HIFU for Noninvasive Abscess Treatment
HIFU for Noninvasive Abscess Treatment
批准号:
9120875
负责人:
Thomas Matula
金额:
$58.43万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2015
资助国家:
美国
项目状态:
已结题
起止时间:
2015-08-05 至 2019-07-31
关键词:
AbscessAcousticsAcuteAerobic BacteriaAffectAlamarBlueAnaerobic BacteriaAnimal ModelAntibiotic TherapyAntibioticsAutopsyBacteriaBiological AssayBody partCaringCatheter ManagementCathetersCharacteristicsClinicalCoagulative necrosisControl GroupsDataDevelopmentDevicesDiseaseDrainage procedureDrug resistanceEscherichia coliEvolutionExposure toFocused Ultrasound TherapyGrowthHealthHealth Care CostsHealthcareHeatingHospital ChargesHospitalizationHumanImageIn SituIn VitroInfectionInjuryLeadLength of StayLiquid substanceLocationMeasuresMechanicsModelingMonitorMorbidity - disease rateMuscleOperative Surgical ProceduresOryctolagus cuniculusOutpatientsPainPatientsPhysiciansPilot ProjectsPusRadiationResolutionRiskSamplingSuspension substanceSuspensionsSystemSystemic infectionTemperatureTestingTherapeuticThigh structureTimeTissuesTrainingTraumaTreatment EfficacyUltrasonic TherapyUltrasonographyViscosityWhite Blood Cell Count procedurebactericidecapsulecompare effectivenesscosteffective therapyimage guidedimprovedin vivokillingsprogramspus collectionrectalresearch studyscreeningstandard of caretreatment effect
中文摘要
英文摘要
DESCRIPTION (provided by applicant): Abscesses are infected walled-off fluid collections of pus and bacteria, and represent a ubiquitous global healthcare problem. They are common sequelae of surgery, infections or disease, and can affect any part of the body. Current standard of care includes hospitalization, antibiotics and drainage of the abscess with a catheter. The bacteria in puss are susceptible to both thermal and mechanical damage. High Intensity Focused Ultrasound (HIFU) can generate localized heating and cavitation, and is a potential noninvasive means to treat abscesses by exploiting one or both mechanisms. The significance of this proposal is that noninvasive treatment of reachable abscesses using ultrasound therapy under ultrasound guidance is better for the patient because it is noninvasive, allows treatment of small abscesses, has less procedural pain, requires no catheter management, there is no potential tract for new infections, and no need for CT/fluoro imaging radiation.
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项目类别:
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资助金额:$69.8万
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财政年份:2022
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负责人:Thomas Matula
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依托单位:
Focused Ultrasound Treatment of Skin and Soft Tissue Abscesses
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财政年份:2021
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Physical mechanisms of shock wave therapy in orthopedics
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批准号:7492240
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资助金额:$36.25万
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财政年份:2007
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依托单位:
Physical mechanisms of shock wave therapy in orthopedics
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批准号:7322310
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项目类别:
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资助金额:$35.42万
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财政年份:2007
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依托单位:
Physical mechanisms of shock wave therapy in orthopedics
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批准号:7878080
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项目类别:
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资助金额:$37.5万
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财政年份:2007
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依托单位:
Physical mechanisms of shock wave therapy in orthopedics
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批准号:7659638
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项目类别:
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资助金额:$37.0万
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财政年份:2007
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负责人:Thomas Matula
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依托单位:
Ultrasound contrast agent dynamics and vascular effects
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批准号:7650424
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项目类别:
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资助金额:$46.89万
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财政年份:2001
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负责人:Thomas Matula
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依托单位:
Ultrasound contrast agent dynamics and vascular effects
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批准号:7281298
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项目类别:
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资助金额:$47.39万
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财政年份:2001
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负责人:Thomas Matula
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依托单位:
Ultrasound contrast agent dynamics and vascular effects
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批准号:7142345
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项目类别:
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资助金额:$56.3万
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财政年份:2001
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负责人:Thomas Matula
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依托单位:
海外基金