allergy therapeutics.
The proposed project is significant because it will provide rich information about how US families navi-
gate food allergies as a part of everyday life as well as a condition that increasingly justifies risky thera-
peutic interventions. This project is innovative because food allergy therapeutics have not been examined
from a critical social science perspective, and there has been no empirical research comparing the per-
spectives of parents who choose different medical pathways to manage their children's food allergies or
comparing how stakeholders perceive potential differences between FDA-approved, investigational, and
unregulated food allergy treatments. Food allergies are certainly a health threat, but this new era of food
allergy therapeutics marks a transition in which the condition is being more intensely and problematically
medicalized.
项目总结
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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JILL A FISHER其他文献
JILL A FISHER的其他文献
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{{ truncateString('JILL A FISHER', 18)}}的其他基金
Exploring the Ethical Dimensions of Peanut Allergy Immunotherapy Research
探索花生过敏免疫治疗研究的伦理维度
- 批准号:
10308499 - 财政年份:2020
- 资助金额:
$ 4.95万 - 项目类别:
Factors Affecting Healthy Volunteers' Long-Term Participation in Clinical Trials
影响健康志愿者长期参与临床试验的因素
- 批准号:
8536871 - 财政年份:2012
- 资助金额:
$ 4.95万 - 项目类别:
Factors Affecting Healthy Volunteers' Long-Term Participation in Clinical Trials
影响健康志愿者长期参与临床试验的因素
- 批准号:
8611663 - 财政年份:2012
- 资助金额:
$ 4.95万 - 项目类别:
Factors Affecting Healthy Volunteers' Long-Term Participation in Clinical Trials
影响健康志愿者长期参与临床试验的因素
- 批准号:
8664894 - 财政年份:2012
- 资助金额:
$ 4.95万 - 项目类别:
Factors Affecting Healthy Volunteers' Long-Term Participation in Clinical Trials
影响健康志愿者长期参与临床试验的因素
- 批准号:
8852136 - 财政年份:2012
- 资助金额:
$ 4.95万 - 项目类别:
Factors Affecting Healthy Volunteers' Long-Term Participation in Clinical Trials
影响健康志愿者长期参与临床试验的因素
- 批准号:
8370327 - 财政年份:2012
- 资助金额:
$ 4.95万 - 项目类别:
Phase I Clinical Trials and the Informed Consent of Healthy Subjects
I期临床试验和健康受试者的知情同意
- 批准号:
7776864 - 财政年份:2009
- 资助金额:
$ 4.95万 - 项目类别:
Phase I Clinical Trials and the Informed Consent of Healthy Subjects
I期临床试验和健康受试者的知情同意
- 批准号:
7589336 - 财政年份:2009
- 资助金额:
$ 4.95万 - 项目类别:
Informed Consent in Private Sector Mental Health Research
私营部门心理健康研究中的知情同意
- 批准号:
6742231 - 财政年份:2003
- 资助金额:
$ 4.95万 - 项目类别:
Informed Consent in Private Sector Mental Health Research
私营部门心理健康研究中的知情同意
- 批准号:
6803563 - 财政年份:2003
- 资助金额:
$ 4.95万 - 项目类别:
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