Image-Guided Focused Ultrasound Treatment of Abscesses
Image-Guided Focused Ultrasound Treatment of Abscesses
批准号:
10274231
负责人:
Thomas Matula
金额:
$67.55万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2021
资助国家:
美国
项目状态:
未结题
起止时间:
2021-08-01 至 2025-04-30
关键词:
AbscessAcousticsAcuteAcute-Phase ProteinsAffectAftercareAnimalsAntibiotic ResistanceAntibioticsBacteriaBloodBlood CirculationBody partCaringCatheter ManagementCathetersChronicClinical DataClinical TrialsConnective TissueDataDevelopmentDevicesDiseaseDoseDrainage procedureDrug resistanceEvaluationExtravasationFamily suidaeFine needle aspiration biopsyFocused UltrasoundFocused Ultrasound TherapyGaussian modelGoalsHealthcareHematomaHistologicHospital ChargesHospitalizationHumanImageIn VitroInfectionInjuryLength of StayLifeLipopolysaccharidesLiquid substanceMeasuresMechanicsMethodsMicrobeModalityModelingMonitorMorbidity - disease rateNeedlesOperative Surgical ProceduresOryctolagus cuniculusOutcomeOutpatientsPatientsPatternPhysiciansPhysiologic pulsePositioning AttributeProtocols documentationPublic HealthPusRadiationRattusSafetySpecific qualifier valueStreamStructureSurgical complicationTimeTrainingTraumaTreatment EfficacyTreatment ProtocolsUltrasonic TherapyUltrasonographyViscosityarmbasecapsuleclinically relevantcontrast enhancedfirst-in-humanhealinghospital readmissionimage guidedimprovedin vivoinnovationpre-clinicalprocedural painpus collectionresponserisk minimizationstandard of caresuccess
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Abscesses are infected walled-off fluid collections of pus and bacteria and represent a
ubiquitous global healthcare problem. They are common sequelae of surgery, infections,
or disease, and can affect any part of the body. Current standard of care includes
hospitalization, antibiotics, and drainage of the abscess with a catheter. The bacteria in
pus are susceptible mechanical damage with High Intensity Focused Ultrasound (HIFU),
which generates localized cavitation and is a potential noninvasive means to treat
abscesses. The significance of this proposal is that treatment of abscesses using
ultrasound therapy under ultrasound guidance is better for the patient because it is
minimally- or non-invasive, has less procedural pain, doesn’t require that the patient live
for up to several weeks with a drain inserted, requires no catheter management, there is
no potential tract for new infections, and no need for CT/fluoro imaging radiation.
Furthermore, ultrasound treatment will reduce the need for antibiotics, and thus reduce
the potential for drug resistant, life-threatening microbes.
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Focused Ultrasound Treatment of Skin and Soft Tissue Abscesses
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批准号:10646150
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项目类别:
-
资助金额:$69.8万
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财政年份:2022
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负责人:Thomas Matula
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依托单位:
Focused Ultrasound Treatment of Skin and Soft Tissue Abscesses
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批准号:10339133
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项目类别:
-
资助金额:$69.9万
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财政年份:2022
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负责人:Thomas Matula
-
依托单位:
Image-Guided Focused Ultrasound Treatment of Abscesses
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批准号:10447181
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项目类别:
-
资助金额:$67.97万
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财政年份:2021
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负责人:Thomas Matula
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依托单位:
Image-Guided Focused Ultrasound Treatment of Abscesses
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批准号:10620783
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项目类别:
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资助金额:$67.61万
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财政年份:2021
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负责人:Thomas Matula
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依托单位:
HIFU for Noninvasive Abscess Treatment
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批准号:9120875
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项目类别:
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资助金额:$58.43万
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财政年份:2015
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负责人:Thomas Matula
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依托单位:
Physical mechanisms of shock wave therapy in orthopedics
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批准号:7492240
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项目类别:
-
资助金额:$36.25万
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财政年份:2007
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负责人:Thomas Matula
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依托单位:
Physical mechanisms of shock wave therapy in orthopedics
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批准号:7322310
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项目类别:
-
资助金额:$35.42万
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财政年份:2007
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负责人:Thomas Matula
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依托单位:
Physical mechanisms of shock wave therapy in orthopedics
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批准号:7878080
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项目类别:
-
资助金额:$37.5万
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财政年份:2007
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负责人:Thomas Matula
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依托单位:
Physical mechanisms of shock wave therapy in orthopedics
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批准号:7659638
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项目类别:
-
资助金额:$37.0万
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财政年份:2007
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负责人:Thomas Matula
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依托单位:
Ultrasound contrast agent dynamics and vascular effects
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批准号:7650424
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项目类别:
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资助金额:$46.89万
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财政年份:2001
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负责人:Thomas Matula
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依托单位:
Ultrasound contrast agent dynamics and vascular effects
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批准号:7281298
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项目类别:
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资助金额:$47.39万
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财政年份:2001
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负责人:Thomas Matula
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依托单位:
Ultrasound contrast agent dynamics and vascular effects
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批准号:7142345
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项目类别:
-
资助金额:$56.3万
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财政年份:2001
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负责人:Thomas Matula
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依托单位:
海外基金